Dynasore, dynamin inhibitor ab120192 from Abcam

Product Specs
ItemDynasore, dynamin inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120192
Quantity10 mg, 50 mg
Purity0.99
TypeInhibitor, inhibitor
Molecule NameDynasore

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Website: http://www.abcam.com

(1) Spectrin condensates provide a nidus for assembling the axonal membrane-associated periodic skeletoniScienceJanuary 16, 2026Nicholas P. Boyer, Rohan Sharma, Theresa Wiesner, Christopher Parperis, Antoine Delamare, Florence Pelletier, Nicolas Jullien, Anshul M. Bhatt, Leonardo A. Parra-Rivas, Patrick J. Kearney, et al.and recombinant proteins","Chemicals, peptides, and recombinant proteins" ,, Dynasore,Abcam,Cat# ab120192 Alexa Fluor 488 conjugated phalloidin,Invitrogen,Cat# A12379 Alexa Fluor Plus 647–phalloidin,Invitrogen,Cat#

(2) Molecular and biophysical requirements for B cell receptor dependent enhancement of dengue virus infectionbioRxivJanuary 7, 2026Gaby Madrigal, Chad Gebo, Benjamin D. McElvany, Sean A. Diehl, Adam T. Waickmanpharmacological inhibitors: 12.5μM, 50μM, and 200μM of dynamin inhibitor Dynasore (Abcam, cat. no. ab120192); 1.56μM, 12.5μM, and 50μM of BTK inhibitor Ibrutinib (Selleck, cat. no. S2680); or 1.56μM, 12.5μM,

(3) P-glycoprotein exofection between fetal and maternal cells as a mechanism of intercellular material transfer at the feto maternal interfacebioRxivJanuary 6, 2026Madhuri Tatiparthy, Amanda Wang, Vineeth Mahajan, Pilar Flores-Espinosa, Emmanuel Amabebe, Tilu Jain Thomas, Xiao-Ming Wang, Lauren S Richardson, Ramkumar Menon, Ananth K Kammalaand their propagation was assessed. For the inhibitor studies, drugs such as Dynasore (Abcam, Cat# ab120192), Wortmannin (Abcam, Cat# ab120148), Amiloride (Abcam, Cat# ab120281), Chlorpromazine (Sigma, Cat# 31679),

(4) A physiological microfluidic blood-brain-barrier model for in vitro study of nanoparticle trafficking and accumulationbioRxivSeptember 11, 2025Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan-Wei Huang, Hannah O’Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carneyincubation using confocal microscopy. Poisoning BBB uptake mechanisms Dynasore (ABCAM Inc, Cat. # ab120192) and Imipramine (Sigma Aldrich, Cat. # I7379–5G) were used to inhibit dynamin associated transcytosis

(5) Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communicationCell metabolismAugust 5, 2025Tong JCL, Frazer-Morris C, Shilleh AH, Viloria K, de Bray A, Nair AM, Johnson PRV, Spiers R, Kobiita A, Olaniru OE, et al.6927 Glucagon,Sigma-Aldrich,G2044 GIP,Bachem,4030658 Exendin 9-39,Sigma-Aldrich,E7269 Dynasore,Abcam,ab120192 Dyngo4a,Abcam,ab120689 BG-Sulfo646,Johannes Broichhagen (Leibniz-FMP),10.1038/s41467-022-35716-1 and

(6) Neurodegenerative disease-associated microRNAs acting as signaling molecules modulate CNS neuron structure and viabilityCell communication and signaling : CCSApril 24, 2025Kumbol V, Ivanov A, McGurran H, Schüler J, Zhai Y, Ludwik K, Hinkelmann L, Brehm M, Krüger C, Küchler J, et al.plates at 2 × 105 cells/well. After 3 d in vitro, cells were treated with Dynasore (200 µM, Abcam #ab120192, Cambridge, UK) or DMSO for 1 h. Next, cells were incubated with a mixture of pHrodo Red Dextran (20

(7) Unite and Conquer: Association of Two G-Quadruplex Aptamers Provides Antiproliferative and Antimigration Activity for Cells from High-Grade Glioma PatientsPharmaceuticals (Basel, Switzerland)October 26, 2024Pavlova S, Fab L, Dzarieva F, Ryabova A, Revishchin A, Panteleev D, Antipova O, Usachev D, Kopylov A, Pavlova G.described above. Standard culture medium was replaced with serum-free medium with 100 µM Dynasore (ab120192, Abcam, Cambrige, UK) and cells were incubated for 30 min, followed by the addition of FAM-bi-(AID-1-T)

(8) Physiological roles of endocytosis and presynaptic scaffold in vesicle replenishment at fast and slow central synapseseLifeJune 3, 2024Satyajit Mahapatra, Tomoyuki Takahashiresource,Designation,Source or reference,Identifiers,Additional information "Chemical compound, drug",Dynasore,Abcam,Cat# ab120192,100 µM "Chemical compound, drug",Pitstop-2,Abcam,Cat# ab120687,25 µM "Chemical compound, drug",ML141,Abcam,Cat#

(9) Mechanisms of aquaporin‐4 vesicular trafficking in mammalian cellsJournal of NeurochemistryFebruary 1, 2024Andrea Markou, Philip Kitchen, Ahmed Aldabbagh, Mariaelena Repici, Mootaz M. Salman, Roslyn M. Bill, Zita Balklavacompounds, the following concentrations and pre‐incubation times were used: dynasore (Abcam, Cat. nr. ab120192) 10 μM, 30 min (Bandmann et al., 2019); filipin (Sigma Aldrich, Cat. nr. F9765) 15 μM, 45 min (Orlandi

(10) A quantitative in vitro collagen uptake assayMethodsXDecember 1, 2023Sjors Maassen, Harry M. Warner, Pieter Grijpstra, Geert van den Bogaart(full name: 3-hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide; Abcam, Cat no. AB120192) at 0, 10 and 100 µM (from a 50 mM stock solution in anhydrous DMSO) while being cultured on collagen

(11) Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cellsJournal of virologyOctober 31, 2023Becker M, Conca DV, Dorma N, Mistry N, Hahlin E, Frängsmyr L, Bally M, Arnberg N, Gerold G.fixation (DPH + 2% FBS). Small molecule inhibitors were pitstop2 (Abcam, #ab120687), dynasore (Abcam, #ab120192), cytochalasinD (Abcam, #ab143484), and methyl-β-cyclodextrin (Sigma, C4555-1G). CsCl was from Sigma

(12) Understanding Intracellular Biology to Improve mRNA Delivery by Lipid NanoparticlesSmall MethodsSeptember 1, 2023Morag Rose Hunter, Lili Cui, Benjamin Thomas Porebski, Sara Pereira, Silvia Sonzini, Uchechukwu Odunze, Preeti Iyer, Ola Engkvist, Rebecca Louise Lloyd, Samantha Peel, et al.to 10 μm; and 5-(N-ethyl-N-isopropyl)amiloride (EIPA; Sigma, cat. A3085-25MG), Dynasore (Abcam, cat. ab120192), and Pitstop2 (Abcam, cat. ab120687) up to 40 μm. MG-132 (Sigma, cat. 474791-1MG) and cyclohexamide

(13) Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 1The Journal of biological chemistryJuly 1, 2023Zhao X, Kiyozuka K, Konishi A, Kawabata-Iwakawa R, Minamishima YA, Obinata H.Cayman Chemical. Calcein-AM (#349-07201) was from Dojindo. Matrigel GFR (#354230) was from Corning. Dynasore (#ab120192) was from Abcam. Plasmid DNA constructs Plasmids encoding S1PR1-WT/-TM4/-R120A/-S5A-GFP were reported

(14) Differential intracellular trafficking of extracellular vesicles in microglia and astrocytesCellular and molecular life sciences : CMLSJune 30, 2023Pantazopoulou M, Lamprokostopoulou A, Karampela DS, Alexaki A, Delis A, Coens A, Samiotaki M, Kriebardis AG, Melki R, Pagakis SN, et al.without sEVs (200 ng/ml) for 6 h, 24 h, and 48 h (cultures were washed 24 h post-incubation). Dynasore (ab120192, Abcam, 80μΜ), methyl-β-cyclodextrin (C4555, Sigma, 250 μM), and cytochalasin D (PHZ1063, Invitrogen,

(15) Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survivalNature communicationsNovember 3, 2022Watson J, Ferguson HR, Brady RM, Ferguson J, Fullwood P, Mo H, Bexley KH, Knight D, Howell G, Schwartz JM, et al.2 μM ULK101 (Selleckchem, #S8793), 10 μM SBI0206965 (Selleckchem, #S7885), 10 μM Dynasore (Abcam, #ab120192), Monensin sodium salt, Na+ ionophore (Abcam, #ab120499) and 200 μM Primaquine bisphosphate (Sigma-Aldrich,

(16) Cell Surface Hsp90- and αMβ2 Integrin-Mediated Uptake of Bacterial Flagellins to Activate Inflammasomes by Human MacrophagesCellsSeptember 15, 2022Hoang TX, Kim JY.CA, USA); 17-AAG and radicicol from Cayman Chemical (Ann Arbor, MI, USA); dynamin inhibitor dynasore (ab120192), Dyngo® 4a (ab120689) from Abcam (Cambridge, UK). 2.2. Cell Culture The human monocytic cell line,

(17) Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagyMolecular PsychiatryApril 28, 2022Abdel Ali Belaidi, Shashank Masaldan, Adam Southon, Pawel Kalinowski, Karla Acevedo, Ambili T. Appukuttan, Stuart Portbury, Peng Lei, Puja Agarwal, Sue E. Leurgans, et al.(Cat# M2128) were purchased from Sigma Aldrich. The endocytosis inhibitors used were: Dynasore (Cat#ab120192, Abcam), Pitstop2 (Cat#ab144650, Abcam), cytochalasin D (Cat# C8273, Sigma Aldrich), filipin (Cat#F9765,

(18) Amyloid Beta Is Internalized via Macropinocytosis, an HSPG- and Lipid Raft-Dependent and Rac1-Mediated ProcessFrontiers in Molecular NeuroscienceFebruary 11, 2022Keyoumu Nazere, Tetsuya Takahashi, Naoyuki Hara, Kazuki Muguruma, Masahiro Nakamori, Yu Yamazaki, Hiroyuki Morino, Hirofumi Maruyamaand EHT1864, a Rac1 inhibitor of were purchased from Cayman chemical (Ann Arbor, MI, USA); dynasore (ab120192), a dynamin inhibitor was from Abcam (Cambridge, MA, USA), Alexa Fluor 488 transferrin and phalloidin

(19) Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearanceEMBO reportsFebruary 3, 2022Chen Y, Wu X, Zhang J, Pan G, Wang X, Guo X, Wang J, Cui X, Gao H, Cheng M, et al.metabolism in vivo. Materials and Methods Reagents and antibodies Pitstop2 (ab120687) and Dynasore (ab120192) were purchased from Abcam (Cambridge, UK). Actinomycin D (S8964), BAPTA‐AM (S7534), KN‐93 (S7423),

(20) Clathrin packets move in slow axonal transport and deliver functional payloads to synapsesNeuronSeptember 15, 2021Ganguly A, Sharma R, Boyer NP, Wernert F, Phan S, Boassa D, Parra L, Das U, Caillol G, Han X, et al.peptides, and recombinant proteins","Chemicals, peptides, and recombinant proteins" Dynasore,Abcam,Cat#ab120192 Latrunculin A,Life Technologies,Cat#L12370 Nocodazole,Millipore-Sigma,Cat#487928-10MG Swinholide

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Dynasore, dynamin inhibitor from Abcam

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Dynasore, dynamin inhibitor from Abcam

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