Argonaute 2 Rabbit mAb Antibody from AAA Biotech, LLC

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AAA Biotech, LLC for
Argonaute 2 Rabbit mAb Antibody

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AAA Biotech, LLC's Argonaute 2 Rabbit mAb Antibody is a Rabbit monoclonal antibody. The Argonaute 2 Rabbit mAb Antibody was generated using AGO2 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Precipitation, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.

Description

Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions