The TLR3 Polyclonal Antibody, Cy5.5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to TLR3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The TLR3 Polyclonal Antibody, Cy5.5 Conjugated has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity)