The Anti-SLC45A4 Antibody, Rabbit Polyclonal from AAA Biotech, LLC is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The Anti-SLC45A4 Antibody, Rabbit Polyclonal has been shown to work in the following applications: Immunohistochemistry.
Description
The solute carrier 45 family (SLC45) consists of four members, A1-A4, which show only 20-30% identity of amino acid sequences among each other. These members apparently have counterparts in all vertebrates. SLC45A1 was initially identified in the rat brain, particularly predominant in the hindbrain, as a proton-associated sugar transport, induced by hypercapnia. The protein is predicted to have 12TM domains, with intracellular termini. The SLC45A2 gene is thought to encode a transporter protein that mediates melanin synthesis. Mutations in SLC45A2 are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color