PP2, Src and RIP2 kinase inhibitor ab120308 from Abcam

Product Specs
ItemPP2, Src and RIP2 kinase inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120308
Quantity1 mg, 5 mg, 10 mg
Purity0.98
TypeInhibitor, inhibitor
Molecule NamePP2

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Csk-mediated Src family kinase regulation dampens neutrophil infiltration during pulmonary infectionJCI InsightJuly 22, 2025Wida Amini, Lena Schemmelmann, Jan-Niklas Heming, Marina Oguama, Katharina Thomas, Helena Block, Pia Lindental, Bernadette Bardel, Andreas Margraf, Oliver Soehnlein, et al.ratio of 1:10. Negative controls were kept on ice. Where indicated, PP2, a specific inhibitor of SFKs (ab120308, Abcam), or PP3, a negative control for PP2 (ab120617, Abcam), was used a dose of 10 μM (25). Neutrophils

(2) Coupling during collective cell migration is controlled by a vinculin mechanochemical switchProceedings of the National Academy of SciencesDecember 12, 2023T. Curtis Shoyer, Evan M. Gates, Jolene I. Cabe, Aarti N. Urs, Daniel E. Conway, Brenton D. Hoffmanthe droplet assay 72 h post-seeding. To inhibit Src kinase, cells were treated with 10 μM PP2 (Abcam ab120308) for 1 h. To inhibit Abl kinase, cells were treated with 50 μM Imatinib (Sigma SML1027) for 1 h. After treatment

(3) Mechanotransduction via Endothelial Adhesion Molecule CD31 Initiates Transmigration and Reveals a Role for Vascular Endothelial Growth Factor Receptor 2 in DiapedesisImmunityOctober 1, 2023Tao Fu, David P. Sullivan, Annette M. Gonzalez, Maureen E. Haynes, Prarthana J. Dalal, Nakisha S. Rutledge, Abigail L. Tierney, Julia A. Yescas, Evan W. Weber, William A. MullerScienetific,12350-039 Orbi Shaker Jr,Benchmark Scientific Inc.,BT302 "PP2, Src and RIP2 kinase inhibitor","Abcam, Inc.",ab120308 "PP3, Negative control for PP2","Abcam, Inc.",ab120617 Lipofectamine 2000,Thermo Fisher Scienetific,11668-027 AffiniPure

(4) Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesisBiomaterialsApril 1, 2018Xin Cui et al.(L6293, Sigma-Aldrich), VEGFR inhibitor cediranib (HY-10205, MedChemExpress LLC), Src inhibitor PP2 (ab120308, Abcam), PI3K inhibitor wortmannin (W1628, Sigma-Aldrich) and YAP inhibitor verteporfin (SML0534, Sigma-Aldrich).

(5) Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machineryeLifeDecember 22, 2017Chang TY, Chen C, Lee M, Chang YC, Lu CH, Lu ST, Wang DY, Wang A, Guo CL, Cheng PL.reagents: recombinant human BDNF was from PeproTech (Rocky Hill, NJ). PP2 (Src and RIP2 kinase inhibitor, ab120308), Dynole2–24 (potent dynamin I and II inhibitor; ab141290), and Dyngo 4a (ab120689; highly potent dynamin

(6) Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cellsOncotargetJuly 26, 2016Barcus CE, Keely PJ, Eliceiri KW, Schuler LA.ProteoChem (Indianapolis, IN). Inhibitors used for these studies were purchased as follows: PP-2 (#ab120308) from Abcam (Cambridge, MA), Dasatinib from Selleckchem (Boston, MA), pFAK Y397 inhibitors PF-573228

(7) Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor ActivationPloS oneJanuary 1, 2015Porcu G, Serone E, De Nardis V, Di Giandomenico D, Lucisano G, Scardapane M, Poma A, Ragnini-Wilson A.http://www.origene.com/mouse_dna/NM_001033481/MC223625/Gm98.aspx) was obtained from ORIGENE. The Src and RIP2 kinase inhibitor PP2 (ab120308) was from ABCAM. The retinoic x receptor inhibitor UVI3003 (TOCRIS Bioscience) was a gift from Dr. Enrico

(8) Manganese superoxide dismutase-mediated inside-out signaling in HaCaT human keratinocytes and SKH-1 mouse skinAntioxidants & redox signalingMay 20, 2014Holley AK, Xu Y, Noel T, Bakthavatchalu V, Batinic-Haberle I, St Clair DK.Methods Chemicals and antibodies The chemicals used in this study are as follows: PP2 (Abcam Biochemicals; ab120308); DHE (Molecular Probes; D1168); blasticidin (Invitrogen; R21001); puromycin (Clontech; 631305); polybrene

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PP2, Src and RIP2 kinase inhibitor from Abcam

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PP2, Src and RIP2 kinase inhibitor from Abcam

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