AAA Biotech, LLC's Anti-RNF11 Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry. The Anti-RNF11 Antibody, Rabbit Polyclonal was generated using RNF11 as the antigen and it reacts with Homo Sapiens, and Human.
Description
The Really Interesting New Gene (RING) Finger protein 11 (RNF11) is a subunit of the A20 ubiquitin-editing complex that ensures the transient nature of inflammatory responses. Ring finger protein 11 (RNF11) is a RING (really interesting new gene)-H2 E3 ligase that is overexpressed in several human tumor tissues. The RING E3 ligase RNF11 is a novel GGA cargo actively participating in regulating the ubiquitination of the GGA protein family. RING finger protein 11 (RNF11), a negative regulator of NF-kappaB signaling pathway, colocalizes with alpha-synuclein and is sequestered in Lewy bodies in Parkinson's disease (PD)