NLRP3 Antibody PA5-20838 from Thermo Fisher Scientific

Product Specs
ItemNLRP3 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-20838
FormatPBS with 0.02% sodium azide
ClonalityPolyclonal
NCBI Full Gene NameNLR family pyrin domain containing 3, NLR family, pyrin domain containing 3
ApplicationsWB, ICC
ReactivityHu, Ms
Concentration1 mg/mL
ImmunogenA 16 amino acid peptide from near the amino terminus of human NALP3
Storage TemperatureMaintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageMaintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
IsotypeIgG
NCBI Gene AliasesMWS, AGTAVPRL, CLR1.1, CIAS1, FCU, FCAS, C1orf7, Mmig1, AVP, KEFH, DFNA34, NALP3, AII, Pypaf1, AII/AVP, Cias1, FCAS1, PYPAF1
HostRabbit
TargetNLRP3
Conjugate/TagUnconjugated
Quantity100 µg

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(1) Multiwalled carbon nanotubes activate the NLRP3 inflammasome-dependent pyroptosis in macrophagesMolecular PharmacologyMay 1, 2025Chol Seung Lim, Ja Kook Gu, Qiang Marabbit anti-GSDMD-N-term (1:100, Abcam, ab215203), rabbit anti-NLRP3 (1:100, Thermo Fisher Scientific, PA520838), or mouse anti-ASC (1:50, Santa Cruz Biotechnology, sc-514414) antibodies in blocking buffer for overnight

(2) Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral PathogenesisMicrobiology spectrumMarch 28, 2023Anand A, Chandana M, Ghosh S, Das R, Singh N, Vaishalli PM, Gantasala NP, Padmanaban G, Nagaraj VA.14-6731-81), anti-mouse phospho-NF-κB p65 (Ser536; Invitrogen, MA5-15160), anti-mouse NLRP3 (Invitrogen, PA5-20838), anti-mouse phospho-NLRP3 (Ser295; Invitrogen, PA5-105071), anti-mouse cleaved caspase-1 (Asp296; Cell Signaling Technology

(3) Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuriesFrontiers in immunologyJanuary 1, 2023Chen X, Guo J, Mahmoud S, Vanga G, Liu T, Xu W, Xiong Y, Xiong W, Abdel-Razek O, Wang G.Santa Cruz Biotechnology, Dallas, Texas), or cleaved caspase-1(#89332, Cell Signaling Technology), or NLRP3 (# PA5-20838, Thermo Scientific, Rockford, IL), or GSDMD (ab209845, Abcam Inc, Cambridge, MA), or ASC (#67824, Cell Signaling Technology

(4) The Enhancer-Binding Protein MifR, an Essential Regulator of α-Ketoglutarate Transport, Is Required for Full Virulence of Pseudomonas aeruginosa PAO1 in a Mouse Model of PneumoniaInfection and immunityOctober 20, 2022Xiong W, Perna A, Jacob IB, Lundgren BR, Wang G.

(5) Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in miceNature communicationsJuly 12, 2022Chandana M, Anand A, Ghosh S, Das R, Beura S, Jena S, Suryawanshi AR, Padmanaban G, Nagaraj VA.(Thermo Fisher Scientific, MA5-15160; 1:1000 dilution); anti-mouse NLRP3 (Thermo Fisher Scientific, PA5-20838; 1:1000 dilution); anti-mouse Phospho-NLRP3 (Ser295) (Thermo Fisher Scientific, PA5-105071; 1:1000 dilution);

(6) Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axisBMC pulmonary medicineApril 26, 2022Fu Z, Wu X, Zheng F, Zhang Y.adequate length), and incubated successively with the primary antibody(rabbit anti-NLRP3 antibody: #PA5-20838, rabbit anti-cleaved caspase-1 antibody: #PA5-77886, rabbit anti-GAPDH antibody: #PA1-987, Invitrogen,

(7) Modafinil Reduces Neuronal Pyroptosis and Cognitive Decline After Sleep DeprivationFrontiers in neuroscienceJanuary 1, 2022Xiong X, Zuo Y, Cheng L, Yin Z, Hu T, Guo M, Han Z, Ge X, Li W, Wang Y, et al.powder) for 2 h. The membrane was incubated overnight with NLRP1 (1:1,000; ab98181; Abcam), NLRP3 (1:250; PA5-20838; Thermo Fisher Scientific), NLRC4 (1:1,000; 06-1125; MilliporeSigma), GSDMD (1:1,000; ab209845; Abcam),

(8) Role of Surfactant Protein D in Experimental Otitis MediaJournal of innate immunityJanuary 1, 2021Abdel-Razek O, Liu T, Chen X, Wang Q, Vanga G, Wang G.(1:200; gift from Dr. Wright; Duke University Medical Center, Durham, NC, USA), or anti-NLRP3 antibody (PA5-20838; Thermo Scientific) or anti-p-NF-κB p65 (#3033; Cell Signaling Technology [CST], Boston, MA, USA) antibodies

(9) TRIM31 inhibits NLRP3 inflammasome and pyroptosis of retinal pigment epithelial cells through ubiquitination of NLRP3Cell biology internationalNovember 1, 2020Huang P, Liu W, Chen J, Hu Y, Wang Y, Sun J, Feng J.

(10) Surfactant Protein D Dampens Lung Injury by Suppressing NLRP3 Inflammasome Activation and NF-κB Signaling in Acute PancreatitisShock (Augusta, Ga.)May 1, 2019Yu J, Ni L, Zhang X, Zhang J, Abdel-Razek O, Wang G.antibody (Dr. Jo Rae Wright of the Duke University Medical Center for mouse SP-D Ab), Anti-NLRP3 antibody (PA5–20838, Thermo Scientific), antibody p-IκB-α (#2859, Cell Signaling Technology (CST), Boston, MA), p-NF-κB

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NLRP3 Antibody from Thermo Fisher Scientific

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NLRP3 Antibody from Thermo Fisher Scientific

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