The Anti-RPS3 Antibody, Rabbit Polyclonal from AAA Biotech, LLC is a Rabbit Polyclonal antibody to Ribosomal Protein S3, and RPS3. This antibody recognizes Homo Sapiens, and Human antigen. The Anti-RPS3 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Precipitation, Immunoprecipitation, and Western Blot.
Description
Ribosomal protein S3 (rpS3) is a 243 amino acid component of the 40S ribosomal small subunit. It has multiple roles in translation and extra-ribosomal functions like apoptosis and DNA repair. RpS3 is secreted only in cancer cell lines. Ribosomal protein S3 (RpS3) is a well-known multi-functional protein mainly involved in protein biosynthesis as a member of the small ribosomal subunit. It also plays a role in repairing various DNA damage acting like a repair UV endonuclease. Most of the rpS3 pool is located in the ribosome while the minority exists in free form in the cytoplasm. RPS3 has endonuclease activity for DNA repair. In particular, rpS3 cleaves the phosphodiester bonds of damaged DNA. Penetration of the rpS3 repair domain into cells can cleave UV-induced CPDs and reduce MMP-1 expression induced by UV