Pitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop®2 ab120688 from Abcam

Product Specs
ItemPitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop®2
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120688
Quantity5 mg
TypeInhibitor
Molecule NamePitstop® 2 - negative control

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Investigating the mechanisms of indocyanine green tumour uptake in sarcoma cell lines and ex vivo human tissueThe Journal of PathologySeptember 10, 2025Corey David Chan, Marcus J Brookes, Toni A Pringle, Rahul Pal, Riya Tanwani, Alastair D Burt, James C Knight, Anand TN Kumar, Kenneth S Rankinwere incubated with 5–30 μm of Pitstop 2 (Abcam; ab120687) or 30 μm Pitstop 2 negative control (Abcam; ab120688) diluted in serum‐free media containing 0.1% DMSO for 15 min at 37 °C. After 15 min, ICG in serum‐free

(2) Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNAScienceAugust 14, 2025Lauren Murphy, Jeanne Inchauspé, Giampiero Valenzano, Pamela Holland, Nikolaos Sousos, Hayley L. Belnoue-Davis, Rong Li, Natalie J. Jooss, Camelia Benlabiod, Eleanor Murphy, et al.ab120464-5mg, 30 µM), Pitstop (Abcam, cat # ab120687, 25 µM), Pitstop 2 Negative control, (Abcam, cat # ab120688, 25 µM), Cytochalasin D (Santa Cruz Biotechnology, cat # CAS 22144-77-0, 5 µM), Nystatin (Merck Life

(3) The CLIC/GEEC pathway regulates particle uptake and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophagesPLoS PathogMarch 11, 2025Kathleen Candor, Lingmei Ding, Sai Balchand, Jason E. Hammonds, Paul Spearman20 μM. Pitstop 2.0 (Cat SML1169) was obtained from Sigma-Aldrich and Pitstop negative control (Cat AB120688) was obtained from Abcam and used at a concentration of 5 μM. 7-Keto Cholesterol (7-KC) (Cat 16339)

(4) Mitsugumin 53 Inhibits Angiogenesis Through Regulating Focal Adhesion Turnover and Tip Cell FormationJ Cell Mol MedFebruary 24, 2025Shuangshuang Yuan, Qin Yu, Tangting Chen, Tian Li, Yongjie Li, Xin Deng, Ni Chen, Jingcan You, Rong Li, Yan Liu, et al.antibody were obtained from Merck (Darmstadt, Germany). Pitstop‐2 (ab120687), pitstop‐2 negative control (ab120688), anti‐MG53 antibody (#ab83302) used for western blotting and anti‐active integrin β1 antibody (#ab30394)

(5) Membrane Tension Regulation is Required for Wound RepairAdvanced ScienceDecember 1, 2024Nikita Raj, Martin S. Weiß, Bart E. Vos, Sarah Weischer, Frauke Brinkmann, Timo Betz, Britta Trappmann, Volker Gerkethe imaging assay. Pitstop‐2 negative control was used correspondingly in the same experiment (Abcam, ab120688) as a compound control. Fluorescently labeled transferrin uptake (Transferrin‐Alexa Fluor 488, Thermo Fisher Scientific

(6) Mapping of Tilapia Lake Virus entry pathways with inhibitors reveals dependence on dynamin activity and cholesterol but not endosomal acidificationFrontiers in Cell and Developmental BiologyDecember 16, 2022Reem Abu Rass, Japhette Esther Kembou-Ringert, Rachel Zamostiano, Avi Eldar, Marcelo Ehrlich, Eran Bacharach(10 µm; Abcam, ab141930). Pitstop 2 (30 µm; Abcam, ab120687) and its negative control (30 µm; Abcam, ab120688), which has a highly related structure to pitstop 2 and fails to inhibit endocytosis even at high concentrations

(7) Sterolight as imaging tool to study sterol uptake, trafficking and efflux in living cellsScientific reportsApril 15, 2022Králová J, Popr M, Valečka J, Bartůněk P.(C2618) and latrunculin A (428021) were from Merck. Pitstop 2 (ab120687) and negative control–pitstop 2 (ab120688) were from Abcam, and verapamil was from SiR-tubulin kit (SC002) provided by Spirochrome. Antibodies Anti-clathrin heavy chain

(8) SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosisThe Journal of biological chemistryJanuary 1, 2021Bayati A, Kumar R, Francis V, McPherson PS.20 min, respectively. DMSO was used as a control for Dynasore and Pitstop 2 negative control (Abcam, ab120688). After incubation, drug-containing media was replaced with spike protein (3 μg per 200 μl of media)

(9) CLIC4/Arf6 PathwayCirculation researchJanuary 4, 2019Abdul-Salam VB, Russomanno G, Chien-Nien C, Mahomed AS, Yates LA, Wilkins MR, Zhao L, Gierula M, Dubois O, Schaeper U, et al.endocytosis inhibitor Pitsop2 (20 μmol/L; ab120687; Abcam)16 or Pitstop2-negative control (20 μmol/L; ab120688; Abcam,) for 2 hours. Pitsop2-negative control is chemically related to Pitstop2 but does not block

(10) Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T LymphocytesJournal of immunology (Baltimore, Md. : 1950)September 15, 2016Chang HF, Bzeih H, Schirra C, Chitirala P, Halimani M, Cordat E, Krause E, Rettig J, Pattu V.3C and 3D, cells were pretreated with 15 mM pitstop2 (ab120687; Abcam) or pitstop2 negative control (ab120688; Abcam) for 3 min at room temperature in serum-free IMDM. For Fig. 3G and 3H, CTLs were transfected

(11) HSV ‐1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin‐Dependent EndocytosisTrafficJanuary 1, 2016Anna Albecka, Romain F. Laine, Anne F.J. Janssen, Clemens F. Kaminski, Colin M. CrumpDynole‐31‐2 (Dynole Negative) were used at 15 µm, while PitStop 2™ (ab120687) and PitStop2 negative control (ab120688) at 30 µm. Dilutions were prepared in serum‐free medium. All inhibitors were purchased from Abcam. Dominant‐negative

(12) Clathrin inhibitor Pitstop-2 disrupts the nuclear pore complex permeability barrierScientific ReportsSeptember 1, 2015Ivan Liashkovich, Dzmitry Pasrednik, Valeria Prystopiuk, Gonzalo Rosso, Hans Oberleithner, Victor Shahinwith a Pitstop-2 negative control compound which is structurally highly similar to Pitstop-2 (Abcam, ab120688) was unable to induce the influx of 65–85 kDa dextran similarly to the effect of 0.1% DMSO alone used

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Pitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop®2 from Abcam

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Pitstop® 2 - negative control, Negative control for clathrin inhibitor Pitstop®2 from Abcam

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