(R,S)-Rolipram, Selective PDE4 inhibitor from Abcam

Product Specs
Item(R,S)-Rolipram, Selective PDE4 inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120029
Quantity10 mg, 50 mg
Purity0.99
TypeInhibitor, inhibitor
Molecule NameRolipram

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Valerenic Acid and Pinoresinol as Positive Allosteric Modulators: Unlocking the Sleep-Promoting Potential of Valerian Extract Ze 911MoleculesMay 27, 2025Roman Senn, Lukas Schertler, Hendrik Bussmann, Juergen Drewe, Georg Boonen, Veronika Butterweckmodification: Instead of IBMX, the selective phosphodiesterase-4 inhibitor rolipram (Abcam, cat. no. ab120029) was used to prevent cAMP degradation [31]. The kit’s dilution buffer was prepared as a 1× working solution

(2) Nicotine Impairs Smooth Muscle cAMP Signaling and Vascular ReactivityMicrocirculationAugust 1, 2024Navid Singhrao, Victor A. Flores‐Tamez, Yumna A. Moustafa, Gopireddy R. Reddy, Abby E. Burns, Kent E. Pinkerton, Chao‐Yin Chen, Manuel F. Navedo, Madeline Nieves‐Cintrón(PDE3) or 4 (PDE4) inhibitors cilostamide (cilo, 100 nM, 231085) and rolipram (roli, 100 nM, Abcam ab120029), respectively, were added simultaneously with PE. Vessel tension was allowed to stabilize for 10 mins

(3) Optimized protocol to derive germline stem-cell-like cells from mouse pluripotent stem cellsSTAR protocolsSeptember 16, 2022Ishikura Y, Ohta H, Nagano M, Saitou M.,Life Technologies,15140148 Poly-L-Ornithine,Sigma,P3655 Progesterone,Sigma,P8783 Putrescine,Sigma,P5780 Recombinant Human BMP-4,R&D,314BP01M Recombinant Mouse SCF,R&D,455MC Rolipram,Abcam,AB120029 Sodium Pyruvate,Thermo Fisher Scientific,11360-070 Sodium Selenate,Sigma,S5261 STEM-CELLBANKER (GMP

(4) Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cellsThe EMBO journalJune 14, 2022Severino J, Bauer M, Mattimoe T, Arecco N, Cozzuto L, Lorden P, Hamada N, Nosaka Y, Nagaoka SI, Audergon P, et al.containing 100 ng/ml SCF (Peprotech, 250‐03), 10 µM forskolin (Sigma‐Aldrich, F3917), 10 µM rolipram (Abcam, ab120029), 2.5% FBS (Capricorn Scientific, FBSES12B), 10% KSR, 0.1 mM NEAA, 1 mM sodium pyruvate, 2 mM Glutamax

(5) The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanismsScientific reportsMarch 4, 2022Nelissen E, Possemis N, Van Goethem NP, Schepers M, Mulder-Jongen DAJ, Dietz L, Janssen W, Gerisch M, Hüser J, Sandner P, et al.Forskolin was purchased from Tocris Bioscience (#1099, Abingdon, UK), rolipram was purchased from Abcam (#ab120029), and sulfo-NHS-SS-biotin (#A39258) and streptavidin-coated Dynabeads (#65601) were purchased from Thermo Scientific

(6) Soluble Guanylate Cyclase Stimulator Vericiguat Enhances Long-Term Memory in Rats without Altering Cerebral Blood VolumeBiomedicinesAugust 19, 2021Ellis Nelissen, Elentina K. Argyrousi, Nick P. Van Goethem, Fuqiang Zhao, Catherine D. G. Hines, Gayathri Swaminath, Michael Gerisch, Joerg Hueser, Peter Sandner, Jos PrickaertsForskolin was purchased from Tocris Bioscience (#1099, Abingdon, UK), rolipram was purchased from Abcam (#ab120029, Cambridge, UK), and sulfo-NHS-SS-biotin (#21328) and streptavidin-coated Dynabeads (#65601) were purchased

(7) Chemical Stimulation of Rodent and Human Cortical Synaptosomes: Implications in NeurodegenerationCellsMay 12, 2021Faraz Ahmad, Yu Jing, Albert Lladó, Ping Liuwere procured from SigmaAldrich (St. Louis, MO, USA). Forskolin (HB1348) was from HelloBio. Rolipram (ab120029) and primary antibodies against PSD-95 (rabbit; ab18258) and GAPDH (mouse; ab8245) were from Abcam (Cambridge,

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(R,S)-Rolipram, Selective PDE4 inhibitor from Abcam

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(R,S)-Rolipram, Selective PDE4 inhibitor from Abcam

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