The Bcl-10 Polyclonal Antibody, PE-Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to BCL10, and BCL10 immune signaling adaptor. This antibody recognizes Homo Sapiens, and Human antigen. The Bcl-10 Polyclonal Antibody, PE-Cy7 Conjugated has been shown to work in the following applications: Western Blot.
Description
Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101)