The Rabbit anti-human GTP-binding nuclear protein Ran polyclonal Antibody(RAN) from AAA Biotech, LLC is a Rabbit Polyclonal antibody to Ran. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit anti-human GTP-binding nuclear protein Ran polyclonal Antibody(RAN) has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases