IL-6 (E-4) Antibody sc-28343 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemIL-6 (E-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-28343
Antibody TypePrimary Antibodies
NCBI Gene AliasesCDF, HSF, BSF-2, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
Quantity200 µg/ml
CloneE-4
Reactivityhuman
ApplicationsWB, IP, IF, IHC(P), ELISA
FormatPurified
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
NCBI Full Gene Nameinterleukin 6
TargetIL-6
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) IL-35 enhances IL-10⁺ breg-mediated immunoregulation and attenuates inflammation and fibrosis in systemic sclerosisArthritis Research & TherapyJanuary 30, 2026Wen Zeng, Dongmei Pan, Chunxiu Lu, Jie Pan, Xu Wang, Mu Huang, Hanyou Mo, Leting Zheng, Ling Leiantibody (Columbia, MD, USA; Cat# 32727), a Mouse IL-6 antibody (Santa Cruz Biotechnology, USA; Cat# SC-28343), Mouse monoclonal CD19 antibody (Novus Biologicals, USA; Cat# NBP2-25196SS), Rat Anti-IL-10 antibody

(2) Nivolumab and bevacizumab attenuate cisplatin-induced hepatic inflammation and apoptosis in ratsHepatology ForumJanuary 15, 2026Ogur Karhan, Sibel Turediminutes. Primary antibodies—TNF-α (Santa Cruz Biotechnology, Inc., Cat. No. sc-52746), IL-6 (Cat. No. sc-28343), VEGF (Cat. No. sc-7269), Bax (Cat. No. sc-7480), Bcl-2 (Cat. No. sc-7382), and Caspase-3 (Cat. No.

(3) IFI16/IFI202 blockade suppresses tumor growth through CD8+ T-cell–mediated immunityBreast Cancer ResearchJanuary 3, 2026Ga Young Lim, Na-Lee Ka, Seung-Su Kim, Mi-Ock LeeCell Signaling Technology), NF-κB p65 (8242, Cell Signaling Technology), IL-1β (MAB201, R&D Systems), IL-6 (sc-28343, Santa Cruz Biotechnology), granzyme B (ab4059, Abcam), interferon-gamma (IFN-γ) (MAB485, R&D Systems),

(4) The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted FactorAging CellDecember 5, 2025Gabriela Makulyte, Hasan Safwan-Zaiter, Delphine Goehrig, Anda Huna, Adèle Mangelinck, Takumi Mikawa, Alberta Palazzo, Lyvia Moudombi, Jean-Jacques Medard, Marie Chanal, et al.4°C with primary antibodies in TBS‐T with 5% milk: α‐ANGPTL4 (sc‐373761, Santa Cruz, 1/250), α‐IL6 (sc‐28343, Santa Cruz, 1/500), α‐FURIN (18413‐1‐AP, Proteintech, 1/1000), α‐TUBULIN (T6199‐100, Sigma, 1/5000).

(5) Human fibroblasts from aged individuals exhibit chromosomal instability through replication stress caused by oxidative stressnpj AgingNovember 25, 2025Kailin Zhu, Guan Chen, Yueyi Ren, Kenji Iemura, Kozo Tanakaα-tubulin (B5-1-2; Merck, T5168), p16 (2D9A12; Abcam, ab54210), IL-6 (E-4; Santa Cruz Biotechnology, sc-28343), alpha smooth muscle actin (α-SMA, 1A4; Abcam, ab7817), and phospho-Histone H2A.X (Ser139 (γ-H2AX),

(6) Dexmedetomidine regulates sleep rhythm and alleviates neuroinflammation in rats under high-altitude hypoxiaJournal of Physiology and BiochemistryNovember 12, 2025Shanshan Liu, Long Feng, Haining Yang, Yi Liu, Wen Sun, Yongzhe Liu, Longhe Xuat room temperature and then incubated at 4℃ for 60 min with primary antibodies against IL-6 (1:100, sc-28343, Santa Cruz, USA) and IBA-1 (1:100, DF6442, Affinity Biosciences, China). Following primary incubation,

(7) Cilastatin Modulates DPEP1- and IQGAP1-Associated Neuro-Glio-Vascular Inflammation in Oxaliplatin-Induced Peripheral NeurotoxicityCellsAugust 20, 2025Rita Martín-Ramírez, María Ángeles González-Nicolás, Karen Álvarez-Tosco, Félix Machín, Julio Ávila, Manuel Morales, Alberto Lázaro, Pablo Martín-VasalloUSA",sc-52B83 Anti-IL-6,Anti-IL-6,Mouse monoclonal,1:200,"Santa Cruz Biotechnology Dallas, TX, USA",sc-28343 Anti-Laminin,Anti-Laminin,Mouse monoclonal,1:200,"Santa Cruz Biotechnology Dallas, TX, USA",sc-365962 Anti-α-Actin,Anti-α-Actin,Mouse

(8) Protective effects of Alamandine against doxorubicin-induced liver injury in ratsBMC Pharmacol ToxicolMay 3, 2025Ava Soltani Hekmat, Maryam Hekmat, Sepehr Ramezanipour, Kazem Javanmardiserum. The tissue sections were then immunostained with primary antibodies against IL-6 (catalog no. sc-28343; Santa Cruz Biotechnology, Inc.), IL-1 (catalog no. sc-32294; Santa Cruz Biotechnology, Inc.), P53 (catalog

(9) Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic miceFrontiers in Cell and Developmental BiologyJanuary 22, 2025Wanying Cheng, Cenzhu Wang, Meican Ma, Yu ZhouBAX (50599-2-lg, Proteintech), ICAM1 (10831-1-AP, Proteintech), TNF (17590-1-AP, Proteintech), IL6 (sc-28343, Santa Cruz), p-S6K (sc-8416, Santa Cruz), S6K (sc-8418, Santa Cruz), Tubulin (66031-1-Ig, Proteintech)

(10) Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in miceCellular and Molecular Life SciencesDecember 1, 2024Yue Zhang, Meng Yuan, Wenbin Cai, Weiyan Sun, Xuelian Shi, Daiqi Liu, Wenhua Song, Yingqun Yan, Tienan Chen, Qiankun Bao, et al.(ab76533), α-SMA (ab7817, ab124964) and Ki67 (ab15580) (all Abcam, Cambridge, UK); PTGIS (sc-293247), IL-6 (sc-28343) (all Santa cruz Biotechnology, Dallas, TX, USA); Alexa Fluor 594-conjugated wheat germ agglutinin (W11262;

(11) Association of DNA methylation/demethylation with the functional outcome of stroke in a hyperinflammatory stateNeural Regeneration ResearchOctober 1, 2024Yubo Wang, Ling Zhang, Tianjie Lyu, Lu Cui, Shunying Zhao, Xuechun Wang, Meng Wang, Yongjun Wang, Zixiao LiCell Signaling Technology, Cat# 12242, RRID: AB_2715503), IL-6 (mouse, 1:500, Santa Cruz Biotechnology, Cat# sc-28343, RRID: AB_627805), NF-kβ (mouse, 1:500, Santa Cruz Biotechnology, Cat# sc-8008, RRID: AB_628017) and

(12) Characterization of Tissue Immunity Defense Factors of the Lip in Primary Dentition Children with Bilateral Cleft Lip PalateJournal of Personalized MedicineSeptember 11, 2024Laura Ozola, Mara PilmaneUK" CD 163,ab87099,1:200,Abcam,"Cambridge, UK" IL-4,orb10908,1:100,Biorbyt,"Cambridge, UK" IL-6,sc-28343,1:100,Santa Cruz Biotechnology Inc.,"Santa Cruz, CA, USA" IL-10,orb100193,1:600,Biorbyt LLC,"St Louis,

(13) Reduction of oxidative stress response and protection of liver and renal cell functions by reduced glutathione in lower limb arterial ischemia–reperfusion in New Zealand white rabbits with high triglyceride levelsHeliyonJune 30, 2024Xiaochen Wang, Hailei Sun, Guangcun Cheng, Jianjun Gesites included membrane and secreted proteins, and the dilution ratio was 1:150. The IL-6 antibodie Sc-28343 from Santa Cruz Biotechnology was used. The expression site was composed of secretory proteins, and

(14) Effect of apigetrin in pseudo-SARS-CoV-2-induced inflammatory and pulmonary fibrosis in vitro modelScientific reportsJune 24, 2024Han H, Kim JE, Lee HJ.USA), after which the membranes were incubated with primary antibodies against IL-6 (ratio 1:2000, Cat: SC-28343, Santa Cruz, Dallas, TX, USA), Spike1 (ratio 1:1000, Cat: 99423, Cell Signaling, Danvers, MA, USA),

(15) AZD1390, an ataxia telangiectasia mutated inhibitor, attenuates microglia-mediated neuroinflammation and ischemic brain injuryCNS neuroscience & therapeuticsApril 1, 2024Lan Z, Qu LJ, Liang Y, Chen LQ, Xu S, Ge JW, Xue ZW, Bao XY, Xia SN, Yang HY, et al.non‐fat milk for 2 h and incubated with primary antibodies against IL‐1β (sc52012, Santa Cruz), IL‐6 (sc‐28343, Santa Cruz), TNF‐α (sc‐52746, Santa Cruz), iNOS (BS40374, Bioworld Biotechnology), p‐NF‐κB/p‐P65 (3033,

(16) Leptin-Mediated Induction of IL-6 Expression in Hofbauer Cells Contributes to Preeclampsia PathogenesisInternational journal of molecular sciencesDecember 21, 2023Ozmen A, Nwabuobi C, Tang Z, Guo X, Larsen K, Guller S, Blas J, Moore M, Kayisli UA, Lockwood CJ, et al.1:1000 Phospho-p65,Cell Signaling #3033,WB 1:1000 Total-p65,Cell Signaling #8242,WB 1:1000 IL-6,Santa Cruz #sc-28343,WB 1:1000 Β-Actin,Cell Signaling #5125,WB 1:1000 IL-6,R&D #AF-206-NA,IHC: 10 μg/mL LepR (ObR),Santa Cruz

(17) L-citrulline attenuates lipopolysaccharide-induced inflammatory lung injury in neonatal ratsPediatric researchNovember 1, 2023Ivanovski N, Wang H, Tran H, Ivanovska J, Pan J, Miraglia E, Leung S, Posiewko M, Li D, Mohammadi A, et al.

(18) N-(2-hydroxy phenyl) acetamide ameliorate inflammation and doxorubicin-induced nephrotoxicity in ratsInternational immunopharmacologyOctober 1, 2023Shams S, Lubbad LI, Simjee SU, Jabeen A.

(19) Role of TGF-beta1 and TNF-alpha1 produced by neoplastic cells in the pathogenesis of fibrosis in patients with hematologic neoplasmsJournal of clinical and experimental hematopathology : JCEHJune 28, 2023Takizawa H, Araki Y, Fujishiro M, Tomita S, Kishikawa S, Hashizume A, Mitsumori T, Nitta H, Iizuka-Honma H, Sawada T, et al.INFγ: Abcam ab9657 polyclonal; VGEF: Proteintech 19003-1-AP poly clonal; IL-6: SANTA CRUZ BIOTECHNOLOGY Sc-28343; IL-2: Proteintech 60306-1-IG mouse monoclonal 2F11C5. Positive and negative immunostaining was determined

(20) Augmented temperature fluctuation aggravates muscular atrophy through the gut microbiotaNature communicationsJune 13, 2023Liu Y, Guo Y, Liu Z, Feng X, Zhou R, He Y, Zhou H, Peng H, Huang Y.1:500), anti-mTOR (CST, 2983, 1:500), anti-TNFα (Santa Cruz, sc-52746, 1:1000), anti-IL6 (Santa Cruz, sc-28343, 1:1000), anti-GAPDH (OriGene, TA802519, 1:5000). After incubation overnight, secondary antibodies (Invitrogen,

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IL-6 (E-4) Antibody

IL-6 (E-4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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IL-6 (E-4) Antibody from Santa Cruz Biotechnology, Inc.

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