IL-4 (HIL41) Antibody from Santa Cruz Biotechnology, Inc.

Yes, the IL-4 (HIL41) antibody has been utilized in studies investigating the role of IL-4Rα in neuronal apoptosis and cell viability during cerebral ischemia. For instance, in a study by Lee et al. (2018), the antibody was employed in immunohistochemistry to analyze IL-4Rα expression in brain tissues following ischemic stroke, demonstrating its involvement in neuroprotection during the acute phase of infarction (lee2018).

The IL-4 antibody has been shown to be effective in studies involving human monocytes. In research by Schrijver et al. (2023), the antibody was used in Western blotting to confirm the presence of IL-4 in a fusion protein context, indicating its utility in examining IL-4's effects on immune responses in human cells, particularly in the context of sepsis-induced immunoparalysis (schrijve2023).

The IL-4 antibody has been applied in research focused on allergic responses, particularly in the context of nasal mucosal fibroblasts. Zeng et al. (2024) utilized this antibody to investigate the production of IL-4 by fibroblasts and its role in inducing Th2 cell differentiation, which is crucial for the pathogenesis of allergic rhinitis (zeng2024).

The IL-4 (HIL41) antibody has been cited in various applications, including Western blotting, ELISA, immunofluorescence, and immunoprecipitation. It has been referenced in at least five scientific articles, highlighting its versatility in studying IL-4's role in different biological contexts, such as inflammation and immune responses.