PIP2 (PIP2 2C11) Antibody sc-53412 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPIP2 (PIP2 2C11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53412
Antibody TypePrimary Antibodies
ClonePIP2 2C11
Quantity200 µg/ml
ApplicationsIP, IF
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
IsotypeIgM
TargetPIP2

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The LINC00519/hsa- miR- 22- 3p/MECOM Axis Accelerates Intrahepatic Cholangiocarcinoma Progression through PI3K/AKT SignalingMolecular Cancer ResearchNovember 3, 2025Zhuxin Gu, Yanjun Sun, Fajing Chen, Weiwei Gu, Xiaohua Lu, Suming Zhao, Qinan Geng, Yang Yang1:1,000), GAPDH (ab8245, 1:500), and secondary antibodies (ab205719, 1:2,000) were supplied by Abcam. PIP2 (sc-53412, 1:1,000) was from Santa Cruz Biotechnology, and AKT (#9272, 1:1,000) and phosphorylated AKT (p-AKT;

(2) The potassium channel K2P2.1 shapes the morphology and function of brain endothelial cells via actin network remodelingNat CommunJuly 18, 2025Stefanie Lichtenberg, Laura Vinnenberg, Falk Steffen, Isabelle Plegge, Nicholas Hanuscheck, Vera Dobelmann, Joel Gruchot, Christina B. Schroeter, Haribaskar Ramachandran, Beatrice Wasser, et al.or rabbit anit-K2P2.1 (Sigma-Aldrich # T6448, 1:100) and mouse anti-PIP2 (Santa Cruz Biotechnology # sc-53412, 1:80) was performed in buffer (pH 6.8), containing 20 mM PIPES, 137 mM NaCl, 2.7 mM KCl, 0.1 % saponin

(3) Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathwayDiscov OncolMay 16, 2025Juexiao Deng, Yang Li, Lanyue Zhang, Wenxin Liao, Tingting Liu, Fujin Shenthe membrane was incubated overnight at 4 °C with primary antibodies: PIP2 (Santa Cruz, USA, Cat. No. sc-53412) and GAPDH (Proteintech, China, Cat. No. 10494-1-AP). The following day, HRP-conjugated secondary antibodies

(4) miRNAs from Zebrafish Embryo Extracts Inhibit Breast Cancer Invasiveness and Migration by Modulating miR-218-5p/PI3K PathwayInt J Mol SciApril 17, 2025Noemi Monti, Daniele Antinori, Sara Proietti, Aurora Piombarolo, Alessandro Querqui, Guglielmo Lentini, Domenico Liguoro, Michele Aventaggiato, Marco Lucarelli, Andrea Pensotti, et al.BSA, followed by overnight incubation at 4 °C with anti-PIP2 antibody at a 1:100 dilution in BSA 1% (sc-53412 Santa Cruz, Dallas, TX, USA). Cells were then washed three times with PBS and incubated for 1 h with

(5) Cell Membrane Fatty Acids and PIPs Modulate the Etiology of Pancreatic Cancer by Regulating AKTNutrientsDecember 31, 2024Carolina Torres, Georgina Mancinelli, Jee-Wei Emily Chen, Jose Cordoba-Chacon, Danielle Pins, Sara Saeed, Ronald McKinney, Karla Castellanos, Giulia Orsi, Megha Singhal, et al.Primary antibodies PIP3 and PIP2 were purchased from Echelon Biosciences Inc. (Z-P345) and Santa Cruz (sc-53412), respectively, and diluted to 1:100, then 200 µL/well were added to the chamber slides and incubated

(6) Insulin acts as an atypical KCNQ1/KCNE1-current activator and reverses long QT in insulin-resistant aged rats by accelerating the ventricular action potential repolarization through affecting the β(3) -adrenergic receptor signaling pathwayJournal of cellular physiologyFebruary 1, 2022Olgar Y, Durak A, Bitirim CV, Tuncay E, Turan B.

(7) Hederasaponin C Alleviates Lipopolysaccharide-Induced Acute Lung Injury In Vivo and In Vitro Through the PIP2/NF-κB/NLRP3 Signaling PathwayFrontiers in immunologyJanuary 1, 2022Han S, Yuan R, Cui Y, He J, Wang QQ, Zhuo Y, Yang S, Gao H.

(8) T-lymphoma invasion and metastasis 1 promotes invadopodia formation and is regulated by the PI3K/Akt signaling pathway in hepatocellular carcinomaExperimental cell researchOctober 15, 2021Wang B, Zheng B, Cao L, Liao K, Huang D, Zhang Y, Jiang Y, Zheng S.

(9) Paeoniflorin Improved Constipation in the Loperamide-Induced Rat Model via TGR5/TRPA1 Signaling-Mediated 5-Hydroxytryptamine SecretionEvidence-based complementary and alternative medicine : eCAMJanuary 1, 2021Zhan Y, Wen Y, Zhang LL, Shen XL, Chen XH, Wu XH, Tang XG.phospholipase C (PLC)-γ1 (Abcam, ab76155; 1/5000), phosphatidylinositol 4,5-bisphosphate (PIP2; Santa Cruz, sc-53412; 1/200), Tph-1 (Abcam, ab228588; 1/1000), and β-actin (Boster, BM0627; 1/1000). Then, the membrane washing

(10) Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responsesBio SystemsJanuary 1, 2021Miyagi H, Hiroshima M, Sako Y.

(11) IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent wayJournal of experimental & clinical cancer research : CRSeptember 16, 2020Zhang X, Wang D, Liu B, Jin X, Wang X, Pan J, Tu W, Shao Y.

(12) MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca(2+) channels and PIP(2)Vascular pharmacologySeptember 1, 2020Jahan KS, Shi J, Greenberg HZE, Khavandi S, Baudel MM, Barrese V, Greenwood IA, Albert AP.(w/v) milk powder in 0.05% (v/v) PBST. Membranes were then incubated with an anti-PIP2 antibody (1:200; SC-53412, Santa Cruz, USA) overnight at 4 °C. Visualisation was performed with a donkey anti-mouse (1:10,000;

(13) Obligatory role for PKCδ in PIP(2) -mediated activation of store-operated TRPC1 channels in vascular smooth muscle cellsThe Journal of physiologySeptember 1, 2020Martín-Aragón Baudel MAS, Shi J, Large WA, Albert AP.

(14) BIG1 controls macrophage pro-inflammatory responses through ARF3-mediated PI(4,5)P2 synthesisCell death & diseaseMay 15, 2020Liu L, Zhang S, Wang Y, Bao W, Zhou Y, Dang W, Wang X, Li H, Cao X, You Y, et al.Cell Signaling), rabbit polyclonal anti-TIRAP (ab17218, 1:1000, Abcam), mouse monoclonal anti-PIP2 (sc53412, 1:200, Santa Cruz), rabbit polyclonal anti-ARF1 (PA1-127, 1:2000, Thermo Fisher), mouse monoclonal

(15) APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of ActomyosinCell reportsMarch 17, 2020Uzureau S, Lecordier L, Uzureau P, Hennig D, Graversen JH, Homblé F, Mfutu PE, Oliveira Arcolino F, Ramos AR, La Rovere RM, et al.RRID:AB_11008074 Mouse anti-PI(4)P,Echelon,Z-P004; RRID:AB_11127796 "Mouse anti-PI(4,5)P2",Santa cruz,sc-53412; RRID:AB_630097 Rabbit anti-PI4KB,Novus Biologicals,NBP180907; RRID:AB_11040866 Rabbit anti-PI4KB,Merck-Millipore,06-578;

(16) OSBP-Related Protein 5L Maintains Intracellular IP₃/Ca²⁺ Signaling and Proliferation in T Cells by Facilitating PIP₂ HydrolysisJournal of immunology (Baltimore, Md. : 1950)March 1, 2020Xu M, Zhu B, Cao X, Li S, Li D, Zhou H, Olkkonen VM, Zhong W, Xu J, Yan D.was spotted onto nitrocellulose membrane (Bio-Rad Laboratories), probed with PIP2 Ab (2C11) (1:50, sc-53412; Santa Cruz Biotechnology) or PM internal loading control pan-cadherin Ab (C-19) (1:500, sc-1499; Santa Cruz Biotechnology

(17) Hypoxia induces actin cytoskeleton remodeling by regulating the binding of CAPZA1 to F-actin via PIP2 to drive EMT in hepatocellular carcinomaCancer lettersApril 28, 2019Huang D, Cao L, Xiao L, Song JX, Zhang YJ, Zheng P, Zheng SG.

(18) Lipid phosphatases SKIP and SHIP2 regulate fibronectin-dependent cell migration in glioblastomaThe FEBS journalMarch 1, 2019Ramos AR, Ghosh S, Dedobbeleer M, Robe PA, Rogister B, Erneux C.

(19) Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesisOncotargetSeptember 25, 2018Marx B, Hufbauer M, Zigrino P, Majewski S, Markiefka B, Sachsenheimer T, Brügger B, Akgül B.

(20) Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cellsJournal of cell scienceAugust 16, 2018Ghosh S, Scozzaro S, Ramos AR, Delcambre S, Chevalier C, Krejci P, Erneux C.Santa Cruz Biotechnology (Dallas, TX) and was used at 1:500. Antibodies to PI(4,5)P2 (2C11) (catalog number sc-53412, used at 1:200) and to PI(3,4)P2 (catalog number 117ZP034b, used at 1:150) were from Santa Cruz Biotechnology

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PIP2 (PIP2 2C11) Antibody

PIP2 (PIP2 2C11) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PIP2 (PIP2 2C11) Antibody from Santa Cruz Biotechnology, Inc.

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