TIMP-1 (2A5) Antibody sc-21734 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTIMP-1 (2A5) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-21734
NCBI Gene AliasesTIMP, TPA-S1, TIMP-1, Timp, EPO, CLGI, Clgi, HCI, EPA
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Clone2A5
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human
ClonalityMonoclonal
Hostmouse
FormatPurified
Conjugate/TagUnconjugated
NCBI Full Gene Nametissue inhibitor of metalloproteinase 1, TIMP metallopeptidase inhibitor 1
TargetTIMP-1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The TRAF6/SPP1 axis participates in osteoarthritis progression through regulating the catabolism and anabolism of cartilage matrixScientific ReportsMarch 4, 2026Jiapei Yao, Jiliu Huang, Chongrui Li, JingJing Shang, Xiaolong Lin, Xindie Zhou, Yaojun LuAbcam, UK) antibodies acquired from Proteintech. The tissue inhibitor of metalloproteinase 1 (TIMP1) (sc-21734, Santa Cruz, California, USA) antibody was procured from Santa Cruz Biotechnology. Fibronectin fragment

(2) Dose-dependent effects of atorvastatin on inflammatory response in endothelial cells: MMP/TIMP balance and in vitro wound closure assayBMC Molecular and Cell BiologyFebruary 16, 2026Betül İşiner, Aslı Fahriye Ceylan, Büşra Görgün, Leyla Didem KozacıPBS-T, 1:1000, cat. no. Clone F27P3A4) and Santa Cruz Biotechnology (dilution, PBS-T, 1:1000, cat. no. sc-21734), respectively. The source of the anti-human beta-actin antibody was Elabscience (dilution, PBS-T, 1:3000,

(3) Kaempferia parviflora Extract Stabilizes Cartilage Homeostasis via TIMP-1–Associated Matrix Modulation in Monosodium Iodoacetate–Induced Rat OsteoarthritisPharmaceuticals (Basel)January 25, 2026DongHoon Lee, Jong Seong Ha, Anna Jo, HyeMin Seol, JiSoo Han, Seong-Un Jeong, Seol-Ji Baek, Wan-Su ChoiCell Signaling Technology, Danvers, MA, USA), anti-MMP13 (ab39012; Abcam, Cambridge, UK), anti-TIMP-1 (sc-21734; Santa Cruz Biotechnology, Dallas, TX, USA), and anti-β-actin (sc-47778; Santa Cruz Biotechnology, Dallas,

(4) Co-treatment of trigonelline and everolimus synergistically prevented chronic steatohepatitis induced by fast food diet and thioacetamide in a novel murine nonalcoholic steatohepatitis modelIndian Journal of PharmacologyJuly 21, 2025Raghu Rai Sharma, Love Sharma, Haroon Rashid, Aalim Maqsood Bhat, Divya Gupta, Sheikh Abdullah Tasduqanti-tumor necrosis factor-alpha (TNF-α) (sc-1350), anti-tissue inhibitors of metalloproteinases-1 (TIMP-1) (sc-21734), anti-SREBP-1 (sc-366), anti-PPAR-Ƴ (sc-7196), anti-CD-36 (sc-9154), Santa-Cruz Biotechnology, USA,

(5) GPR56 function as a key repressor in hepatocyte pyroptosis and the pathogenesis of liver fibrosisJ Transl MedJune 6, 2025Zhemin Shi, Qi Liu, Mengxia Zhang, Xiaoxiao Du, Yifan He, Lina Zheng, Wei Hong, Tao Han, Kun ZhangECL luminescent solution. Primary antibodies included TIMP1 (1:1000, mouse monoclonal, Santa Cruz, sc-21734), MMP2 (1:2000, rabbit monoclonal, Abcam, ab92536), α-SMA (1:1000, rabbit polyclonal, Abcam, ab5694),

(6) Polygonum multiflorum Inhibits Pulmonary Inflammation and Fibrosis in PM2.5-Induced Dysfunction Through the Regulation of the TLR4/TGF-β1 Signaling Pathway in MiceInternational Journal of Molecular SciencesMay 25, 2025Hye Ji Choi, Hyo Lim Lee, In Young Kim, Ho Jin HeoUSA)" BAX,sc-7480, Caspase-9,sc-56076, Caspase-3,sc-56053, TGF-β1,sc-130348, p-Smad-3,sc-517575, MMP-9,sc-13520, TIMP-1,sc-21734, Keap1,sc-514914, HO-1,sc-136960, COX-2,ab15191,"Abcam (Cambridge, UK)" "Abcam (Cambridge, UK)",Collagen

(7) BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammationAutophagyApril 22, 2025Sangseob Kim, Cheoljun Choi, Yeonho Son, Junhyuck Lee, Sungug Joo, Yun-Hee Lee,Cell Signaling Technology,2148S COL1A1,Mouse,Santa Cruz Biotechnology,sc -293182 TIMP1,Mouse,Santa Cruz Biotechnology,sc -21734 ACTB,Mouse,Santa Cruz Biotechnology,sc -47778 TUBB,Rabbit,Cell Signaling Technology,2148S Antibodies

(8) Myosin Light Chain 9 Mediates Graft Fibrosis After Pediatric Liver Transplantation Through TLR4/MYD88/NF-κB SignalingCellular and molecular gastroenterology and hepatologyJanuary 1, 2025Zhang Z, Dong C, Zhao S, Si Z, Zheng W, Wang K, Sun C, Song Z, Gao W.name,Brand,ID MYL9,Abcam,ab191393 COL1A1,Abcam,ab270993/ab138492 MMP-2,Abcam,ab92536 MMP-9,Abcam,ab76003 TIMP-1,Santa Cruz,sc21734 Desmin,Abcam,ab32362 TGF-β1,Abcam,ab215715 α-SMA,Abcam,ab124964 TLR4,Santa Cruz,sc-293072 MYD88,Abcam,ab219413 p-P65,Abcam,ab76302 P65,Abcam,ab32536 p-IκBα,Cell Signaling Technology

(9) Establishment of a nomogram model based on immune-related genes using machine learning for aortic dissection diagnosis and immunomodulation assessmentInternational journal of medical sciencesJanuary 1, 2025Hou Y, Zhao Y, Shi Z, Pan Y, Shi K, Zhao C, Liu S, Chen Y, Zhao L, Wu J, et al.PTX3 (Invitrogen, #PA5-101097, 1:1000), ITGA5 (Protein tech, #10569-1-AP, 1:1000), TIMP1 (Santa Cruz, #sc-21734, 1:1000), and β-actin (Santa Cruz, #sc-47778, 1:2000) primary antibodies were used in this study. After

(10) TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo studyMolecular MedicineNovember 23, 2024Bo Peng, Zhiwei Feng, Ao Yang, Jinmin Liu, Jinwen He, Lihu Xu, Cong Tian, Xiaoyun Sheng, Yaobin Wang, Rongjin Chen, et al.pre-cleared at 4 °C for 1 h. The supernatant was then incubated with a TIMP1 antibody (SANTA CRUZ, sc21734) on a rotating device at room temperature for 15 min, followed by overnight incubation with Protein A/G PLUS-Agarose

(11) Involvement of oxidative stress-AMPK-Cx43-NLRP3 pathway in extracellular matrix remodeling of gastric smooth muscle cells in rats with diabetic gastroparesisCell stress & chaperonesJune 1, 2024Song B, Zhang G, Bao Y, Zhang M.antibody (ab92536, Abcam, Cambridge, UK); TGF-β3 antibody (A8460, ABclonal, MA, USA); TIMP-1 antibody (SC-21734, Santa Cruz Biotechnology, TX, USA); phospho (p)-AMPK antibody (Cat No. ab133448, Abcam, Cambridge,

(12) The Effects of Chronic Immunosuppressive Treatment on Morphological Changes in Cardiac Tissue and the Balance between Matrix Metalloproteinases (MMP-2 and MMP-9) and Their Inhibitors in the Rat HeartInternational Journal of Molecular SciencesApril 18, 2024Anna Surówka, Michał Żołnierczuk, Piotr Prowans, Marta Grabowska, Patrycja Kupnicka, Marta Markowska, Joanna Olejnik-Wojciechowska, Zbigniew Szlosser, Aleksandra Wilk, Kamila Szumilas, et al.blocking buffer (5% BSA) for 60 min. Protein expression was detected using antibodies against TIMP-1 (sc21734) and TIMP-2 (sc71735) (Santa Cruz Biotechnology, Dallas, TX, USA) diluted 1:100, and sAb goat anti-mouse IgG HRP

(13) Immunolocalization of Matrix Metalloproteinases 2 and 9 and Their Inhibitors in the Hearts of Rats Treated with Immunosuppressive Drugs—An Artificial Intelligence-Based Digital AnalysisBiomedicinesMarch 30, 2024Aleksandra Wilk, Małgorzata Król, Kajetan Kiełbowski, Estera Bakinowska, Kamila Szumilas, Anna Surówka, Karolina Kędzierska-Kapuzaat 1:250 (sc-13520; Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA) and anti-TIMP-1 at 1:250 (sc-21734; Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA) and mouse anti-TIMP-2 at 1:250 (sc-21735; Santa Cruz Biotechnology, Inc

(14) SKIL/SnoN attenuates TGF-β1/SMAD signaling-dependent collagen synthesis in hepatic fibrosisBiomolecules and BiomedicineDecember 1, 2023Cheng Chi, Xifeng Liang, Tianyu Cui, Xiao Gao, Ruixia Liu, Chenghong Yin(dilution 1:100; Abcam), FN (dilution 1:500; Santa Cruz; sc-8422), TIMP-1 (dilution 1:200; Santa Cruz; sc-21734), and MMP-13 (dilution 1:100; Santa Cruz; sc-515284) overnight at 4 ∘C. Beta actin (β-actin) was used

(15) Effect of the Combination of Probiotics and Korean Red Ginseng on Diabetic Wound Healing Exposed to Diesel Exhaust Particles(DEPs)Medicina (Kaunas, Lithuania)June 15, 2023An HM, Choi YS, Bae SK, Lee YK.USA), anti-MMP-9 polyclonal antibody (ab76003, 1:500 dilution, Abcam), anti-TIMP-1 monoclonal antibody (SC-21734; 1:1000 dilution; Santa Cruz Biotechnology), or anti-β-actin polyclonal antibody (4970S; 1:5000 dilution;

(16) Single-Dose Treatment with Rapamycin Preserves Post-Ischemic Cardiac Function through Attenuation of Fibrosis and Inflammation in Diabetic RabbitInternational journal of molecular sciencesMay 19, 2023Samidurai A, Saravanan M, Ockaili R, Kraskauskas D, Lau SYV, Kodali V, Ramasamy S, Bhoopathi K, Nair M, Roh SK, et al.mouse monoclonal antibody specific for TGFβ1 (sc-52893), galectin-3 (B2C10; sc-32790), TIMP-1 (2A5; sc-21734), MYH (b-5; sc-376157) and Smad 1/2/3 (H-2; sc-7960), purchased from Santa Cruz Biotechnology, Inc.,

(17) Rotenone induced neurodegeneration is mediated via cytoskeleton degradation and necroptosisBiochimica et biophysica acta. Molecular cell researchMarch 1, 2023Roy T, Chatterjee A, Swarnakar S.

(18) Regulation of SIRT1-TLR2/TLR4 pathway in cell communication from macrophages to hepatic stellate cells contribute to alleviates hepatic fibrosis by LuteolosideActa histochemicaJanuary 1, 2023Xiu M, Zhao Y, Wang X, Yuan S, Qin B, Sun J, Cui L, Song J.

(19) GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell ActivationCellular and molecular gastroenterology and hepatologyJanuary 1, 2023Zhang H, Zhou P, Xing W, Chen L, Zhou Y, Yang H, Fu K, Liu Z.kDa α-SMA,Proteintech,14395-1-AP,1:1000 (WB); 43 kDa Col1α1,Proteintech,67288-1-Ig,1:5000 (WB); 120–130 kDa TIMP1,Santa Cruz,sc-21734,1:200 (WB); 31.5 kDa P75NTR,Proteintech,55014-1-AP,1:500 (WB); 70 kDa GFAP,Abcam,ab7260,1:5000 (WB);

(20) pH-Responsive Delivery of H2 through Ammonia Borane-Loaded Hollow Polydopamine for Intervertebral Disc Degeneration TherapyOxidative medicine and cellular longevityJanuary 1, 2023Wang W, Xiao B, Qiu Y, Liu Y, Tang G, Deng G, Xi Y, Xu G, Wang Y.aggrecan (1 : 2000; DF7561, Affinity), MMP-13 (1 : 3000; 18165-1-AP, ProteinTech), and TIMP-1 (1 : 1000; sc-21734, Santa Cruz). Next, the HRP-conjugated antibody (1 : 10000; ab6747, Abcam) was used as the secondary

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TIMP-1 (2A5) Antibody

TIMP-1 (2A5) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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TIMP-1 (2A5) Antibody from Santa Cruz Biotechnology, Inc.

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