SMN (2B1) Antibody sc-32313 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSMN (2B1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-32313
Antibody TypePrimary Antibodies
NCBI Gene AliasesSMA3, SMA2, SMA1, Gemin1, SMNT, SMA4, GEMIN1, SMN, BCD541, Smn, SMA@, T-BCD541, TDRD16A, SMA
Clone2B1
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human
ClonalityMonoclonal
Conjugate/TagUnconjugated
FormatPurified
Hostmouse
NCBI Full Gene Namesurvival motor neuron 1, survival of motor neuron 1, telomeric
IsotypeIgG1
TargetSMN

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) RNA-Binding Proteins TDP-43 and FUS Promote R-Loop Resolution and Regulate Transcription TerminationJournal of Biological ChemistryMarch 6, 2026Dorothy Yanling Zhao, Syed Nabeel-Shah, Zuyao Ni, Shuye Pu, Guoqing Zhong, Frank W. Schmitges, Ulrich Braunschweig, Benjamin J. Blencowe, Jack F. Greenblatt(Sigma, mAb H9658); PRMT5 (Upstate, pAb C7-405, Santa Cruz, mAb sc-22132); SMN (Santa Cruz Biotechnology, sc-32313; pAb H-195); SETX for ChIP and IP (Novus Biologicals, pAb NB100–57543) and for western blots (Bethyl

(2) Nutrient control of splice site selection contributes to methionine addiction of cancerMolecular MetabolismMarch 1, 2025Da-Wei Lin, Francisco G. Carranza, Stacey Borrego, Linda Lauinger, Lucas D Dantas de Paula, Harika R. Pulipelli, Anna Andronicos, Klemens J. Hertel, Peter Kaiserof lysate was used per IP and filled up to 500 μl with NET buffer. 2 μg of SMN antibody (Santa Cruz, sc-32313) was added and incubated overnight at 4 °C on a nutator. The next day samples were added to 20 μl of

(3) Light-induced targeting enables proteomics on endogenous condensatesCellDecember 12, 2024Choongman Lee, Andrea Quintana, Ida Suppanz, Alejandro Gomez-Auli, Gerhard Mittler, Ibrahim I. Cisséovernight at 4°C in 2% BSA buffer; PSPC1 (Rabbit, Invitrogen, PA5–58585, 1:100), SMN1 (Mouse, Santa Cruz, sc-32313, 1:200), FBL (Mouse, Abcam, ab4566, 1:500), and SC35 (Mouse, Abcam, ab11826, 1:200). Then, cells were

(4) Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophyJournal of Clinical InvestigationJune 17, 2024Damien Meng-Kiat Leow, Yang Kai Ng, Loo Chien Wang, Hiromi W.L. Koh, Tianyun Zhao, Zi Jian Khong, Tommaso Tabaglio, Gunaseelan Narayanan, Richard M. Giadone, Radoslaw M. Sobota, et al.production was quantified using MitoSOX (Invitrogen). Fixed cells were used to assess intracellular SMN (sc-32313, Santa Cruz Biotechnology), SDHB (sc-271548, Santa Cruz Biotechnology), MT-CO1 (ab154477, Abcam), and

(5) Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophyJ Clin InvestMay 9, 2024Damien Meng-Kiat Leow, Yang Kai Ng, Loo Chien Wang, Hiromi W.L. Koh, Tianyun Zhao, Zi Jian Khong, Tommaso Tabaglio, Gunaseelan Narayanan, Richard M. Giadone, Radoslaw M. Sobota, et al.production was quantified using MitoSOX (Invitrogen). Fixed cells were used to assess intracellular SMN (sc-32313, Santa Cruz Biotechnology), SDHB (sc-271548, Santa Cruz Biotechnology), MT-CO1 (ab154477, Abcam), and

(6) Moxifloxacin rescues SMA phenotypes in patient-derived cells and animal modelCellular and molecular life sciences : CMLSJuly 22, 2022Januel C, Menduti G, Mamchaoui K, Martinat C, Artero R, Konieczny P, Boido M.(MF20),MF20,Mouse,DSHB,1:200 Motoneurons,Primary,Acetylocholine receptor (AchR),mAB 35,Rat,DSHB,1:350 Motoneurons,Primary,SMN,Sc-32313,Mouse,Santa Cruz Biotechnology,1:200 Motoneurons,Secondary,Donkey anti-mouse IgG (H + L) alexa fluor 488

(7) Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptidesThe EMBO journalJuly 1, 2021Lafarga V, Sirozh O, Díaz-López I, Galarreta A, Hisaoka M, Zarzuela E, Boskovic J, Jovanovic B, Fernandez-Leiro R, Muñoz J, et al.

(8) RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cellsGenes to cells : devoted to molecular & cellular mechanismsMay 1, 2021Imada T, Shimi T, Kaiho A, Saeki Y, Kimura H.

(9) DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAsNucleic acids researchJune 19, 2020Roithová A, Feketová Z, Vaňáčová Š, Staněk D.

(10) Role for the splicing factor TCERG1 in Cajal body integrity and snRNP assemblyJournal of cell scienceNovember 14, 2019Moreno-Castro C, Prieto-Sánchez S, Sánchez-Hernández N, Hernández-Munain C, Suñé C.Santa Cruz Biotechnology) at 1:2000; anti-Sm (Y12) (MS-450; Thermo Fisher Scientific, Waltham, MA) at 1:1000; anti-SMN (sc-32313; Santa Cruz Biotechnology) at 1:500; antiglyceraldehyde-3-phosphate dehydrogenase (GAPDH) (sc-365062;

(11) XIAP controls RIPK2 signaling by preventing its deposition in speck-like structuresLife science allianceAugust 1, 2019Ellwanger K, Briese S, Arnold C, Kienes I, Heim V, Nachbur U, Kufer TA.anti–cleaved-caspase-3 (Asp175, #9661S; Cell Signaling Technology), anti-XIAP (M044-3; MBL), anti-SMN (sc-32313; Santa Cruz), anti-Gemin3 (sc-57007; Santa Cruz), anti-EEA1 (sc-53939; Santa Cruz), anti-LC3β (3868;

(12) Liquid Nuclear Condensates Mechanically Sense and Restructure the GenomeCellNovember 29, 2018Shin Y, Chang YC, Lee DSW, Berry J, Sanders DW, Ronceray P, Wingreen NS, Haataja M, Brangwynne CP.Santa Cruz sc32860, 1 to 100), TDP43 (Rabbit, ProteinTech 10782-2-AP, 1 to 100), SMN1 (Mouse, Santa Cruz sc-32313, 1 to 100), SC35 (Mouse, AbCam ab11826, 1 to 1000), and FBL (Mouse, AbCam ab4566, 1 to 40). Cells were

(13) CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear OrganizationCellNovember 15, 2018Wang H, Xu X, Nguyen CM, Liu Y, Gao Y, Lin X, Daley T, Kipniss NH, La Russa M, Qi LS.fixed cells. Immunohistochemistry was performed by using mouse monoclonal anti-SMN (Santa Cruz, Cat.# sc-32313), anti-Fibrillarin (Abcam, Cat.# ab4566), anti-Gemin2 antibody (Santa Cruz, Cat.# sc-32806), and a donkey

(14) Application of urine cells in drug intervention for spinal muscular atrophyExperimental and therapeutic medicineSeptember 1, 2017Zhang QJ, Lin X, Li JJ, Lu YQ, Guo XX, Dong EL, Zhao M, He J, Wang N, Chen WJ.temperature for 1 h). Cells were then probed using a SMN1 mouse monoclonal antibody (1:50; catalogue no. sc-32313; Santa Cruz Biotechnology, Inc., Dallas, TX USA) at 4°C overnight. Alexa Fluor 594 conjugated affinipure

(15) RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent intronsNucleic acids researchJanuary 9, 2017Doktor TK, Hua Y, Andersen HS, Brøner S, Liu YH, Wieckowska A, Dembic M, Bruun GH, Krainer AR, Andresen BS.knockdowns were used in RNA-sequencing. Knockdown was confirmed by Western blotting using anti-SMN (SC-32313, Santa Cruz Biotechnology) and anti-SRSF3 (SC-13510, Santa Cruz Biotechnology) as a loading control. RNA-seq

(16) Hypermethylated-capped selenoprotein mRNAs in mammalsNucleic acids researchJuly 1, 2014Wurth L, Gribling-Burrer AS, Verheggen C, Leichter M, Takeuchi A, Baudrey S, Martin F, Krol A, Bertrand E, Allmang C.

(17) Survival of motor neuron protein downregulates miR-9 expression in patients with spinal muscular atrophyThe Kaohsiung journal of medical sciencesMay 1, 2014Wang LT, Chiou SS, Liao YM, Jong YJ, Hsu SH.

(18) Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factorsExperimental cell researchMarch 10, 2014Hu Y, Ericsson I, Doseth B, Liabakk NB, Krokan HE, Kavli B.

(19) Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritisJournal of cellular and molecular medicineJanuary 1, 2014Cucchiarini M, Madry H, Terwilliger EF.

(20) Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturationMolecular cellMarch 9, 2012Xiao R, Tang P, Yang B, Huang J, Zhou Y, Shao C, Li H, Sun H, Zhang Y, Fu XD.

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SMN (2B1) Antibody

SMN (2B1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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SMN (2B1) Antibody from Santa Cruz Biotechnology, Inc.

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