Syk (4D10) Antibody sc-1240 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSyk (4D10) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-1240
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM
Reactivitymouse, rat, human
FormatPurified
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
Clone4D10
Hostmouse
TargetSyk
IsotypeIgG2a
NCBI Gene AliasesIMD82, p72-Syk, Sykb
ClonalityMonoclonal
NCBI Full Gene Namespleen tyrosine kinase, spleen associated tyrosine kinase

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Visomitin as a differentiation-inducing therapeutic agent through SYK inhibition in AMLFrontiers in PharmacologyFebruary 24, 2026Byeol-Eun Jeon, Chan-Seong Kwon, Ji-Eun Lee, Su-Ji Lee, Youngseuk Cho, Ho-Jin Shin, Sang-Woo Kim, Youngmi Jung(Cell Signaling Technology; 5883S), P-Histone H2A.X (Cell Signaling Technology; 9718S), SYK (Santa Cruz Biotechnology; sc-1240), phospho-SYK (Cell Signaling Technology; 2710S), and β-actin (Santa Cruz Biotechnology; sc-4778). HRP-conjugated

(2) Characterization of Novel Variants in P2YRY12, GP6 and TBXAS1 in Patients with Lifelong History of BleedingBiomoleculesNovember 21, 2025Ana Zamora-Cánovas, Ana Marín-Quílez, Lorena Díaz-Ajenjo, Ana Sánchez-Fuentes, Pedro Luis Gómez-González, Marilena Crescente, Nuria Fernández-Mosteirín, José Padilla, José Ramón González-Porras, Rocío Benito, et al.(Cell Signaling Technology, Rabbit #3584, 1:200), anti-Syk (4D10) (Santa Cruz Biotechnology, Mouse, sc-1240, 1:200), anti-LAT(B-3) (Santa Cruz Biotechnology, Mouse, sc-373706, mouse, 1:1000) followed by secondary

(3) EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1PLoS PathogJune 9, 2025Ru Gao, Heping Wang, Zhihui Cui, Yanyun Du, Ruirui He, Lingyun Feng, Bo Zeng, Yangyang Li, Guoling Huang, Ting Pan, et al.anti-ERK1/2, and anti-actin were purchased from Santa Cruz Biotechnology (cat. no. sc-13119, sc-2710S, sc-1240, sc-7383, sc-514302, and sc-58673, respectively). Flow cytometry antibodies, including anti-CD3 (clone

(4) MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axisCell Death DisJune 4, 2025Yukai Jing, Yunfei Zhang, Xiaocui Wang, Yufen Wang, Ying Hu, Bin Wen, Xin Dai, Xuemei Duan, Haonan Li, Shumin Dong, et al.used: anti-Phosphotyrosine (ab10321, Abcam), anti-pSyk (2710S, Cell Signaling Technology), anti-Syk (sc-1240, Santa Cruz), anti-pBLNK (62144S, Cell Signaling Technology), anti-BLNK (sc-8003, Santa Cruz), anti-pFoxO1

(5) Inflammatory signaling pathways play a role in SYK inhibitor resistant AMLSci RepApril 5, 2025Sarah Tausch, Christina Villinger, Gabriela Alexe, Daniel J. Urban, Min Shen, Dominique Jahn, Jonas Vischedyk, Sebastian Scheich, Hubert Serve, Matthew D. Hall, et al.sc-28342), phospho- SYK Y525/Y526 (Cell Signaling Technology, No. 2711), SYK (Santa Cruz Biotechnology, No. sc-1240),GAPDH (D16H11) XP (Cell Signaling Technology, Cat. No. 5174), α-Tubulin (11H10) (Cell Signaling Technology,

(6) Single cell transcriptomics reveals early photoreceptor states, cell-specific transcript isoforms, and cancer-predisposing featuresbioRxivNovember 26, 2024Dominic W.H. Shayler, Kevin Stachelek, Linda Cambier, Sunhye Lee, Jinlun Bai, Mark W. Reid, Daniel J. Weisenberger, Bhavana Bhat, Jennifer G. Aparicio, Yeha Kim, et al.(1:200),Santa Cruz,"CAT# SC-514134, RRID: AB_2737293" Mouse monoclonal anti-SYK (1:200),Santa Cruz,"CAT# SC1240, RRID: AB_628308" Rabbit polyclonal anti-ARR3 (1:5000),"Cheryl Craft (Li et al., 2003; Zhang et al.,

(7) Expression of variant isoforms of the tyrosine kinase SYK differentially regulates cervical cancer progression through PI3K/AKT pathwayScientific ReportsNovember 23, 2024Bingjie Lin, Qixin Wang, Xin Wang, Hongjian Wei, Xiaojing Nie, Li Li, Yonghua Shithe primary antibody overnight at 4 °C. The applied primary antibodies were as follows: anti-SYK (#sc1240, Santa Cruz, USA), anti-PI3Kinase p110α (#4255, Cell Signaling Technology, USA), anti-Phospho-PI3Kinase

(8) Neutrophil-specific interactome of ARHGAP25 reveals novel partners and regulatory insightsScientific reportsAugust 29, 2024Sasvári P, Pettkó-Szandtner A, Wisniewski É, Csépányi-Kömi R.membranes were incubated with primer antibodies in 1:1000 dilution overnight at four °C (Anti-SYK [cat no: sc-1240] from Santa Cruz; anti-ACSL1 [cat no: 4047S], anti-LDHA [cat no: 2012S], and anti-RHOG [cat no: E9B7Z]

(9) AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H(2)O(2) Activation of Syk/PI3K/Akt Signaling AxisJournal of CancerJanuary 1, 2024Wang Q, Lin B, Wei H, Wang X, Nie X, Shi Y.(#AF5222, Affinity, China), Phospho-Syk (Tyr525/526) (#2710s, Cell Signaling Technology, USA), Syk (#sc1240, Santa Cruz, USA), Phospho-PI3Kinase p85α (Y607) (#ab182651, Abcam, UK), PI3Kinase p85α (#AF6241, Affinity,

(10) Role of SHP2 (PTPN11) in glycoprotein VI-dependent thrombus formation: Improved platelet responsiveness by the allosteric drug SHP099 in Noonan syndrome patientsThrombosis researchAugust 1, 2023Fernández DI, Diender M, Hermida-Nogueira L, Huang J, Veiras S, Henskens YMC, Te Loo MWM, Heemskerk JWM, Kuijpers MJE, García Á.

(11) SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancerSignal transduction and targeted therapyMay 15, 2023Zhou J, Zhang XC, Xue S, Dai M, Wang Y, Peng X, Chen J, Wang X, Shen Y, Qin H, et al.

(12) Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBNCellsFebruary 1, 2023Chang HW, Sim KH, Lee YJ.IKK (#sc-7607), LAT (#sc-53550), Lyn (#sc-376100), PLCγ1 (#sc-7290), SHP-1 (#sc-7289), Syk (#sc-929, sc-1240), and p-tyrosine (pY) (#sc-7020) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA); anti-CRBN

(13) Adiponectin receptor agonist AdipoRon modulates human and mouse platelet functionActa pharmacologica SinicaFebruary 1, 2023Zhou XH, Cheng ZP, Lu M, Lin WY, Luo LL, Ming ZY, Hu Y.

(14) Loss of NF1 in Melanoma Confers Sensitivity to SYK Kinase InhibitionCancer researchJanuary 18, 2023Abecunas C, Whitehead CE, Ziemke EK, Baumann DG, Frankowski-McGregor CL, Sebolt-Leopold JS, Fallahi-Sichani M.

(15) Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formationJournal of thrombosis and haemostasis : JTHNovember 1, 2022Jooss NJ, Smith CW, Slater A, Montague SJ, Di Y, O'Shea C, Thomas MR, Henskens YMC, Heemskerk JWM, Watson SP, et al.

(16) Glutamyl-prolyl-tRNA synthetase 1 coordinates early endosomal anti-inflammatory AKT signalingNature communicationsOctober 29, 2022Lee EY, Kim SM, Hwang JH, Jang SY, Park S, Choi S, Lee GS, Hwang J, Moon JH, Fox PL, et al.following antibodies were from Santa Cruz Biotechnology: anti-STK26 (1:1000, sc-376649), anti-SYK (1:1000, sc-1240), anti-OSR1 (1:1000, sc-376545), anti-PKA (1:1000, sc-365615), anti-PKN (1:1000, sc-393344), anti-BTK

(17) Spleen tyrosine kinase regulates keratinocyte inflammasome activation and skin inflammation induced by UVB irradiationFree radical biology & medicineFebruary 20, 2022Lu PH, Wang JY, Chiu LY, Huang YT, Hung CF, Wu NL.

(18) Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 miceJournal of neuroinflammationFebruary 5, 2022Zhang SS, Zhu L, Peng Y, Zhang L, Chao FL, Jiang L, Xiao Q, Liang X, Tang J, Yang H, et al.(Abcam, ab150299, 1:1000), mouse anti-ADAM10 (Santa Cruz, sc-28358, 1:500), mouse anti-SYK (Santa Cruz, sc-1240, 1:300), rabbit anti-phospho-SYK (Tyr525/526) (CST, 2710, 1:300), mouse anti-β-tubulin and mouse anti-β-actin

(19) Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cellsPloS oneJanuary 1, 2022Denis V, Cassagnard N, Del Rio M, Cornillot E, Bec N, Larroque C, Jeanson L, Jarlier M, Combès E, Robert B, et al.overnight at 4°C with gentle shaking. The antibodies used were: mouse monoclonal anti-Syk (1:500) (4D10, #sc1240 Santa Cruz Biotechnology); rabbit polyclonal anti-Phospho-Akt (1:2,000) (#4060, Cell Signaling Technology);

(20) Insulin-regulated aminopeptidase contributes to setting the intensity of FcR-mediated inflammationFrontiers in immunologyJanuary 1, 2022Bratti M, Vibhushan S, Longé C, Koumantou D, Ménasché G, Benhamou M, Varin-Blank N, Blank U, Saveanu L, Ben Mkaddem S.

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Syk (4D10) Antibody

Syk (4D10) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Syk (4D10) Antibody from Santa Cruz Biotechnology, Inc.

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