MMP-7 Antibody AF2967 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMMP-7 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF2967
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization
TargetMMP-7
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Quantity100 ug (also 25 ug)
IsotypeIgG
ReactivityHuman,Mouse,Transgenic Mouse
HostGoat
Conjugate/TagUnconjugated
ClonalityPolyclonal
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namematrix metallopeptidase 7
NCBI Gene AliasesMMP-7, MPSL1, PUMP-1
PurityAntigen Affinity-purified
ConcentrationLYOPH
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse MMP-7, Leu18-Leu264, Accession # AAA99983

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse MMP-7 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human MMP-7 is observed, and less than 2% cross-reactivity with recombinant mouse (rm) MMP-2, rmMMP-3, rmMMP-8, and rmMMP-9 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal EpitheliumCellular and molecular gastroenterology and hepatologyJanuary 1, 2021Murray E, Cheng X, Krishna A, Jin X, Ohara TE, Stappenbeck TS, Bose R.

(2) FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancereLifeNovember 26, 2018Camolotto SA, Pattabiraman S, Mosbruger TL, Jones A, Belova VK, Orstad G, Streiff M, Salmond L, Stubben C, Kaestner KH, et al.#: ab31159, RRID:AB_ 881276 IHC (1:800) Antibody Polyclonal goat anti-MMP7 R and D Systems Cat. #: AF2967, RRID: AB_664120 IHC (1:400) Antibody Mouse monoclonal anti-Muc5AC Abnova Cat. #: MAB13117 IHC

(3) Parasitic helminths induce fetal-like reversion in the intestinal stem cell nicheNatureJuly 1, 2018Nusse YM, Savage AK, Marangoni P, Rosendahl-Huber AKM, Landman TA, de Sauvage FJ, Locksley RM, Klein OD.Signaling Technology), Sca-1 (e13-161.7, Biolegend), Muc2 (SC-15334, Santa Cruz Biotechnology), Mmp7 (AF2967, R&D Systems). EdU was detected using Click-iT Plus EdU Assay Kit (ThermoFisher). Organoid culture Cultures

(4) Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem CellsCell reportsMarch 14, 2017Nalapareddy K, Nattamai KJ, Kumar RS, Karns R, Wikenheiser-Brokamp KA, Sampson LL, Mahe MM, Sundaram N, Yacyshyn MB, Yacyshyn B, et al.

(5) Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transitionOncogeneFebruary 2, 2017Zhang Q, Liu S, Parajuli KR, Zhang W, Zhang K, Mo Z, Liu J, Chen Z, Yang S, Wang AR, et al.Abcam, Cambridge, MA); rabbit anti-laminin (#L9393, Sigma-Aldrich, St. Louis, MO); goat antiMMP7 (#AF2967, R&D Systems, Minneapolis, MN). For immunofluorescence staining, monolayer cultured cells were fixed

(6) Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasisJCI insightJuly 7, 2016Belinson H, Savage AK, Fadrosh D, Kuo YM, Lin D, Valladares R, Nusse Y, Wynshaw-Boris A, Lynch SV, Locksley RM, et al.Scientific), rat anti–E-cadherin (13-1900 Invitrogen), rabbit anti-lysozyme (A0099 Dako), and goat anti-MMP7 (AF2967 R&D Systems). After immunohistochemistry, slides were mounted with DAPI counterstain (Invitrogen, P36930). Primary

(7) 253 TSC2/mTORC1 Signaling Controls Paneth and Goblet Cell Differentiation in the Intestinal EpitheliumGastroenterologyApril 1, 2015Yuning Zhou, Piotr Rychahou, Qingding Wang, Heidi L. Weiss, B. Mark Eversrabbit chromogranin A (Abcam, Cambridge, MA, USA; 15160), mouse MMP7 (R&D Systems, Minneapolis, MN, USA; AF2967) and rabbit Ki67 (Novus, Littleton, CO, USA; NB110-89717). Negative controls (including no primary antibody

(8) Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosisPloS oneJanuary 1, 2013Nkyimbeng T, Ruppert C, Shiomi T, Dahal B, Lang G, Seeger W, Okada Y, D'Armiento J, Günther A.with mouse anti-human MMP-13 (5µg/ml, #MAB13424, Chemicon) [human] or goat anti-mouse MMP-7 (15µg/ml, #AF2967, R&D Systems) [murine]. After three washes with PBS, a biotinylated secondary anti-Ig was applied followed

(9) Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse modelsCancer researchMay 15, 2012Zhang Q, Liu S, Ge D, Zhang Q, Xue Y, Xiong Z, Abdel-Mageed AB, Myers L, Hill SM, Rowan BG, et al.

(10) Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progressionCancer researchMarch 15, 2010Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI, Werb Z.

(11) Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptorCancer researchJuly 15, 2007Lynch CC, Vargo-Gogola T, Martin MD, Fingleton B, Crawford HC, Matrisian LM.

(12) TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epitheliumCell death & diseaseJanuary 1, 0001"Zhou Y, Rychahou P, Wang Q, Weiss HL, Evers BM."rabbit chromogranin A (Abcam, Cambridge, MA, USA; 15160), mouse MMP7 (R&D Systems, Minneapolis, MN, USA; AF2967) and rabbit Ki67 (Novus, Littleton, CO, USA; NB110-89717). Negative controls (including no primary antibody

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MMP-7 Antibody

MMP-7 Antibody

MMP-7 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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MMP-7 Antibody from R&D Systems, a Bio-Techne Brand

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