NLRP6 Antibody PA5-21022 from Thermo Fisher Scientific

Product Specs
ItemNLRP6 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-21022
Quantity100 µg
ApplicationsImmunohistochemistry, Western Blot
Conjugate/TagUnconjugated
ReactivityHuman
TargetNLRP6
HostRabbit
NCBI Gene AliasesAVR, CLR11.4, NALP6, NAVR, NAVR/AVR, PAN3, PYPAF5
FormatPBS with 0.02% sodium azide
ClonalityPolyclonal
NCBI Full Gene NameNLR family pyrin domain containing 6
Concentration1 mg/mL
ImmunogenA 16 amino acid peptide near the amino terminus of human NALP6
IsotypeIgG
Storage TemperatureMaintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageMaintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

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(1) NLRP6 governs hippocampal microglial phagocytosis to resist stress-induced depressive-like behaviors in mice and the intervention effect of bezafibrateJournal of Advanced ResearchAugust 26, 2025Fan Yang, Xiuqin Kong, Yuefeng Hu, Wanzhao Liu, Pengfei Xie, Yuexi Gu, Yan Zhang, Yili Yang, Chuanfeng Tang, Jianmei Liwere blocked in 3 % BSA for 1 h, then incubated overnight at 4 °C with primary antibodies: anti-NLRP6 (PA5-21022; Invitrogen; rabbit), anti-CD36 (bs-8873R; Bioss; rabbit), and anti-GAPDH (AF0006; Beyotime; mouse).

(2) NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancerCell death & diseaseOctober 21, 2022Rao X, Zhou X, Wang G, Jie X, Xing B, Xu Y, Chen Y, Li J, Zhu K, Wu Z, et al.anti-CD68 (1:100; #ab201973; Abcam), anti-CD206 (1:2000; #ab252921; Abcam), and anti-NLRP6 (1:100; #PA5-21022; Invitrogen). Three fields were randomly chosen from each slide, and the number of CD68- or CD206-positive

(3) Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acidsMicrobiomeJune 29, 2019Li JM, Yu R, Zhang LP, Wen SY, Wang SJ, Zhang XY, Xu Q, Kong LD.Abcam), rabbit anti-occludin (ab168986, Abcam), rabbit anti-ZO-1 (H-300, Santa Cruz), rabbit anti-NLRP6 (PA5-21022, Thermo Fisher Scientific), rabbit anti-caspase-1 (sc-514, Santa Cruz), rabbit anti-NLRP3 (#15101, CST),

(4) Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6The Journal of allergy and clinical immunologyOctober 1, 2017Hua X, Yuan X, Li Y, Chen H, Yuan J, Tanumiharjo S, Bian F, Su L, Hong Y, Liu Y, et al.

(5) Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eyeJournal of autoimmunityJune 1, 2017Chi W, Hua X, Chen X, Bian F, Yuan X, Zhang L, Wang X, Chen D, Deng R, Li Z, et al.(NBP1-77080), caspase-1 (NB100-56565), caspase 8 (NB100-56116, Novus Biologicals, Littleton, CO), NLRP6 (PA5-21022), IL-1β (P420B), BRCC36 (PA5-20426, Thermo Scientific, Rochford, IL), ASC (N-15, SC-22514R), IL-18 (SC-6179,

IHC