The Anti-RASAL1/RASAL1 Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to RASAL1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Anti-RASAL1/RASAL1 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for RASAL1 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.
Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. And it is mapped to 12q24.13. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described