Raf-1 (E-10) Antibody sc-7267 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRaf-1 (E-10) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-7267
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneE-10
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
ClonalityMonoclonal
Hostmouse
FormatPurified
NCBI Gene Aliasesc-Raf, D830050J10Rik, 6430402F14Rik, CMD1NN, cRaf, CRAF, Craf1, v-Raf, Raf-1, NS5
NCBI Full Gene NameRaf-1 proto-oncogene, serine/threonine kinase, v-raf-leukemia viral oncogene 1
TargetRaf-1
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) GPR35 protects against reperfusion injury in ischemic stroke by binding with the CR2 domain of Raf1Journal of NeuroinflammationFebruary 10, 2026Xiaojun Li, Qi Wang, Qingyu Cheng, Jingyong Zhou, Tingting Qu, Jianling Xu, Yuming Du, Bowen Miao, Yongquan Chen, Weidong Yao, et al.Invitrogen), GFAP (1:200, GB12096-100, Servicebio), CD68 (1:200, ab283654, Abcam), or Raf1 (1:100, sc7267, Santa Cruz), followed by DyLight-conjugated secondary antibodies (1:200, E032210-01, E032420-01, EarthOx)

(2) Spatiotemporal regulation of MKK4 dictates switch-like JNK activation and binary cell-fate decisionsNature CommunicationsJanuary 8, 2026Hisashi Moriizumi, Takanori Nakamura, Yuji Kubota, Ryosuke Hiranuma, Youngmin Cho, Toru Kawanishi, Hiroyuki Takeda, Takashi Suzuki, Mutsuhiro Takekawadilution); anti-Myc 9E10 (sc-40, 1:500 dilution), anti-MEK1 H-8 (sc-6250, 1:200 dilution), anti-Raf-1 E-10 (sc-7267, 1:200 dilution) (Santa Cruz Biotechnology); anti-MKK4 5C10 (Cell Signaling Technology, 3346, 1:100

(3) USP10-mediated deubiquitination and activation of KRAS mutants promotes colorectal cancer via a novel USP10/KRAS positive feedback circuitActa Pharmaceutica Sinica BJanuary 1, 2026Tao Yuan, Weihua Wang, Ruilin Wu, Yue Liu, Junwei Fu, Jiamin Du, Meijia Qian, Jia’er Wang, Yubo Zhang, Wencheng Kong, et al.Antibodies against KRAS (#sc-30, RRID: AB_627865), ubiquitin (Ub) (#sc-8017, RRID: AB_628423), and RAF1 (#sc-7267, RRID: AB_628196) were obtained from Santa Cruz Biotechnology (Dallas, TX, USA). Antibodies against

(4) ZDHHC2 promoted antimycobacterial responses by selective autophagic degradation of B-RAF and C-RAF in macrophagesSci AdvJanuary 24, 2025Junli Sheng, Xiaolong You, Dingnai Nie, Yuling Fu, Qiao Ling, Xiaodan Yang, Yitian Chen, Li Ma, Shengfeng HuProteintech, 60004-1-Ig), B-RAF (Santa Cruz Biotechnology, sc-5284), C-RAF (Santa Cruz Biotechnology, sc-7267), TBK1 (CST, 3013s), p-TBK1 (CST, 5483s), JNK (CST, 9252s), p-JNK (CST, 9251s), P65 (CST, 4764s), p-P65

(5) Umbelliferone as an effective component of Rhodiola for protecting the cerebral microvascular endothelial barrier in cSVDFrontiers in pharmacologyJanuary 1, 2025Tang L, Cheng H, Yang Q, Xie Y, Zhang Q.1:1000), p-ERK (Cell Signaling Technology, 4370S, Unites States, 1:2000), Raf (Santa Cruz Biotechnology, sc-7267, Unites States, 1:200), Mek (Santa Cruz Biotechnology, sc-17820, Unites States, 1:100), PI3K (Abcam,

(6) TCF19 promotes cell proliferation and tumor formation in lung cancer by activating the Raf/MEK/ERK signaling pathwayTranslational OncologyJuly 1, 2024Yahui Tian, Shaowei Xin, Zitong Wan, Honghong Dong, Lu Liu, Zhenzhen Fan, Tian Li, Fujun Peng, Yanlu Xiong, Yong HanCell Signaling Technology), anti-p-ERK1/2 (diluted 1:1000, #4370, Cell Signaling Technology), anti-Raf-1 (diluted 1:500, sc-7267, Santa Cruz, USA), anti-p-Raf-1 (diluted 1:500, sc-271,919, Santa Cruz, USA), anti-FLAG (diluted 1:1000,

(7) Liprin‐α1 contributes to oncogenic MAPK signaling by counteracting ERK activityMolecular OncologyJanuary 24, 2024Henna Pehkonen, Artemis Filippou, Juho Väänänen, Iida Lindfors, Mira Vänttinen, Philipp Ianevski, Anne Mäkelä, Pauliina Munne, Juha Klefström, Sanna Toppila‐Salmi, et al.rabbit mAb (#9154), MEK1/2 (#8727) rabbit mAb (Cell Signaling, Danvers, MA, USA), mouse mAb RAF1 (E10, sc7267) (Santa Cruz, Dallas, TX, USA), rabbit mAb RAF1 (Abcam, Cambridge, UK), mouse monoclonal vinculin (Sigma‐Aldrich),

(8) Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived TumorsCancer Res CommunDecember 28, 2023Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, et al.no A5441-.2ML from Sigma-Aldrich; KRAS (catalog no. OP24, from EMDMillipore), and RAF1 (catalog no. sc-7267, Santa Cruz Biotechnology), horseradish peroxidase–conjugated goat anti-GST antibody (catalog no. A190-121P

(9) Proteomic Mapping of the Interactome of KRAS Mutants Identifies New Features of RAS Signalling Networks and the Mechanism of Action of SotorasibCancersAugust 17, 2023Nolan A, Raso C, Kolch W, Kriegsheim AV, Wynne K, Matallanas D.

(10) Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cellsCell reportsJuly 25, 2023Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, et al.,Cell Signaling Technology,Cat# 2524; RRID: AB_331743 Mouse monoclonal anti-Raf-1 (E-10),Santa Cruz Biotechnology,Cat# sc-7267; RRID: AB_628196 Mouse monoclonal anti-Vinculin,Proteintech,Cat# 66305–1-Ig; RRID: AB_2810300 Mouse

(11) HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesisScience advancesJune 9, 2023Jiang Q, Zhang D, Liu J, Liang C, Yang R, Zhang C, Wu J, Lin J, Ye T, Ding L, et al.AB_10920395), anti-SOS1 (sc-17793; RRID: AB_628269), anti-SHC (sc-967; RRID: AB_628249), anti-RAF1 (sc-7267; RRID: AB_628196), anti-MEK1/2 (sc-81504; RRID: AB_1126111), anti–c-myc (sc-373712; RRID: AB_10916994),

(12) HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 DegradationCellular and molecular gastroenterology and hepatologyJanuary 1, 2023Yuan J, Lv T, Yang J, Wu Z, Yan L, Yang J, Shi Y, Jiang L.previously described.19 Anti-HDLBP (Proteintech, 15406-1-AP, 1:100) and Anti-RAF1 (Santa Cruz Biotechnology, sc-7267, Dallas, Tx, 1:50) were used. Mouse Studies Six-week-old female BALB/c nude mice were purchased from

(13) USP7 regulates the ERK1/2 signaling pathway through deubiquitinating Raf-1 in lung adenocarcinomaCell death & diseaseAugust 10, 2022Park HB, Hwang S, Baek KH.USA), anti-p-Raf-1 (Cat #sc-271928, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-Raf-1 (Cat #sc-7267, Santa Cruz Biotechnology, Santa Cruz, CA, USA), anti-Raf-1 (Cat #LF-PA0195, Ab Frontier, Seoul, Korea),

(14) HIPK2 Cooperates with KRAS Signaling and Associates with Colorectal Cancer ProgressionMolecular cancer research : MCRMay 4, 2022Di Segni M, Virdia I, Verdina A, Amoreo CA, Baldari S, Toietta G, Diodoro MG, Mottolese M, Sperduti I, Moretti F, et al.

(15) Conjugation of VEGFR1/R2-targeting peptide with gold nanoparticles to enhance antiangiogenic and antitumoral activityJournal of nanobiotechnologyJanuary 4, 2022Zanjanchi P, Asghari SM, Mohabatkar H, Shourian M, Shafiee Ardestani M.(sc-538), p-P38 (sc-17852), PI 3-kinase p85α (B-9) (sc-1637), mTOR (sc-517464), p-mTOR (sc-293133), Raf (sc-7267) and mouse anti-rabbit IgG-HRP (sc-2357), mouse anti-rabbit IgG-FITC (sc-2359) and mouse anti-rabbit IgG-PE

(16) The relationship of vascular endothelial growth factor and osteopontin expression with 3-year progression-free survival of locally advanced nasopharyngeal cancer patients treated with platinum-based chemoradiationContemporary oncology (Poznan, Poland)January 1, 2022Irawan C, Nufus H, Rachmadi L, Harimurti K, Munandar A, Yunus RE.immunohistochemical (IHC) staining for VEGF (Figure 1) measurement was performed with mouse VEGF (C-1: sc-7267 Santa Cruz monoclonal antibody with 1: 100 dilution). It is important to note that IHC staining for

(17) DDX3 acts as a tumor suppressor in colorectal cancer as loss of DDX3 in advanced cancer promotes tumor progression by activating the MAPK pathwayInternational journal of biological sciencesJanuary 1, 2022Shen L, Zhang J, Xu M, Zheng Y, Wang M, Yang S, Qin B, Li S, Dong L, Dai F.sc-30; Santa Cruz, Dallas, Texas, USA), anti-p-Raf-1 (1:100; sc-271929; Santa Cruz), anti-Raf-1 (1:200; sc-7267; Santa Cruz), anti-p-MEK1/2 (1:1000; 3958; CST), anti-MEK1/2 (1:1000; 13033; CST), anti-p-β-catenin

(18) Cyclin-dependent kinase inhibitor 1B acts as a novel molecule to mediate testosterone synthesis and secretion in mouse Leydig cells by luteinizing hormone (LH) signaling pathwayIn vitro cellular & developmental biology. AnimalAugust 1, 2021Guo H, Luo X, Sun L, Li J, Cui S.

(19) YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathwaysOncogenesisMay 4, 2021Ou WB, Lundberg MZ, Zhu S, Bahri N, Kyriazoglou A, Xu L, Chen T, Mariño-Enriquez A, Fletcher JA.(#9102), and YAP/TAZ (#8418) were from Cell Signaling Technology (Beverly, MA), whereas those for RAF1 (sc-7267), CTGF (sc-14939) and CYR61 (sc-13100) were from Santa Cruz Biotechnology (Santa Cruz, CA). Monoclonal

(20) Combination of curcumin and ginkgolide B inhibits cystogenesis by regulating multiple signaling pathwaysMolecular medicine reportsMarch 1, 2021Li Y, Gao J, Yang X, Li T, Yang B, Aili A.

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2/20/2018Great Antibody For Western Blotting Shikha SainiRaf-1 is a Ser/Thr kinases intrinsic kinase activity. Mutation in Raf protein is often observed in several human malignancies. We determined its levels in MCF7 cells after treatment with the drug 1 ... Read Review

Raf-1 (E-10) Antibody

Raf-1 (E-10) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (124)

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Raf-1 (E-10) Antibody from Santa Cruz Biotechnology, Inc.

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