The EDG4 Polyclonal Antibody, Biotin Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to LPAR2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The EDG4 Polyclonal Antibody, Biotin Conjugated has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues