AAA Biotech, LLC's Anti-OBFC1 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Immunohistochemistry. The Anti-OBFC1 Antibody, Rabbit Polyclonal was generated using STN1, and STN1 subunit of CST complex as the antigen and it reacts with Homo Sapiens, and Human.
Description
The yeast homolog of OBFC1 is Stn1, which plays a critical role in telomere regulation. OBFC1/AAF44 can localize to telomeres in human cells and bind to telomeric single-stranded DNA in vitro. Overexpression of an OBFC1 mutant resulted in elongated telomeres in human cells, implicating OBFC1/AAF4 in telomere length regulation. OBFC1/AAF44 represents a new player in the telomere interactome for telomere maintenance