Fyn (15) Antibody sc-434 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemFyn (15) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-434
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
FormatPurified
Antibody TypePrimary Antibodies
Clone15
Hostmouse
TargetFyn
IsotypeIgG1
NCBI Gene Aliasesp59-FYN, SYN, SLK
ClonalityMonoclonal
NCBI Full Gene NameFyn proto-oncogene, FYN proto-oncogene, Src family tyrosine kinase

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entryJournal of VirologyAugust 19, 2025Ruiya Lian, Xueer Dou, Na Wang, Shasha Li, Jingying Xie, Xiangrong Li, Yanmei Yang, Yanqiao Wen, Huixia Li, Ruofei Feng(sc-8056), phospho-Src (sc-81521) targeting Tyr419 (human) or Tyr424 (mouse), Ezrin (sc-271541), Fyn (sc-434), phospho-Fyn (sc-377555), Caveolin-1 (sc-53564), phospho-Caveolin-1 (sc-373836), and Rab5 (sc-46692)

(2) FYN-mediated phosphorylation of BCKDK at Y151 promotes GBM proliferation by increasing the oncogenic metabolite N-acetyl-L-alanineHeliyonAugust 15, 2024Zou L, Wang W, Huang W, Ni X, Li W, Cheng Y, Tian Q, Liu L, Zhu F, Duan Q.Number,Source Anti-BCKDK (E-12),sc-374425,"Santa Cruz Technology (CA, USA)" "Santa Cruz Technology (CA, USA)",Anti-Fyn,sc-434 Anti-MEK1/2,#8727,"Cell Signaling Technology (Danvers, MA, USA)" "Cell Signaling Technology (Danvers,

(3) Thyroid hormone T3 induces Fyn modification and modulates palmitoyltransferase gene expression through αvβ3 integrin receptor in PC12 cells during hypoxiaTranslational neuroscienceJanuary 1, 2024Kvergelidze E, Barbakadze T, Bátor J, Kalandadze I, Mikeladze D.palmitoylated Fyn and palmitoylated p-Fyn, samples (0.3 mg) were immunoprecipitated with anti-Fyn (sc-434; Santa Cruz Biotechnology, USA) or anti-p-Fyn (sc-377555; Santa Cruz Biotechnology, USA) primary antibody

(4) Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathyNeuropathology and applied neurobiologyAugust 1, 2023van Hummel A, Taleski G, Sontag JM, Feiten AF, Ke YD, Ittner LM, Sontag E.

(5) Aberrant palmitoylation caused by a ZDHHC21 mutation contributes to pathophysiology of Alzheimer's diseaseBMC medicineJune 26, 2023Li W, Pang Y, Wang Y, Mei F, Guo M, Wei Y, Li X, Qin W, Wang W, Jia L, et al.antibodies were used in this study: anti-Fyn (catalogue no. ab1881, Abcam), anti-Fyn (catalog no.: sc-434, Santa Cruz Biotechnology), anti-APP (catalog no.: ab32136, Abcam), anti-actin (catalog no.: TA-09,

(6) DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological MalignanciesCellsApril 6, 2023Kikuchi S, Wada A, Kamihara Y, Okazaki K, Jawaid P, Rehman MU, Kobayashi E, Susukida T, Minemura T, Nabe Y, et al.monoclonal, mouse, sc-433 (Santa Cruz Biotechnology), an anti-Fyn antibody (15), monoclonal, mouse, sc-434 (Santa Cruz Biotechnology), an anti-c-Fgr antibody (B-8), monoclonal, mouse, sc-166079 (Santa Cruz Biotechnology),

(7) FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancerJournal of experimental & clinical cancer research : CRApril 4, 2023Peng S, Yin Y, Zhang Y, Zhu F, Yang G, Fu Y.M20003s) were purchased from Abmart (Abmart Pharmaceutical Technology Co, Ltd.). FYN (1:1000, sc-73388, sc-434),TOPK(sc-293028) were purchased from Santa Cruz, Inc. (Santa Cruz Biotech.,USA).FYN(1:1000,ab184276,ab119855)

(8) 3,5,3'-Triiodo-L-Thyronine Regulates Actin Cytoskeleton Dynamic in The Differentiated PC-12 Cells during Hypoxia through An αvβ3 IntegrinCell JApril 1, 2023Tamar Barbakadze, Elisabed Kvergelidze, Judit Bátor, József Szeberényi, David Mikeladzeanti-p-cofilin1at ratio 1:500 (sc-271921, Santa Cruz Biotechnology, USA), anti-Fyn at ratio 1:500 (sc-434, Santa Cruz Biotechnology,USA), anti-p-Fyn at ratio 1:500 (sc-377555, Santa Cruz Biotechnology, USA).

(9) 3,5,3'-Triiodo-L-Thyronine Regulates Actin Cytoskeleton Dynamic in The Differentiated PC-12 Cells during Hypoxia through An αvβ3 IntegrinCell journalApril 1, 2023Barbakadze T, Kvergelidze E, Bátor J, Szeberényi J, Mikeladze D.anti-p-cofilin1at ratio 1:500 (sc-271921, Santa Cruz Biotechnology, USA), anti-Fyn at ratio 1:500 (sc-434, Santa Cruz Biotechnology,USA), anti-p-Fyn at ratio 1:500 (sc-377555, Santa Cruz Biotechnology, USA).

(10) Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBNCellsFebruary 1, 2023Chang HW, Sim KH, Lee YJ.GAPDH (#2118) were purchased from Cell Signaling Technology (Danvers, MA). Antibodies against Fyn (#sc-434), IgG (#sc-2025, 2027), IKK (#sc-7607), LAT (#sc-53550), Lyn (#sc-376100), PLCγ1 (#sc-7290), SHP-1 (#sc-7289),

(11) G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4(+) T Cell ActivationJournal of immunology (Baltimore, Md. : 1950)November 2, 2022Murata R, Kinoshita S, Matsuda K, Kawaguchi A, Shibuya A, Shibuya K.

(12) Tau differentially regulates the transport of early endosomes and lysosomesMolecular biology of the cellNovember 1, 2022Balabanian L, Lessard DV, Swaminathan K, Yaninska P, Sébastien M, Wang S, Stevens PW, Wiseman PW, Berger CL, Hendricks AG.

(13) Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in miceCell reports. MedicineApril 19, 2022Shiwaku H, Katayama S, Kondo K, Nakano Y, Tanaka H, Yoshioka Y, Fujita K, Tamaki H, Takebayashi H, Terasaki O, et al.anti-Polysialic Acid-NCAM antibody clone 2-2B (1:1000, MAB5324, Millipore), anti-Fyn antibody (1:1000, sc-434, Santa Cruz Biotechnology), anti-FAK antibody (1:1000, 3285, Cell Signaling Technology), anti-Phospho-FAK (Tyr397

(14) Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cellsPLoS pathogensApril 1, 2022Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, et al.#13089), anti-NFATc1 (Santa Cruz #sc-7294), anti-NFATc2 (Cell Signaling #4389), anti-FYN (Santa Cruz #sc-434), anti-TNFRSF9 (Cell Signaling #34594), anti-CD9 (Cell Signaling #13174), anti-HLA DR/MHC class II (Santa Cruz

(15) IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal subnucleus caudalisBrain, behavior, and immunityJanuary 1, 2022Kimura Y, Hayashi Y, Hitomi S, Ikutame D, Urata K, Shibuta I, Sakai A, Ni J, Iwata K, Tonogi M, et al.

(16) Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific statesCell reportsNovember 30, 2021Lautz JD, Tsegay KB, Zhu Z, Gniffke EP, Welsh JP, Smith SEP.Component,Clone,Supplier,Cat#,RRID CaMKII,IP,6G9,ThermoFisher,MA1-048,AB_325403 CaMKII,Probe,polyC6970,Sigma,C6974,AB_258984 Fyn,IP,Fyn15,Santa Cruz,sc-434,AB_627642 Fyn,Probe,Fyn59,Biolegend,626502,RRID:AB_2278824 PI3K p85,IP,U5,ThermoFisher,MA1-74183,AB_2163452 PI3K

(17) Roles of adenosine A(1) receptors in the regulation of SFK activity in the rat forebrainBrain and behaviorAugust 1, 2021Mao LM, Wang JQ.milk‐PBS 0.1% Tween‐20 Fyn,Amino acids 85‐206 of human Fyn,"Santa Cruz Biotechnology, mouse monoclonal, sc‐434, AB_627642",1,3% Nonfat milk‐PBS 0.1% Tween‐20 Src,Recombinant fusion protein corresponding to residues

(18) Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEGBMC biologyNovember 6, 2020Espinoza S, Arredondo SB, Barake F, Carvajal F, Guerrero FG, Segovia-Miranda F, Valenzuela DM, Wyneken U, Rojas-Fernández A, Cerpa W, et al.antiSynapsin I (Abcam Cat#ab8, RRID:AB_2200097, 1:10, 000), mouse anti-Fyn (Santa Cruz Biotechnology Cat#sc434, RRID:AB_627642, 1:1000), mouse anti-Src (17AT28) (Santa Cruz Biotechnology Cat#sc-130124, RRID:AB_ 2196197,

(19) Neuroprotection by Neurotropin through Crosstalk of Neurotrophic and Innate Immune Receptors in PC12 CellsInternational journal of molecular sciencesSeptember 4, 2020Fukuda Y, Nakajima K, Mutoh T.against Trk (clone C-14; Santa Cruz Biotechnology, Santa Cruz, CA, USA; RRID: AB_632554; α-Trk), Fyn (sc-434; Santa Cruz Biotechnology; RRID: AB_627642; α-Fyn) and protein A-Sepharose conjugate at 4 ◦ C overnight.

(20) TICAM2-related pathway mediates neutrophil exhaustionScientific reportsSeptember 1, 2020Lin R, Zhang Y, Pradhan K, Li L.(Tyr416) (1:20 dilution; ThermoFisher, no. MA5-28055), or anti-Fyn (1:50 dilution; Santa Cruz, no. sc-434 FITC). Surface phenotype, transcription factor and intracellular protein levels of Ly6G+ neutrophils

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Fyn (15) Antibody

Fyn (15) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Fyn (15) Antibody from Santa Cruz Biotechnology, Inc.

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