AAA Biotech, LLC's S100 beta Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot. The S100 beta Rabbit Polyclonal Antibody was generated using S100B as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
The protein encoded by this gene is a member of the S100 betaamily of proteins containing 2 EF-hand calcium-binding motifs. S100 betaroteins are localized in the Cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 betaenes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy