The ADAM11 Rabbit Polyclonal Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to ADAM11. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ADAM11 Rabbit Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed