LDLR Antibody PA5-22976 from Thermo Fisher Scientific

Product Specs
ItemLDLR Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-22976
ApplicationsWB, ICC, IHC-p
ReactivityHu, Ms
Concentration1 mg/mL
ImmunogenSynthetic peptide made to an internal portion of the human LDL Receptor protein (within residues 500-550)
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles
IsotypeIgG
NCBI Full Gene Namelow density lipoprotein receptor
ClonalityPolyclonal
FormatPBS with 0.02% sodium azide
NCBI Gene AliasesFH, LDLCQ2, FHCL1, FHC, Hlb301
HostRabbit
TargetLDLR
Conjugate/TagUnconjugated
Quantity100 µL

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Nherf family PDZ scaffold protein 2 (Nherf2) is a major determinant of bile acid pool dynamics and contributes to regulation of Western diet-induced obesityAmerican Journal of Physiology-Cell PhysiologyDecember 1, 2025Dachuan Dong, Wen-Jun Shen, Stefanie Bittner, Jia Chen, Xiao Hao, Mark Donowitz, Fredric B. Kraemer, Salman Azharfollows: Nherf1 (Thermo Fisher Scientific, Cat. #PA1–090, 1:1000), LDLR (Thermo Fisher Scientific, Cat. # PA5–22976) Nherf2 (Cell Signaling Technology, Cat. #9568, 1:1000), SR-B1 (homemade, 1:500), and β-actin (Novus Biologicals

(2) The Functional Interaction Between PRDM16 and the SREBP Pathway Controls Lipid MetabolismInternational Journal of Molecular SciencesOctober 22, 2025Hafiz Majid Mahmood, Maria Teresa Bengoechea-Alonso, Dana E. Al-Ansari, Khaled Machaca, Johan EricssonMN, USA). Anti-FLAG (F3165) antibody was obtained from Merck Millipore. The LDL receptor antibody (PA5-22976) was purchased from Thermo Fisher Scientific, and the β-actin antibody (A5441) was purchased from Merck Millipore

(3) Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr(-/-) MiceCellsDecember 22, 2022Sreekumar PG, Su F, Spee C, Araujo E, Nusinowitz S, Reddy ST, Kannan R.Newark, CA, USA) for 30 min. Cells were incubated overnight with 1:100 dilution of LDLR antibody (# PA5-22976, Invitrogen, Carlsbad, CA, USA) and for 30 min with FITC-labeled secondary antibodies. Samples were

(4) Exenatide prevents statin-related LDL receptor increase and improves insulin secretion in pancreatic beta cells (1.1E7) in a protein kinase A-dependent mannerJournal of applied biomedicineDecember 1, 2022Buldak L, Machnik G, Skudrzyk E, Boldys A, Maliglowka M, Kosowski M, Basiak M, Buldak RJ, Okopien B.

(5) Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and PharmacokineticsCancersJune 16, 2022Taiarol L, Bigogno C, Sesana S, Kravicz M, Viale F, Pozzi E, Monza L, Carozzi VA, Meregalli C, Valtorta S, et al.(MA1-16757, 1:5000), VLDLR (MA5-24790, 1:1000), ABCA1 (PA1-16789, 1:500), LRP1 (MA1-27198, 1:500), and LDLR (PA5-22976, 1:1000) purchased from ThermoFisher. Membranes were incubated with secondary anti-rabbit antibody (A0545,

(6) The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trialCancer & metabolismNovember 23, 2020Feldt M, Menard J, Rosendahl AH, Lettiero B, Bendahl PO, Belting M, Borgquist S.Protran, GE Healthcare) blocked in 5% milk TBS-T and probed overnight (4 °C) with anti-LDLR (0,5 μg/ml, PA5-22976, Thermo Fisher Scientific, IL, USA) and anti-GAPDH (1:1000, MAB374, Merck-Millipore, Darmstadt, Germany)

(7) Development of an LDL Receptor-Targeted Peptide Susceptible to Facilitate the Brain Access of Diagnostic or Therapeutic AgentsBiologyJuly 11, 2020André S, Larbanoix L, Verteneuil S, Stanicki D, Nonclercq D, Vander Elst L, Laurent S, Muller RN, Burtea C.0.3% Triton X-100 (Sigma-Aldrich). LDLR was detected using the anti-LDLR antibody made in rabbit (# PA5-22976, recognizing residues 500–550 of human and mouse LDLR that present a 92% identity, and both glycosylated

(8) Dysregulated Lipid Transport Proteins Correlate With Pathogenesis and Outcome in Severe Alcoholic HepatitisHepatology communicationsDecember 1, 2019Maras JS, Das S, Bhat A, Kumar Vyas A, Yadav G, Chaudhary S, Sukriti S, Gupta AC, Bihari C, Mahiwall R, et al.

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LDLR Antibody

LDLR Antibody from Thermo Fisher Scientific

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LDLR Antibody from Thermo Fisher Scientific

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