Phospho-AMPKalpha1 (Ser485) (45F5) Rabbit mAb 2537S from Cell Signaling Technology

Product Specs
ItemPhospho-AMPKalpha1 (Ser485) (45F5) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number2537S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargetAMPK-alpha1 (Ser496) phosphate
ModificationsAMPK-alpha1 (Ser496) phosphate
HostRabbit
NCBI Gene AliasesAMPK, AMPK alpha 1, AMPKa1
ClonalityMonoclonal
NCBI Full Gene Nameprotein kinase AMP-activated catalytic subunit alpha 1
Research AreaMetabolism
IsotypeIgG
Clone45F5
Molecular Weight62 kDa

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Eupatilin-derived compounds enhance antitumor activity and doxorubicin efficacy in triple-negative breast cancerFront OncolAugust 12, 2026Choong-Jae Lee, Jinyoung Park, Yanghee Choi, Sung Hoon Sim, Sun-Young Kong(Cell Signaling #17366, 1:1,000), anti-AMPK (Cell Signaling #2795, 1:1,000), anti-phospho-AMPK (Cell Signaling #2537, 1:1,000) and anti-β Actin (INVITROGEN #MA1-140, 1:5,000). 2.9 Gene expression analysis by RT-qPCR Cells

(2) Alternol-Induced Oxidative Modification of SQSTM1/p62 Is Associated with Nrf2 Signaling and Autophagy-Related Responses in Prostate Cancer CellsAntioxidants (Basel)June 22, 2026Wang Liu, Jiang Zhao, Changlin Li, Haixia Xu, Ruibao Chen, Xing Zeng, Jun Yang, Cuncong Zhong, Xiangwei Wang, Benyi LiCaspase-3 (CST-9662), LC3β (CST-3868), AMPK (CST-5831), p-AMPK (T172) (CST-2535), p-AMPK(S485) (CST-2537), KEAP1 (CST-8047), Nrf2 (CST-12721), p-LKB1/S428 (CST-3482), phospho-SQSTM1/p62 (Ser403) (CST-39786),

(3) Fatty acid‑activated proton transporter SR4 prevents hepatic steatosis and metabolic alterations in diabetic mice by improving mitochondria function, energy balance and oxidative stressExperimental and Therapeutic MedicineMay 20, 2026James Figarola, Jyotsana Singhal, Sharad Singhalantibodies against total and phosphorylated AMPK and total and phosphorylated ACC (cat. nos. 2532, 2537, 8578 and 3661; Cell Signaling Technology, Inc.). After a series of washes, the membranes were stained

(4) Eight-week dietary methionine restriction does not impair resistance exercise-induced mTORC1 signalling activation in ratsBiochemistry and Biophysics ReportsMarch 1, 2026Naoki Fukao, Mito Watanabe, Ryo Takagi, Koki Okumura, Naomi Yoshii, Koma Kawabata, Satoshi FujitaPhospho-Akt Thr308 (#13038, CST), Phospho-Akt Ser473 (#9271, CST), AMPKα (#2532, CST), Phospho-AMPKα Thr172 (#2537, CST), ULK1 (#8054, CST), Phospho-ULK1 Ser317 (#12753, CST), LC3B (#2775, CST), p62 (#PM045, Medical

(5) Effect and Mechanisms of Yiqi Jianpi Xiaoyu Prescription on Kidney Fibrosis on the Basis of Metabolomics and Experimental ValidationFood science & nutritionNovember 1, 2025Lu K, Ye L, Jiang W, Cheng T, Xia H, Zhang P, Zhang B.27,987, Cell Signaling), anti‐AMPK antibody (1:1000, 2535, Cell Signaling), anti‐p‐AMPK antibody (1:1000, 2537, Cell Signaling), and anti‐GAPDH antibody (1:1000, AF4718, Affinity). 2.13 Metabolomic Analysis Plasma

(6) Effect and Mechanisms of Yiqi Jianpi Xiaoyu Prescription on Kidney Fibrosis on the Basis of Metabolomics and Experimental ValidationFood Sci NutrOctober 29, 2025Keda Lu, Liqing Ye, Wenze Jiang, Tianyang Cheng, Hong Xia, Peipei Zhang, Bingbing Zhang27,987, Cell Signaling), anti‐AMPK antibody (1:1000, 2535, Cell Signaling), anti‐p‐AMPK antibody (1:1000, 2537, Cell Signaling), and anti‐GAPDH antibody (1:1000, AF4718, Affinity). 2.13 Metabolomic Analysis Plasma

(7) BRD4 Inhibitor Alleviates Recurrent Spontaneous Abortion via Regulating BRD4/STAT3/IL-17A Axis to Decrease the Th17 Cell DifferentiationReprod Med BiolOctober 15, 2025Fen Liu, Zhenhui Zhang, Chengying Yang9139, CST, USA), p‐STAT3 (1:1000, 9131S, CST, USA), BRD4 (1:1000, 54615, CST, USA), p‐AMPK‐α1 (1:1000, 2537, CST, USA), AMPK‐α1 (1:1000, 2532, CST, USA), SREBP‐1c (1:500, ab28481, Abcam, USA), and ACC‐1 (1:10 000

(8) POSTN‐Mediated Interplay of M1 Polarized Macrophage with Tendon‐Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?Advanced ScienceAugust 18, 2025Hang Liu, Xinyue Li, Mengyi Li, Ziyang Sun, Xu Wang, Juehong Li, Binbin Xu, Qian Chen, Cunyi Fan, Hongjiang RuanThe MCAD (Cat# A4567) antibody was purchased from Abclonal (Wuhan, China). The anti‐AMPK‐pS485 (Cat# 2537), anti‐AMPK (Cat# 2532), anti‐ACC (Cat# 3676), and anti‐ACC‐pS79 (Cat# 11 818) were purchased from Cell Signaling Technology

(9) The swine acute diarrhea syndrome coronavirus spike protein promotes syncytial formation via upregulation of cellular cholesterol synthesismBioAugust 13, 2025Dakai Liu, Miaomiao Zeng, Jiyu Zhang, Liaoyuan Zhang, Hongyan Shi, Xin Zhang, Jialin Zhang, Jianfei Chen, Zhaoyang Ji, Xiuwen Li, et al.phosphorylated (p)-AKT (Ser473) (4058T), p-AMPK alpha (Thr172) (2535S), and p-AMPK alpha (Ser485) (2537S) were obtained from Cell Signaling Technology (Danvers, MA, USA). Abs against PP2A alpha (A6702), HMGCR

(10) Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathwayAlzheimers Res TherJune 23, 2025Chunyan Ma, Yutong Ye, Xinyu Shi, Na Li, Zhiming Mu, Tao Tan, Huijuan Yin, Jianwu Dai, Yi Liu, Hongli ChenkDa),BIOSS (BS-10296R),1:800 Occludin (59 kDa),Proteintech (27260–1-AP),1:20000 p-AMPK (62 kDa),CST (2537 s),1:1000 Aβ (87 kDa),BOSTRR (MA00081),1:2000 Bax (21 kDa),BOSTER (BM3964),1:1000 Bcl-2 (26 kDa),Proteintech

(11) The effects of different intensities of aerobic exercise for 8 weeks on neurogenesis, depression, and anxiety in young miceJournal of Korean Biological Nursing ScienceMay 30, 2025Mi Yang Jeon, Quan Feng Liu, Chi Yang Yoon, Bong Gyu Kim, Ji Hyun Kim, Ha Jin Jeong, Songhee Jeontotal ERK1/2 (1:3,000, #9102), p-CREB (1:1,000, #9198), total CREB (1:1,000, #9197), p-AMPK (1:1,000, #2537), total AMPK (1:1,000, #2532), p-PSD95 (1:1,000, #45737), and total PSD95 (1:1,000, #3409) from Cell Signaling Technology

(12) Octanoic acid-rich diet alleviates breast cancer-induced bone pain via the acyl-ghrelin/NPY pathwayThe Korean Journal of PainApril 1, 2025Longjie Xu, Lili Hou, Chun Cao, Xiaohua LiThermo Fisher Scientific), NPY (sc-133080, Santa), mTOR (#2983, CST), p-mTOR (#5536, CST), AMPK (#2603, CST), p-AMPK (#2537, CST), CaMKKβ (#16810, CST), GOAT (bs-13355R, Bioss), and β-Actin (#4967, CST). 14. Statistical analysis The

(13) Design, Synthesis and Evaluation of Novel Cyclopropanesulfonamide Derivatives for the Treatment of EGFRC797S Mutation in Non-Small Cell Lung CancerDrug Design, Development and TherapyFebruary 27, 2025Mengxuan Wang, Zhenhong Xia, Wenyan Nie, Chunlong Wang, Haoran Nie, Shuai Zhang, Jiaqi Qiu, Yang Yang, Cuifang Yao, Ling Xu, et al.affinity), P-PI3K (1:1000; AF3242, affinity), AMPK (1:1000; 9158, Cell signaling), P-AMPK (1:1000; 2537, Cell signaling), β-actin (1:1000;A5441, Sigma). Full and uncropped Western blots are presented in Figure

(14) Design, Synthesis and Evaluation of Novel Cyclopropanesulfonamide Derivatives for the Treatment of EGFRC797S Mutation in Non-Small Cell Lung CancerDrug Des Devel TherFebruary 27, 2025Mengxuan Wang, Zhenhong Xia, Wenyan Nie, Chunlong Wang, Haoran Nie, Shuai Zhang, Jiaqi Qiu, Yang Yang, Cuifang Yao, Ling Xu, et al.affinity), P-PI3K (1:1000; AF3242, affinity), AMPK (1:1000; 9158, Cell signaling), P-AMPK (1:1000; 2537, Cell signaling), β-actin (1:1000;A5441, Sigma). Full and uncropped Western blots are presented in Figure

(15) Autophagic flux-lipid droplet biogenesis cascade sustains mitochondrial fitness in colorectal cancer cells adapted to acidosisCell Death DiscovJanuary 25, 2025Xiaojie Liu, Xue Sun, Wenqing Mu, Yanan Li, Wenqing Bu, Tingting Yang, Jia Zhang, Rui Liu, Jiayu Ren, Jin Zhou, et al.(ab110411), PGC-1α (ab77210), Ki-67 (ab15580) were purchased from Abcam. Anti-phospho-AMPKα (Ser485) (2537), Anti-AMPKα (5831), Anti-GAPDH (5174 s), Anti-rabbit IgG (7074S) were from Cell Signaling Technology.

(16) Ameliorative effects of Asiasarum root and rhizome extract on high fat diet‑induced obesity in mice through regulation of the SIRT1/PGC1α/AMPK pathways in muscle and liver tissuesMolecular Medicine ReportsJanuary 24, 2025Chenzi Lyu, Seok Yong Kang, Haifeng Shao, Dongeun Kim, Hyo Won Jung1:1,000; cat. no. 69432), phosphorylated (p)-AMP-activated protein kinase (AMPK; 1:1,000; cat. no. 2537) and AMPK (1:1,000; cat. no. 2532) were purchased from Cell Signaling Technology, Inc. Antibodies against

(17) Fibronectin type III domain containing protein 5/irisin alleviated sepsis-induced acute kidney injury by abating ferroptosis through the adenosine 5'-monophosphate-activated protein kinase/nuclear factor erythroid-2-related factor 2 signaling pathwayCytojournalNovember 25, 2024Shenghao Gui, Chaochao Zhu, Yunfeng Luprimary antibodies were FNDC5 (1:1000, ab174833, Abcam, Cambridge, UK), phospho-AMPK (p-AMPK, 1:1000, 2537, CST, MA, USA), AMPK (1:1000, 2532, CST, MA, USA), nuclear factor erythroid-2-related factor 2 (Nrf2,

(18) Fibronectin type III domain containing protein 5/irisin alleviated sepsis-induced acute kidney injury by abating ferroptosis through the adenosine 5'-monophosphate-activated protein kinase/nuclear factor erythroid-2-related factor 2 signaling pathwayCytojournalNovember 25, 2024Shenghao Gui, Chaochao Zhu, Yunfeng Luprimary antibodies were FNDC5 (1:1000, ab174833, Abcam, Cambridge, UK), phospho-AMPK (p-AMPK, 1:1000, 2537, CST, MA, USA), AMPK (1:1000, 2532, CST, MA, USA), nuclear factor erythroid-2-related factor 2 (Nrf2,

(19) Ginsenoside Rg1 Alleviates Blood–Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive AutophagyAntioxidants (Basel)November 24, 2024Shanshan Yang, Zihao Fang, Hongwei Duan, Weitao Dong, Longfei Xiaoconducted as previously described [32]. The primary antibodies against p-AMPK (Ser485) (1:1000 dilution; #2537; Cell Signaling Technology, Danvers, MA, USA), AMPK (Ser485) (1:1000 dilution; #2532; Cell Signaling Technology

(20) Elevated meteorin-like protein from high-intensity interval training improves heart function via AMPK/HDAC4 pathwayGenes & DiseasesNovember 1, 2024Yongshun Wang, Jie Yuan, Huadong Liu, Jie Chen, Jieru Zou, Xiaoyi Zeng, Lei Du, Xin Sun, Zhengyuan Xia, Qingshan Geng, et al.ab235775, Abcam), GLUT4 (Cat # 2213, Cell Signaling Technology), phosphorylated AMPK (p-AMPK; Cat # 2537, Cell Signaling Technology), AMPK (Cat # 2532, Cell Signaling Technology), p-HDAC4 (Cat # 3424, Cell Signaling Technology

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Phospho-AMPKalpha1 (Ser485) (45F5) Rabbit mAb

Phospho-AMPKalpha1 (Ser485) (45F5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-AMPKalpha1 (Ser485) (45F5) Rabbit mAb from Cell Signaling Technology

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