The ADAMTS4 Polyclonal Antibody, Cy5.5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ADAMTS4. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ADAMTS4 Polyclonal Antibody, Cy5.5 Conjugated has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-:-Ala-393' site