AAA Biotech, LLC's Anti-LAPTM4A Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry. The Anti-LAPTM4A Antibody, Rabbit Polyclonal was generated using Laptm4a as the antigen and it reacts with Homo Sapiens, Human, and Rat.
Description
LAPTM4A (Lysosomal Protein Transmembrane 4 Alpha) is a Protein Coding gene. This gene encodes a protein that has four predicted transmembrane domains. It belongs to the LAPTM4/LAPTM5 transporter family. Studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. Screening within a mating-based split-ubiquitin-yeast-two-hybrid system (mBSUS) revealed the LAPTM4A as a potential interacting protein. Interaction of LAPTM4A and hOCT2 was confirmed by pulldown assays, FRET microscopy analysis, and immunofluorescence microscopy.LAPTM4A has been identified as an interaction partner of hOCT2. LAPTM4A regulates the function of hOCT2 by influencing its trafficking to/from the cell membrane and processing it via the intracellular sorting machinery