AAA Biotech, LLC's CD3E Rabbit anti-Human Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry. The CD3E Rabbit anti-Human Polyclonal Antibody was generated using CD3E as the antigen and it reacts with Homo Sapiens, and Human.
Description
CD3E antibody is an unconjugated rabbit polyclonal antibody to CD3E from human. Validated for IHC.
CD3e, epsilon (CD3E) is a polypeptide subunit of the T-cell receptor-CD3 complex, which plays an important role in T-cell development and the adaptive immune response. Along with its associated CD3 subunits, it couples activation of T-cell receptors by antigen-presenting cells to intracellular signal transduction pathways. Mutations in the CD3E gene cause immunodeficiency, and the gene may be linked to susceptibility to type 1 diabetes in women. CD3E is expressed in T cells and is found in the bone marrow and tissues of the immune system such as lymph node, spleen, appendix, and tonsil. CD3E antibodies are used to identify T cells in benign and malignant disorders