The ATP7B Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to ATP7B. This antibody recognizes Homo Sapiens, and Human antigen. The ATP7B Antibody has been shown to work in the following applications: Immunohistochemistry.
Description
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoformswith distinct cellular localizations, have been characterized.Mutations in this gene have been associated with Wilson disease (WD)