NDRG1 (D6C2) Rabbit mAb 9408S from Cell Signaling Technology

Product Specs
ItemNDRG1 (D6C2) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number9408S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetNDRG1
HostRabbit
NCBI Gene AliasesCAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
ClonalityMonoclonal
NCBI Full Gene NameN-myc downstream regulated 1
Research AreaDevelopmental Biology
IsotypeIgG
CloneD6C2
Molecular Weight46, 48

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) The lifespan-extending MEK1 inhibitor trametinib promotes regulation of de novo lipogenesis enzymes by chaperone-mediated autophagyFront AgingJanuary 1, 2025Chen J, Berg J, Burns CM, Jia H, Li X, Miller RA, Endicott SJ, Garcia G.(Boster:P00135), S6 (CST:2217), pS6 pS235/236 (CST:4857), 4EBP1 (CST:9644), p4EBP1 pT37/46 (CST:2855), NDRG1 (CST:9408), pNSRG1 pT346 (CST:5482). Cell culture and trametinib-treated mice For all cell culture experiments,

(2) AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanismsCell Chemical BiologyDecember 1, 2023Johnny Castillo Castillo Cabrera, Hong Dang, Adam Graves, Zhigang Zhang, Jose Torres-Castillo, Kelin Li, Zayna King, Pengda Liu, Jeff Aubé, James E. Bear, et al.50494S phosphor-NDRG1 Thr346,Cell Signaling Technologies,Cat# 5482 NDRG1,Cell Signaling Technologies,Cat# 9408 GAPDH,Cell Signaling Technologies,Cat# 5174S b-Tubulin,Cell Signaling Technologies,Cat# 2146S Lamin

(3) Targeted suppression of mTORC2 reduces seizures across models of epilepsyNature CommunicationsNovember 14, 2023James Okoh, Jacqunae Mays, Alexandre Bacq, Juan A. Oses-Prieto, Stefka Tyanova, Chien-Ju Chen, Khalel Imanbeyev, Marion Doladilhe, Hongyi Zhou, Paymaan Jafar-Nejad, et al.p-PKC (S657, 1:2000 #9371), p-NDRG1 (T346, 1:1000 #3217), PKCα (1:1000 #2056), Total-NDRG1 (1:1000 #9408) Total-S6 (1:1000, #2217), Total-Akt (1:1000 #9272), GFP (1:1, 000 #2956), HA (1:1000 #3734) and β-actin

(4) NDRG1 is induced by antigen-receptor signaling but dispensable for B and T cell self-toleranceCommunications biologyNovember 10, 2022Hodgson R, Xu X, Anzilotti C, Deobagkar-Lele M, Crockford TL, Kepple JD, Cawthorne E, Bhandari A, Cebrian-Serrano A, Wilcock MJ, et al.and probed with indicated antibodies. Antibodies; anti-NDRG1 D6C2 mAb (Cell Signaling Technologies; #9408, 1:1000) and anti-rabbit IgG, HRP-linked antibody (Cell Signaling Technology; #7074). Monoclonal anti-β-actin-peroxidase

(5) A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor developmentScience advancesAugust 5, 2022Benedetti V, Banfi F, Zaghi M, Moll-Diaz R, Massimino L, Argelich L, Bellini E, Bido S, Muggeo S, Ordazzo G, et al.Cell Signaling Technology, 37259), anti-NDRG1 (1:1000; clone D6C2, rabbit; Cell Signaling Technology, 9408), anti–signal transducer and activator of transcription 3 (STAT3) (1:1000; clone 124H6, mouse; Cell Signaling Technology

(6) Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinaseCell ReportsOctober 5, 2021Ben Zhou, Yuyao Zhang, Sainan Li, Lianfeng Wu, Geza Fejes-Toth, Aniko Naray-Fejes-Toth, Alexander A. Soukas,Cell Signaling Technology,Cat# 5482; RRID:AB_10693451 Rabbit monoclonal anti-NDRG1 (D6C2),Cell Signaling Technology,Cat# 9408; RRID:AB_11140640 Rabbit monoclonal anti-Raptor (24C12),Cell Signaling Technology,Cat# 2280; RRID:AB_561245 Rabbit

(7) ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through AutophagyCell ReportsJanuary 5, 2021Jae-Sung You, Nilmani Singh, Adriana Reyes-Ordonez, Nidhi Khanna, Zehua Bao, Huimin Zhao, Jie ChenCytochrome c (4272), pSer473-Akt (9271), pThr308-Akt (9275), Akt (9272), pThr346-NDRG1 (3217), NDRG1 (9408), LC3A/B (4108), p62 (23214), RhoA (2117), and GAPDH (2118) from Cell Signaling Technology; anti-pSer657-PKCα

(8) NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational RepressionMolecular and Cellular BiologyJune 29, 2020Tsuyoshi Waku, Hiroyuki Katayama, Miyako Hiraoka, Atsushi Hatanaka, Nanami Nakamura, Yuya Tanaka, Natsuko Tamura, Akira Watanabe, Akira Kobayashianti-␣-tubulin (DM1A; Sigma-Aldrich), anti-NFE2L1 (D5B10; Cell Signaling Technology), anti-NFE2L3 (9408), anti-FLAG (M2; Sigma-Aldrich), and normal rabbit IgG (Wako). A monoclonal NFE2L3 antibody (9408) raised

(9) Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency.Nature MedicineNovember 1, 2019Chien-Ju Chen et al.(Ser657, 1:2000, #9371) total PKCα (1:1000 #2056), p-NDRG1 (1:1000, Thr346, #3217), total NDRG1 (1:1000 #9408) were purchased from Cell Signaling and Technology Laboratories (Danvers, MA) and β-actin (1:5000 #1501)

(10) Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion LymphomamBioFebruary 26, 2019Carolina Caro-Vegas, Aubrey Bailey, Rachele Bigi, Blossom Damania, Dirk P. DittmerSer473 D93 XP (no. 4060), AKT pan-11E7 (no. 4685), phospho-NDGR1 Thr346 (no. 3217), NDRG1 D6C2 (no. 9408), cleaved caspase-3 Asp175 (no. 9664), and cleaved PARP Asp214 D64E10 XP (no. 5625) from Cell Signaling

(11) Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibitionScience signalingFebruary 26, 2019Katsuno Y, Meyer DS, Zhang Z, Shokat KM, Akhurst RJ, Miyazono K, Derynck R.Signaling, Cat#), anti-phospho-NDRG1-Thr346 (Cell Signaling, Cat# 3217), anti-NDRG1 (Cell Signaling, Cat# 9408) and anti-GAPDH (Sigma Aldrich, Cat# G8795). Quantitative real-time PCR measurements of mRNA. Total

(12) Sex differences in lifespan extension with acarbose and 17‐α estradiol: gonadal hormones underlie male‐specific improvements in glucose tolerance and mTORC 2 signalingAging CellDecember 1, 2017Michael Garratt, Brian Bower, Gonzalo G. Garcia, Richard A. MillerFOXO1: 2880; pFOXO1 T24: 9464; total S6: 2217; pS6: 2211; p4EBP1: 2855; total 4EBP1: 9644; total NDRG1: 9408; pNDRG1: 5482 – www.cellsignal.com), Santa Cruz (pSGK1: 16745 – www.scbt.com), and Genetex (SGK1: 61249

(13) Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferationScientific ReportsOctober 2, 2017A. M. Masudul Azad Chowdhury, Hiroki Katoh, Atsushi Hatanaka, Hiroko Iwanari, Nanami Nakamura, Takao Hamakubo, Tohru Natsume, Tsuyoshi Waku, Akira Kobayashi

(14) Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathwaysMolecular and cellular biologyApril 1, 2015Wang S, Amato KR, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders DM, Chen J.(T37/46) (catalogue number 2855), total 4E-BP1 (catalogue number 9644), and total NDRG1 (catalogue number 9408) were purchased from Cell Signaling Technology and used according to the manufacturer’s protocols. Cell culture

(15) Rapid elevation of sodium transport through insulin is mediated by AKT in alveolar cellsPhysiological reportsJanuary 1, 2014Mattes C, Laube M, Thome UH.(5482, Cell Signaling Technology, Inc., Danvers, MA) when phosphorylated at Thr346 and NDRG1 antibody (9408, Cell Signaling Technology, Inc.). Phosphorylation of AKT was analyzed using antibodies against phospho‐AKT

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NDRG1 (D6C2) Rabbit mAb

NDRG1 (D6C2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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NDRG1 (D6C2) Rabbit mAb from Cell Signaling Technology

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