The PRAME Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to PRAME, and PRAME nuclear receptor transcriptional regulator. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The PRAME Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis