Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb 8438S from Cell Signaling Technology

Product Specs
ItemCleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number8438S
Quantity100 µl
ApplicationsW, IF-IC, FC-FP
ReactivityH, M, R
ClonalityMonoclonal
TargetCasp7 (Asp198, 20kD) cleaved
HostRabbit
NCBI Gene AliasesCASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
NCBI Full Gene Namecaspase 7
Research AreaApoptosis
IsotypeIgG
CloneD6H1
Molecular Weight18

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) VLX1570 suppresses neuroblastoma growth through inhibition of PCNA-associated proliferative signaling and potentiates cisplatin antitumor activityFront PharmacolJuly 15, 2026Wei-Hsun Yang, Chong-Sun Khoi, Kuan-Lin Kuo, Po-Ming Chow, Chen-Hsun Hsu, Yi-Ju Kao, Wei-Chou Lin, Shang-Jen Chang, Shih-Ming Liao, Felicia Tai, et al.(#12827), poly(ADP-ribose) polymerase (PARP; #9542), cleaved caspase-3 (#9664), cleaved caspase-7 (#8438), cleaved PARP (#9541), Bcl-2 (#15071), PCNA (#13110), phospho-histone H3 (#53348), and phospho-histone

(2) Biotinylated Diaryl Isoxazole Derivatives with Enhanced Janus Kinase 1 Inhibitory, Antiproliferative, and Apoptotic Activities in Cancer CellsACS OmegaJune 30, 2026Melike Ergüven, Hazal Beril Çatalak Yılmaz, Deniz Lengerli, Rana Acar, Servin Bagheralmoosavi, Yağmur Öykü Carus Şahin, Mehmet Gürçay, Burcu Çalışkan, Sreeparna Banerjee, Gurkan Yesiloz, et al.(Cell Signaling Technologies, Cat. No. 9661), cleaved Caspase-7 (Cell Signaling Technologies, Cat. No. 8438), and cleaved PARP (Cell Signaling Technologies, Cat. No. 5625) were utilized. Secondary antibodies

(3) U2AF2-regulated alternative splicing of UPP1 promotes NSCLC progression by enhancing glycolysisCell Communication and SignalingMay 18, 2026Hongyu Pan, Xinyue Liang, Yahan Qin, Yujian Xu, Ke Xue, Lei Sun, Wenjun Chai, Xiaoli Liu, Yue Cao, Jing Li, et al.µL), Caspase-3 (rabbit, CST, 9664), cleaved Caspase-3 (rabbit, CST, 9542), Caspase-7 (rabbit, CST, 8438), cleaved Caspase-7 (rabbit, CST, 84384), and HRP-conjugated β-actin (Proteintech, HRP-66009). After

(4) Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infectionNature immunologyMay 1, 2026Liu W, Ping J, Deng L, Wang K, Xu J, Peng N, Yang M, Tang H, Liu Z, Wang W, et al.Anti-MPO (AF3667) was obtained from R&D systems. Antibodies against caspase-3 (9662), caspase-7 (D6H1, 8438), caspase-8 (D5B2, 8592), caspase-9 (9504), phospho-ERKT202/Y204 (4370) and phospho-PKC (βII Ser660,

(5) Differential regulation of retinoic acid metabolism in Fanconi anemiaScientific ReportsApril 30, 2026Justin L. Blaize, Bahaa M. Noori, Kelsey P. Hunter, Kathryn A. Henrikson, Janet A. Atoyan, Alan A. Ardito, Abygail G. Chapdelaine, Gongqin Sun, Frank X. Donovan, Settara C. Chandrasekharappa, et al.(2197; Cell Signaling), Cleaved Caspase-3 (D175) (9664; Cell Signaling), Cleaved Caspase-7 (D198) (8438; Cell Signaling), Cleaved PARP (D214) (5625; Cell Signaling), and H2AX pS139 (γH2AX) (9718; Cell Signaling),

(6) Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophagesPLOS PathogensApril 27, 2026Madhura Kulkarni, Christopher M. Bourne, Ashutosh B. Mahale, Patrick M. Exconde, Cecelia Murphy, Haley T. Goodrow, Sofia Cervantes, Matilda Kardhashi, Mirai Kambayashi, William Yoo, et al.2276S), CASP3 (Cell Signaling Tech 9664S), CASP3 (Cell Signaling Tech, 9662), CASP7 (Cell Signaling Tech, 8438S), CASP7 (Cell Signaling Tech, 12827S), GSDME (Abcam, ab215191), hIL-1β Goat Polyclonal Ab (R&D systems,

(7) Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 DegradersbioRxivApril 17, 2026Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Min Zhang, Bin Yang, Jingjing Chen, Feng Li, Xiaoli Qi, Jin Wang(3493, Cell Signaling Technology (CST)), anti-cleaved caspase 3 (9661, CST), anti-cleaved caspase7 (8438, CST), anti-cleaved PARP (5625,CST), and anti-β-actin (4970, CST). The membranes were then incubated

(8) Lipid droplet-induced T cell death sustains autoimmune tissue inflammationCell MetabolismApril 7, 2026Jitendra Kumar, Yoshinori Takashima, Jose Morales, Brandon Wong, Lina Werner, Isabel N. Goronzy, Selene Rubino, Robert T. Trousdale, Gerald J. Berry, Jörg J. Goronzy, et al.,Cell Signaling Technology,#9664; P42574 Caspase-7 Cleaved (Asp198) (D6H1) Rabbit mAb,Cell Signaling Technology,#8438; P55210 Caspase-8 Cleaved (Asp374) (18C8) Rabbit mAb,Cell Signaling Technology,#9496; Q14790 CD44

(9) Edelfosine induces cell cycle arrest and apoptosis in vascular smooth muscle cells to suppress neointimal hyperplasiaScientific ReportsMarch 25, 2026Jiaxing Sun, Yu Gui, Yuxin Liu, Yanan Guo, Rosana González Granado, Liam Guetg, Warren Peng, Shenghua Zhou, Xi-Long Zhengcaspase-3 (#14220), cleaved caspase-3 (#9664), GAPDH (#5174), caspase-7 (#12827), cleaved caspase-7 (#8438), caspase-9 (#9508), cleaved caspase-9 (#52873), Bax (#2772), eIF2α (#9722), phospho-eIF2α (#9721),

(10) HIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancerCell Reports MedicineMarch 17, 2026Yong Wang, Yan Xiong, Shuiqiao Liu, Lei Bao, Xing Qiu, Ilia Korboukh, Xiangyang Song, Vanina Toffessi Tcheuyap, Sipeng Wu, Mingyi Chen, et al.anti-cleaved-caspase-3 antibody (9661S, Cell Signaling Technology), anti-cleaved-caspase-7 antibody (8438S, Cell Signaling Technology), anti-PARP1 antibody (9542S, Cell Signaling Technology), anti-caspase-10

(11) The metabolite α-ketoglutarate induces AIM2-dependent PANoptosis through demethylase TET2Cell Communication and SignalingFebruary 16, 2026Yi Li, Qing Tu, Chenchen Liu, Jiamin Ma, Yuwei Chen, Lin Wang, Ying Chen, Jinbao Li, Jiali Zhu, Yun Zou, et al.Caspase7 (1:2000,Cell Signaling Technology, #9497), Cleaved-Caspase7 (1:1000,Cell Signaling Technology, #8438), receptor-interacting protein kinase 1 (RIPK-1) (1:2000,Cell Signaling Technology, #3493), phosphorylated

(12) Targeted suppression of DNA polymerase θ enhances calcium flux and triggers intrinsic apoptosis in gastric cancerCancer Cell InternationalFebruary 5, 2026Yan Wang, Junjun Nan, Yangchan Hu, Yuxin Meng, Bing Wang, Zu Ye, Xiaohe Chu, Ji Jing, Xiangdong Chengcaspase-3 (1:500, Cat. No. 9661 S, Cell Signaling Technology, USA), cleaved caspase-7 (1:500, Cat. No. 8438 S, Cell Signaling Technology, USA),γ-H2AX (1:1000, Cat. No. AB81299, Abcam, UK), RPA32 (1:10,000, Cat.

(13) Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancerInt J Mol MedFebruary 2, 2026Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, et al.caspase-3 (Cell Signaling Technology, Inc.; cat. no. 9664), -7 (Cell Signaling Technology, Inc.; cat. no. 8438) and -8 (Cell Signaling Technology, Inc.; cat. no. 9496), Bax (Cell Signaling Technology, Inc.; cat.

(14) Synaptotagmin-7 drives stress-induced cardiomyocyte necroptosis via the p53-Bak-mPTP axisTheranosticsJanuary 1, 2026Jialei Li, Shuang Wang, Yu Han, Jinhong Liu, Yuhan Li, Jingyu Zhang, Liping Guo, Yue Jin, Jiasong Chang, Ting Liu, et al.3 (CST, USA, #9664), anti-Cleaved Caspase 9 (CST, USA, #52873), anti-Cleaved Caspase 7 (CST, USA, #8438), anti-Bax (CST, USA, #2772), anti-Bim (CST, USA, #2933), anti-Bik (CST, USA, #4592), anti-PHOSPHO-MLKL (SER358

(15) The Microbial Bile Acid Metabolite 3-oxo-LCA Inhibits Colorectal Cancer ProgressionCancer ResDecember 15, 2025Fei Sun, Ke Wang, Xingchen Dong, Henry Secaira-Morocho, Alisa Hui, Chunmiao Cai, Jonathan J. Sze, Brian Low, Shirsa Udgata, Cheri A. Pasch, et al.1:200, cat #8480s, RRID:AB_11127855; anti-Olfm4, 1:200, cat#14472s; anti-Cleaved Caspase 7, 1:200, cat#8438, RRID:AB_11178377; anti-Cleaved Caspase 3, 1:200, cat#9664, RRID:AB_2070042) in IF buffer with 1% BSA

(16) The Microbial Bile Acid Metabolite 3-Oxo-LCA Inhibits Colorectal Cancer ProgressionCancer ResearchDecember 15, 2025Fei Sun, Ke Wang, Xingchen Dong, Henry Secaira-Morocho, Alisa Hui, Chunmiao Cai, Jonathan J. Sze, Brian Low, Shirsa Udgata, Cheri A. Pasch, et al.1:200, cat #8480s, RRID:AB_11127855; anti-Olfm4, 1:200, cat#14472s; anti-Cleaved Caspase 7, 1:200, cat#8438, RRID:AB_11178377; anti-Cleaved Caspase 3, 1:200, cat#9664, RRID:AB_2070042) in IF buffer with 1% BSA

(17) Design, Optimization, and Development of RIPK1 Degraders with Improved Pharmacokinetic and Pharmacodynamic PropertiesJournal of Medicinal ChemistryNovember 13, 2025Dong Lu, Xin Yu, Hanfeng Lin, Ran Cheng, Bin Yang, Min Zhang, Jingjing Chen, Feng Li, Xiaoli Qi, Jin Wang(3493, Cell Signaling Technology (CST)), anti-cleaved caspase 3 (9661, CST), anti-cleaved caspase7 (8438, CST), anti-cleaved PARP (5625,CST), and anti-β-actin (4970, CST). The membranes were then incubated

(18) The SRC-TOPK positive feedback loop promotes RB1 phosphorylation and drives the development of lung squamous cell carcinoma: SRC and TOPK promote LUSC cell growth by regulating RB1Acta Biochimica et Biophysica SinicaSeptember 5, 2025Xiaofei Zeng, Longzhen Cui, Beibei Tang, Fei Wang, Hua He, Feng Zhu, Minjie Ma, Chang Chen1:1000), P-ERK (#9101, 1:1000), RB (#9309, 1:1000), Cleaved-PARP (#5625, 1:500) and Cleaved Caspase-7 (#8438, 1:1000) were purchased from Cell Signaling Technology (Boston, USA). anti-HA tag (51064-2-AP, 1:2500),

(19) Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitorsElifeJuly 23, 2025Dongyue Jiao, Kun Chang, Jiamin Jin, Yingji Chen, Mo Ren, Yucong Zhang, Kun Gao, Yaoting Xu, Lixin Wang, Chenji Wangpolyclonal),CST,Cat# 9492 S RRID:AB_2228313,WB(1:1000) Antibody,anti-cleaved CASP7 (Rabbit monoclonal),CST,Cat# 8438 S RRID:AB_11178377,IF(1:200) Antibody,anti-CASP3 (Rabbit monoclonal),CST,Cat# 9668 S RRID:AB_2069870,WB(1:1000) Antibody,anti-cleaved

(20) Targeting the WSB2-NOXA Axis in Cancer Cells for Enhanced Sensitivity to BCL-2 Family Protein InhibitorsElifeJuly 23, 2025Dongyue Jiao, Kun Chang, Jiamin Jin, Yingji Chen, Ren Ren, Yucong Zhang, Kun Gao, Yaoting Xu, Lixin Wang, Chenji Wangpolyclonal),CST,Cat# 9492 S RRID:AB_2228313,WB(1:1000) Antibody,anti-cleaved CASP7 (Rabbit monoclonal),CST,Cat# 8438 S RRID:AB_11178377,IF(1:200) Antibody,anti-CASP3 (Rabbit monoclonal),CST,Cat# 9668 S RRID:AB_2069870,WB(1:1000) Antibody,anti-cleaved

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Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb

Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (202)

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Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb from Cell Signaling Technology

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