The Anti-ADAT3 Antibody, Rabbit Polyclonal from AAA Biotech, LLC is a Rabbit Polyclonal antibody to ADAT3, and adenosine deaminase tRNA specific 3. This antibody recognizes Homo Sapiens, and Human antigen. The Anti-ADAT3 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Adenosine (A)-to-inosine (I) RNA editing is a post-transcriptional RNA process capable of generating RNA and protein diversity. Inosine at wobble position 34 of tRNA anticodons can translate codons ending in uracil, cytosine, or adenine. The modification, which creates an I from an A at position 34 (wobble position) of tRNA, is catalyzed by the heterodimeric enzyme, adenosine deaminase, tRNA-specific 3 (ADAT3)/ADAT2. In humans, a valine-to-methionine mutation (V144M) in ADAT3 that originated ~1, 600 years ago is the most common cause of autosomal recessive intellectual disability (ID) in Arabia