VCP Antibody PA5-22257 from Thermo Fisher Scientific

Product Specs
ItemVCP Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-22257
Quantity100 µL
ApplicationsImmunohistochemistry (Paraffin), Western Blot
Conjugate/TagUnconjugated
ReactivityCanine, Human, Mouse, Rat
TargetVCP
IsotypeIgG
HostRabbit
NCBI Gene AliasesFTDALS6, TERA, p97, CDC48, 3110001E05, p97/VCP
FormatPBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
ClonalityPolyclonal
NCBI Full Gene Namevalosin containing protein, valosin-containing protein
Concentration0.3 mg/mL
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human VCP. The exact sequence is proprietary
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulationiScienceNovember 19, 2021Guimei Yu, Yunpeng Bai, Kunpeng Li, Ovini Amarasinghe, Wen Jiang, Zhong-Yin Zhanganti-Flag,Sigma Aldrich,Cat # F1804; RRID: AB262044 Mouse polyclonal anti-VCP,Thermo Fisher,Cat # PA5-22257; RRID: AB11157831 ,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides, and recombinant

(2) ASL expression in ALDH1A1+ neurons in the substantia nigra metabolically contributes to neurodegenerative phenotypeHuman GeneticsOctober 1, 2021Shaul Lerner et al.Membranes were subsequently incubated with antibodies against ASL (1:500, ab97370, Abcam), p97 (1:10,000, PA5-22257, Thermo Scientific), GAPDH (1:1,0000, ab128915, Abcam), TH (1:500, CST-2792S, cell signaling) α-synuclein.

(3) ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus CoeruleusCell ReportsNovember 19, 2019Shaul Lerner et al.Membranes were subsequently incubated with antibodies against ASL (1:500, ab97370, Abcam), p97 (1:10,000, PA5-22257, Thermo Scientific), GAPDH (1:1,0000, ab128915, Abcam), TH (1:500, CST-2792S, cell signaling). Antibody

(4) Ubiquitin-proteasome system and ER stress in the brain of diabetic ratsJournal of cellular biochemistryApril 1, 2019Shruthi K, Reddy SS, Chitra PS, Reddy GB.

(5) VCP/p97 Is a Proviral Host Factor for Replication of Chikungunya Virus and Other AlphavirusesFrontiers in microbiologyJanuary 1, 2019Carissimo G, Chan YH, Utt A, Chua TK, Bakar FA, Merits A, Ng LFP.Santa Cruz Biotechnology, sc-57492, monoclonal against C-terminal), rabbit anti-VCP (1:500 dilution, Thermofisher, PA522257), mouse monoclonal anti-dsRNA (3 μg/mL dilution, Scicons, J2-1820), and rabbit anti-nsP1 or nsP2 or

(6) Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical SignaturesCellSeptember 6, 2018Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, Keshet R, Stettner N, Silberman A, Agemy L, et al.at room temperature. Membranes were subsequently incubated with antibodies against: p97 (1:10,000, PA5-22257, Thermo Scientific), GAPDH (1:1000, 14C10, #2118, Cell Signaling), CAD (1:1000, ab40800, Abcam and 1:500,

(7) PTEN counteracts FBXL2 to promote IP3R3- and Ca²⁺-mediated apoptosis limiting tumour growthNatureJune 22, 2017Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, Florens L, Washburn MP, Collazo-Lorduy A, Castillo-Martin M, et al.(Cell Signaling Technology no. 2920S), pAKT-S473 (Cell Signaling Technology no. 4058S), p97 (Thermo Scientific no. PA5-22257), p85|3 (AbCam no. ab28356), GFP (Cell Signaling Technology no. 2956S), CUL1 (Invitrogen no. 718700),

(8) Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replicationNature communicationsOctober 17, 2016Wu KX, Phuektes P, Kumar P, Goh GY, Moreau D, Chow VT, Bard F, Chu JJ.and cross-reacts with CA16. Rabbit polyclonal anti-CDK6 (PA5-27978, IF 1:200; WB 1:500) and anti-VCP (PA5-22257, IF 1:200) were obtained from Pierce, ThermoScientific. Mouse monoclonal anti-AURKB (ab3609, WB 1:1000),

(9) Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesisNatureNovember 19, 2015Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, et al.incubated with antibodies against ASS1 (1:500, sc-99178, Santa Cruz Biotechnology)22, p97 (1:10,000, PA5-22257, Thermo Scientific), GAPDH (1:1000, 14C10, #2118, Cell Signaling)23, CAD (1:1000, ab40800, abcam)24,

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VCP Antibody from Thermo Fisher Scientific

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