The LRBA Rabbit Polyclonal Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to LRBA. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The LRBA Rabbit Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Immunohistochemistry.
Description
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]