The Rabbit anti-ROCK2 Antibody, Affinity Purified from AAA Biotech, LLC is a Rabbit Polyclonal antibody to ROCK2. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit anti-ROCK2 Antibody, Affinity Purified has been shown to work in the following applications: Precipitation, Immunoprecipitation, and Western Blot.
Description
Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin