The Rabbit Polyclonal (IgG) to Human WC1 / ATP7B Antibody from AAA Biotech, LLC is a Rabbit Polyclonal antibody to ATP7B. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Polyclonal (IgG) to Human WC1 / ATP7B Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, and Immunohistochemistry.
Description
ATP7b (ATPase, Cu++ Transporting, Beta Polypeptide), also known as Wilson Disease gene (WND) or mouse toxic milk gene, plays a key role in copper transport. Germ-line mutations in this gene cause so-called Wilson disease, which is characterized by the accumulation of toxic levels of copper in the liver, brain, and kidney resulting in extensive tissue damage and eventual death. ATP7b is expressed in a variety of carcinomas and appears to be associated with chemoresistance to cisplatin