p27 Kip1 (F-8) Antibody from Santa Cruz Biotechnology, Inc.

Yes, the p27 Kip1 (F-8) antibody has been utilized in various studies to investigate its role in cancer. For instance, research has shown that the expression of p27 is regulated by Notch1 signaling in colorectal cancer cells, where its levels increase upon Notch1 knockdown, suggesting its involvement in cell cycle regulation and chemotherapy sensitivity (hristova2013).

The p27 Kip1 (F-8) antibody has been successfully used in immunofluorescence assays, as indicated by its application in studies examining the localization and stabilization of p27 in various cell types, including those expressing viral proteins that induce cell cycle arrest (kumar2013).

The p27 Kip1 (F-8) antibody is reactive with multiple species, including human, mouse, and rat, making it versatile for studies involving these organisms (sc1641).

Yes, the p27 Kip1 (F-8) antibody has been cited in studies exploring its role in cell cycle regulation and apoptosis in various cancer models, including its stabilization in neuroblastoma cells treated with Prozac, which enhances its expression and contributes to anti-cancer effects (bibbo2020).