Anti-RUVBL1 Antibody, Rabbit Polyclonal AAA259432 from AAA Biotech, LLC

Description

RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. RUVBL1 is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. It also is essential for cell proliferation. RUVBL1 may be able to bind plasminogen at cell surface and enhance plasminogen activation

Product Specs
ItemAnti-RUVBL1 Antibody, Rabbit Polyclonal
CompanyAAA Biotech, LLC
Price $380.00Supplier Page View Company Product Page
Catalog NumberAAA259432
StorageThis antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below
ReactivityHuman
TypeAntibody
TargetRUVBL1
Quantity0.1 mL, 5x0.1 mL, 4x0.1 mL, 2x0.1 mL, 3x0.1 mL
ClonalityPolyclonal
FormatLiquid; 0.2um filtered solution in PBS
IsotypeRabbit IgG
ApplicationsIHC (Immunohistochemistry)
HostRabbit
Molecular Weight42,127 Da
PurityProtein A & Antigen Affinity
NCBI Full Gene NameRuvB like AAA ATPase 1
NCBI Gene AliasesECP-54, PONTIN, Pontin52, ECP54, TIH1, TIP49A, NMP238, RVB1, NMP 238, INO80H, TIP49
Conjugate/TagUnconjugated