AAA Biotech, LLC's C2CD3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunofluorescence, and Immunohistochemistry. The C2CD3 Antibody was generated using C2CD3 as the antigen and it reacts with Homo Sapiens, and Human.
Description
Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed: 24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed: 23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3