B7-2 (GL1) Antibody from Santa Cruz Biotechnology, Inc.

Yes, the B7-2 (GL1) Antibody has been utilized in immunofluorescence studies to evaluate macrophage infiltration in human cardiac tissues, specifically in the context of hypertrophic and fibrotic changes associated with polycystic kidney disease. It was used alongside other antibodies to detect macrophage M1 markers, indicating its relevance in such studies (amirrad2023).

The B7-2 (GL1) Antibody is reactive with mouse, rat, and human species. This makes it suitable for studies involving human tissues, as demonstrated in research examining cardiac hypertrophy and fibrosis in human subjects with polycystic kidney disease (amirrad2023).

While the specific performance in Western blotting is not detailed in the provided information, the B7-2 (GL1) Antibody is listed among its applications, suggesting it has been shown to work in this context. Researchers should refer to relevant literature for specific protocols and results.

The B7-2 (GL1) Antibody is of the IgG2a isotype. This isotype can influence the antibody's binding characteristics and its performance in various assays, including immunoprecipitation and immunofluorescence, where isotype compatibility with the secondary antibodies used is crucial for optimal results.