eIF4GI (D6A6) Rabbit mAb 8701S from Cell Signaling Technology

Product Specs
ItemeIF4GI (D6A6) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8701S
Quantity100 µl
ApplicationsW, IP, IHC-P
ReactivityH, M, R
ClonalityMonoclonal
TargeteIF4G
HostRabbit
NCBI Gene AliasesEIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18
NCBI Full Gene Nameeukaryotic translation initiation factor 4 gamma 1
Research AreaTranslational Control
IsotypeIgG
CloneD6A6
Molecular Weight220

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Signals from the niche promote distinct modes of translation initiation to control stem cell differentiation and renewal in the Drosophila testisPLOS BiologyMarch 11, 2025Ruoxu Wang, Mykola Roiuk, Freya Storer, Aurelio A. Teleman, Marc Amoyelby conventional western blot assay. We used the following antibodies: anti-eIF4G1 (Cell Signaling #8701), anti-eIF4A (Cell Signaling #2490), anti-eIF3b (Santa Cruz, discontinued), phospho-CK2 Substrate (pS/pT)

(2) USP10 promotes cell proliferation, migration, and invasion in NSCLC through deubiquitination and stabilization of EIF4G1Scientific reportsOctober 10, 2024Li F, He Z, Zhang X, Gao D, Xu R, Zhang Z, Cao X, Shan Q, Liu Y, Xu Z.primary antibodies we used were: anti-β-actin (AC026, 1:10000; ABclonal, Wuhan, China); anti-EIF4G1 (8701 S,1:1000), anti-FLAG (2368 S, 1:1000), and anti-IgG (2729 S,1:1000), all from Cell Signaling technology

(3) Interruption of p53-MDM2 Interaction by Nutlin-3a in Human Lymphoma Cell Models Initiates a Cell-Dependent Global Effect on Transcriptome and Proteome LevelCancersJuly 31, 2023Psatha K, Kollipara L, Drakos E, Deligianni E, Brintakis K, Patsouris E, Sickmann A, Rassidakis GZ, Aivaliotis M.included: LC3A/B (12741), MDM2 (86934), p21 (2947), HSP70 (4876), HSP90 (4874), Atg4B (5299S), eiFGI (8701), eiFGE (2067), p4EBP1 (2855), mTOR (2983), pmTOR (2971), S6 (2317), pS6 (4858), AMPKa (2532), p70S6K

(4) Prognostic and functional roles of EIF4G1 in lung squamous cell carcinomaHuman CellMarch 10, 2023Baoxin Bai, Lin Dong, Minghao Feng, Zhiwen Zhang, Ying Lu, Zengguang Xu, Yali Liuthey were subsequently incubated with primary antibodies against EIF4G1 (Cell Signaling Technology #8701, 1:1,000), AKT (Immunoway #YP0007, 1:1,000), p-AKT (ABclonal technology #AP1208, 1:1,000), mTOR (Bioss

(5) Localization of a TORC1-eIF4F translation complex during CD8(+) T cell activation drives divergent cell fateMolecular cellJuly 7, 2022Liedmann S, Liu X, Guy CS, Crawford JC, Rodriguez DA, Kuzuoğlu-Öztürk D, Guo A, Verbist KC, Temirov J, Chen MJ, et al.(04906837001, Roche). Primary antibodies against anti-RagC (5466, Cell Signaling Technology) and anti-eIF4GI (8701, Cell Signaling Technology) were covalently coupled to Dynabeads M-270 Epoxy beads. For detection of

(6) Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complexFrontiers in pharmacologyJanuary 1, 2022Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson SH, Murad R, Beall A, Colayco S, De-Jesus P, Chanda S, et al.Antibodies against eIF4G1, eIF4E and 4EBP1 were purchased from Cell Signaling Technology (respective cat# 8701, cat# 2067, and cat# 9644), and HSP90 antibody was obtained from Santa Cruz Biotechnology (cat# sc-13119).

(7) Elevation of EIF4G1 promotes non-small cell lung cancer progression by activating mTOR signallingJournal of cellular and molecular medicineMarch 1, 2021Lu Y, Yu S, Wang G, Ma Z, Fu X, Cao Y, Li Q, Xu Z.blocking with 3% H2O2, the sections were incubated overnight with primary antibodies (EIF4G1, CST, 8701S, rabbit; mTOR, CST, 5536T, rabbit) at 4°C. Following three washes with phosphate‐buffered saline (PBS)

(8) Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacityProceedings of the National Academy of SciencesOctober 13, 2020Wouter Laurentius Smit et al.https://hgserver1. amc.nl/cgi-bin/r2/main.cgi. EIF4E (Cell Signaling, 9644), EIF4G (Cell Signaling, 8701), pS6 (Cell Signaling, 4857S), and c-MYC (Santa Cruz, sc-764). Immunohistochemistry. Organoids were

(9) Genome-wide analysis of HOXC4 and HOXC6 regulated genes and binding sites in prostate cancer cellsPloS oneJanuary 1, 2020Luo Z, Farnham PJ.14074), THOC4/ ALY (D3R4R; Rabbit mAb, Cell Signaling, 12655), eIF4GI (D6A6; Rabbit mAb, Cell Signaling, 8701) and HOXB13 (D7N8O; Rabbit mAb, Cell Signaling, 90944). The next day, secondary antibodies (Thermo Scientific,

(10) eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancerJCI insightNovember 1, 2019Müller D, Shin S, Goullet de Rugy T, Samain R, Baer R, Strehaiano M, Masvidal-Sanz L, Guillermet-Guibert J, Jean C, Tsukumo Y, et al.(catalog D7F5B), Vimentin (catalog 5741), CyclinD1 (catalog 2978), 4E-BP1 (catalog 9644), eIF4G1 (catalog 8701), p-S6 (catalog 2215), S6K (catalog 2708), p-S6K (catalog 9234), eIF4A (catalog 2013), p473-Akt (catalog

(11) A threonyl-tRNA synthetase-mediated translation initiation machineryNature communicationsMarch 22, 2019Jeong SJ, Park S, Nguyen LT, Hwang J, Lee EY, Giong HK, Lee JS, Yoon I, Lee JH, Kim JH, et al.(sc-74528, 1:1000) from Santa Cruz Biotechnology; GST (#2624, 1:2000), eIF4A (#2013, 1:2000), and eIF4G1 (#8701, 1:2000) from Cell Signaling Technology; α-tubulin (T6074, 1:10,000) and FLAG (F3165, 1:10,000) from

(12) Decreased abundance of eIF4F subunits predisposes low birth weight neonatal pigs to reduced muscle hypertrophyJournal of applied physiology (Bethesda, Md. : 1985)October 1, 2018El-Kadi SW, Chen Y, McCauley SR, Seymour KA, Johnson SE, Rhoads RP.Santa Cruz Biotechnology no. sc-376062; Santa Cruz Biotechnology no. 9742; Cell Signaling Technology no. 8701; Cell Signaling Technology no. 12741; Cell Signaling Technology no. 2195; Cell Signaling Technology no.

(13) EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancerOncogeneJanuary 11, 2018Yamaguchi H, Du Y, Nakai K, Ding M, Chang SS, Hsu JL, Yao J, Wei Y, Nie L, Jiao S, et al.

(14) PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of CancerCancer researchSeptember 1, 2017Hsu JH, Hubbell-Engler B, Adelmant G, Huang J, Joyce CE, Vazquez F, Weir BA, Montgomery P, Tsherniak A, Giacomelli AO, et al.Arginine (R*GG; D5A12; #8711), Mono-Methyl Arginine (Me-R4-100; #8015), eIF4G1 (#2858), eIF4G1 (D6A6; #8701), eIF4E (C46H6; #2067), Phospho-eIF4E (Ser209; #9741), eIF4A (C32B4; #2013), eIF2alpha (D7D3; #5324),

(15) Downregulated Translation Initiation Signaling Predisposes Low-Birth-Weight Neonatal Pigs to Slower Rates of Muscle Protein SynthesisFrontiers in physiologyJanuary 1, 2017Chen Y, McCauley SR, Johnson SE, Rhoads RP, El-Kadi SW.Montgomery, TX eIF3e #AB1114851; Abcam, Cambridge, MA eIF4E #9742; Cell Signaling Technology, Danvers, MA eIF4G #8701; Cell Signaling Technology, Danvers, MA ERK1/2 #4695; Cell Signaling Technology, Danvers, MA IGF-I

(16) Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1Proceedings of the National Academy of SciencesJuly 28, 2015Naotaka Sekiyama, Haribabu Arthanari, Evangelos Papadopoulos, Ricard A. Rodriguez-Mias, Gerhard Wagner, Mélissa Léger-Abrahamanalyzed by Western blotting using a monoclonal antibody against GFP (2956; Cell Signaling) and eIF4GI (8701; Cell Signaling) and a polyclonal antibody against eIF4E (9742; Cell Signaling). Chemiluminescence was

(17) Novel Empty Substrate Integrated Waveguide for High-Performance Microwave Integrated CircuitsIEEE Transactions on Microwave Theory and TechniquesApril 1, 2014Angel Belenguer, Hector Esteban, Vicente E. BoriaGHz 11.0 GHz 19.5 GHz QSIW 314 321 QW R /QSIW 27.71 17.23 QESIW 2219 2750 QESIW /QSIW 7.06 8.57 QW R 8701 5531 QW R /QESIW 3.92 2.01 It can be observed that for 11 GHz the quality factor of the ESIW is theoretically

(18) Lactiplantibacillus plantarum 299v supplementation modulates β-cell ER stress and antioxidative defense pathways and prevents type 1 diabetes in gluten-free BioBreeding ratsGut microbesJanuary 1, 0001Sargin P, Roethle MF, Jia S, Pant T, Ciecko AE, Atkinson SN, Salzman NH, Teng RJ, Chen YG, Cabrera SM, et al.Primary staining utilized the following antibodies: Eif4g (Cell Signaling Technology, Beverly, MA, USA; #8701), Os9 (Abcam, Cambridge, UK; ab109510), Tollip (Proteintech, Chicago, IL, USA; 11315-1-AP), Gsta (Thermofisher Scientific

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eIF4GI (D6A6) Rabbit mAb

eIF4GI (D6A6) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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eIF4GI (D6A6) Rabbit mAb from Cell Signaling Technology

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