The SRMS Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to SRMS. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The SRMS Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Description: May be involved in proliferation or differentiation of keratinocytes in the skin.
Function: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues (PubMed:23822091). Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues (PubMed:29496907). Phosphorylation of KHDRBS1 is EGF-dependent (PubMed:29496907).
Subunit Structure: Interacts (via the SH2 and SH3 domains) with DOK1 (PubMed:23822091). Interacts with KHDRBS1/SAM68 and VIM (PubMed:29496907).
Similarity: The N-terminal region regulates its kinase activity. Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily