The IRS-3 Polyclonal Antibody, PE Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to Insulin Receptor Substrate 3, and IRS3. This antibody recognizes Mouse, Rat, and Porcine antigen. The IRS-3 Polyclonal Antibody, PE Conjugated has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2