CD8-α (D-9) Antibody sc-7970 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCD8-α (D-9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-7970
Antibody TypePrimary Antibodies
Reactivitymouse, rat, human
Quantity200 µg/ml
CloneD-9
ApplicationsWB, IP, IF, IHC(P), ELISA
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
ClonalityMonoclonal
NCBI Gene AliasesLy-35, Ly-B, CD8alpha, Ly-2, Leu2, p32, Lyt-2, CD8
NCBI Full Gene NameCD8 subunit alpha
TargetCD8-alpha
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Oral Administration of Withaferin A Increases Infiltration of CD4+ Helper T Cells in a Mouse Model of Mammary TumorJ Cancer PrevApril 30, 2026Eun-Ryeong Hahm, Krishna B. Singh, Shivendra V. SinghFoxP3 (cat. # 320008; RRID: AB_492980) were purchased from BioLegend. An antibody against CD8α (cat. # sc-7970; RRID: AB_627208) for immunohistochemistry was purchased from Santa Cruz Biotechnology. C3(1)-TAg mice

(2) PrP C Glycoprotein Modulates Atmospherically Relevant Artificial Particulate Matter-Induced Development of Lung Cancer in MiceEnvironmental Science & TechnologyApril 7, 2026Thi Thu Trang Kieu, Hyun-Jaung Sim, Govinda Bhattarai, Han-Sol So, Jeong-Chae Lee, Sung-Ho Kook-Santa Cruz Biotechnology), TNFα (AB1793-Abcam), 8-OHdG (Ab62623-Abcam), CD4 (25229-Cell Signaling), CD8 (sc-7970-Santa Cruz Biotechnology) and VEGF-A (BS2853-Bio World). After washing, the slides were incubated with

(3) Restoration of Immune Surveillance in Prostate Cancer Prevention by Sulforaphane in Hi‐Myc MiceMolecular CarcinogenesisMarch 9, 2026Krishna B. Singh, Eun‐Ryeong Hahm, Joshi J. Alumkal, Shivendra V. Singhor Corning (Manassas, VA). Antibodies against CD4 (cat. # sc-19641; RRID_AB627055) and CD8α (cat. # sc-7970; RRID:AB_627208) were purchased from Santa Cruz Biotechnology (Dallas, TX). An antibody against perforin

(4) Inhibiting the Secreted RGDKGE Collagen Peptide Selectively Controls CD8+ T-Cell Migration on Denatured Collagen-IV and Enhances Their Accumulation in TumorsThe American Journal of PathologyFebruary 1, 2026XiangHua Han, Jennifer M. Caron, Peter C. BrooksMA), and anti–phosphorylated Tyr-747 β3 antibody was from Santa Cruz (Dallas TX). Anti-CD4, anti-CD8α (SC-7970), and anti-actin antibody are from Santa Cruz. The Super Signal Pico Plus Western blot analysis development

(5) Prolonged skin allograft survival by rM180 amelogenin in a murine skin transplantation modelFrontiers in ImmunologyOctober 27, 2025Miyu Shida, Terukazu Sanui, Karen Yotsumoto, Jinfeng Li, Mwannes Ahmad, Meng Xiao, Ziyu Wang, Chikako Hayashi, Yuki Nishimura, Takanori Shinjo, et al.anti-rabbit CD4 antibody (ab287724; Abcam, Cambridge, UK), at 1:20 dilution, Anti-mouse CD8 alpha antibody (sc-7970, Santa Cruz Biotechnology, Dallas, TX, USA) at 1:250 dilution, Anti-MHC class II ([MRC OX-6]; Abcam)

(6) Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expressionCell Death DisAugust 18, 2025Jiazhen Li, Chenying Liu, Xiaolong Qian, Xiaozi Wang, Hui Sun, Lu Wang, Huiqin Xue, Yuanming Song, Jiamei Liu, Yafang Zhao, et al.A + HLA B rabbit mAb (Abcam, ab134189), 1:4000 dilution; CD8-α mouse mAb (Santa Cruz Biotechnology, sc-7970), 1:100 dilution; TNF-α mouse mAb (proteintech, 26405-1-AP), 1:200 dilution; Phospho-Stat1 rabbit mAb

(7) Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapyJournal of experimental & clinical cancer research : CRJuly 2, 2025Zhao H, Zhang Z, Zhang C, Ma H, Wan Q, Zhao X, Wang X, Yan M, Guo H, Zhang J, et al.antibody (Novus Biologicals, 1:50, NB100-105), anti-CD8a antibody (Santa Cruz Biotechnology, 1:50, sc-7970), anti-GZMB antibody (Santa Cruz Biotechnology, 1:50, sc-8022), anti-PDCD1 antibody (eBiosciences, 1:100,

(8) Development of a bacteria-nanosapper for the active delivery of ZIF-8 particles containing therapeutic genes for cancer immune therapyActa Pharmaceutica Sinica BDecember 1, 2024Yiting Qiao, Miao Luo, Yufei Wang, Haoxiang Qi, Menglan Wang, Yunxin Pei, Mengqing Sun, Zhengguo Zhang, Jiacheng Huang, Pengyu Gong, et al.(Cell Signaling Technology Inc., #9664S, Danvers, MA, USA), CD8α antibody (Santa Cruz Biotechnology Ltd., #sc-7970, Dallas, TX, USA), CD4 antibody (Abcam Ltd., #ab288724, Cambridge, UK), F4/80 antibody (Abcam Ltd.,

(9) Resistance training suppresses accumulation of senescent fibro-adipogenic progenitors and senescence-associated secretory phenotype in aging rat skeletal muscleGeroScienceSeptember 19, 2024Yung-Li Hung, Ayami Sato, Yuka Takino, Akihito Ishigami, Shuichi MachidaTris-buffered saline/Tween 20 (TBST) for 1 h at 25 °C and then incubated with anti-CD8α primary antibody (sc-7970; Santa Cruz Biotechnology. Inc, Dallas, TX, USA) at 4 °C overnight. The blots were washed three times

(10) Molecular Iodine Improves the Efficacy and Reduces the Side Effects of Metronomic Cyclophosphamide Treatment against Mammary Cancer ProgressionInternational Journal of Molecular SciencesAugust 13, 2024Evangelina Delgado-González, Ericka de los Ríos-Arellano, Brenda Anguiano, Carmen AcevesUSA)",1:250 Mouse monoclonal anti-GPx,"ST1000 (Calbiochem, San Diego, CA, USA)",1:200 Mouse monoclonal anti-CD8,"sc-7970 (Santa Cruz Biotechnology, Dallas, TX, USA)",1:100 Rabbit polyclonal anti-CD34,"ab182981 (Abcam, Cambridge,

(11) Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunityCell reports. MedicineMay 21, 2024Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, et al.10904-1-AP; RRID: AB_2224377 Anti-CD8,Abcam,Cat# ab217344; RRID: AB_2890649 Anti-CD8,Santa Cruz,Cat# sc-7970; RRID: AB_627208 Anti-P65,CST,Cat# 8242; RRID: AB_10859369 Anti-Phospho-P65,CST,Cat# 3033; RRID: AB_331284 Anti-Tubulin,Ray

(12) Novel Findings on CCR1 Receptor in CNS Disorders: A Pathogenic Marker Useful in Controlling Neuroimmune and Neuroinflammatory Mechanisms in Parkinson's DiseaseInternational journal of molecular sciencesApril 14, 2024Repici A, Capra AP, Hasan A, Bulzomì M, Campolo M, Paterniti I, Esposito E, Ardizzone A.Cruz, CA, USA), CD-4 (1:100; sc-514571 Santa Cruz Biotechnology, Santa Cruz, CA, USA), and CD-8 (1:100; sc-7970 Santa Cruz Biotechnology, Santa Cruz, CA, USA). The secondary fluorescent antibodies Alexa Flour 488

(13) Immunotherapy with STING and TLR9 agonists promotes synergistic therapeutic efficacy with suppressed cancer-associated fibroblasts in colon carcinomaFrontiers in ImmunologyOctober 13, 2023Sare Hajiabadi, Soodeh Alidadi, Zohreh Montakhab Farahi, Mohammad M. Ghahramani Seno, Hamidreza Farzin, Alireza Haghparastmin with different concentrations of primary antibodies, e.g., anti-CD8-α (1 out of 200) (cat. number sc-7970; RRID: AB_627208; Santa Cruz Biotechnology, Dallas, TX, USA), anti-cleaved caspase 3 (1 out of 300)

(14) Anti-Inflammatory and Antipruritic Effects of Remote Ischaemic Postconditioning in a Mouse Model of Experimental Allergic Contact DermatitisMedicina (Kaunas)October 12, 2023Ozgur Gunduz, Melike Sapmaz-Metin, Ruhan Deniz Topuz, Oktay Kaya, Cetin Hakan Karadag, Ahmet Ulugolincubated with anti-CD4 (Santa Cruz, MT310, sc-19641, 1:50 dilution) and anti-CD8 (Santa Cruz, D-9, sc-7970, 1:50 dilution) primary antibodies overnight at +4 °C. After washing with phosphate buffer (PBS), secondary

(15) Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral HemorrhageAging and diseaseJune 1, 2023Zhang Z, Li Y, Shi J, Zhu L, Dai Y, Fu P, Liu S, Hong M, Zhang J, Wang J, et al.(1:250; sc-18843, Santa Cruz), rat anti-CD4 (1:250; sc-13573, Santa Cruz), mouse-anti CD8-α (1:250; sc-7970, Santa Cruz), mouse anti-CD69 (1:250; sc-373799, Santa Cruz), and rabbit anti-NKp46 (1:1000; PA5-102860,

(16) Mesenchymal Stem Cells Secretions Enhanced ATP Generation on Isolated Islets during TransplantationIsletsDecember 31, 2022Takumi Teratani, Naoya Kasahara, Yasuhiro Fujimoto, Yasunaru Sakuma, Atsushi Miki, Masafumi Goto, Naohiro Sata, Joji Kitayama150 times), anti-PDX-1 (sc-14662, Dilute 150 times), anti-Ki67 (E1870, Dilute 200 times), anti-PCNA (sc-7970, Dilute 200 times), anti-ZO1 (HP9044, Dilute 100 times), or anti-Claudin-3 (sc-17662, Dilute 100 times)

(17) Optimization of cancer immunotherapy through pyroptosis: A pyroptosis-related signature predicts survival benefit and potential synergy for immunotherapy in gliomaFrontiers in immunologyJanuary 1, 2022Zeng Y, Cai Y, Chai P, Mao Y, Chen Y, Wang L, Zeng K, Zhan Z, Xie Y, Li C, et al.for IHC to detect CD8 + T cell infiltration as previously described (26). Mouse anti-CD8-α (cat. No. sc-7970, 1:100; Santa Cruz Biotechnology, CA, USA) and goat anti-mouse secondary antibodies (Cat. No. PV-9000,

(18) TLR7/8 in the Pathogenesis of Parkinson's DiseaseInternational journal of molecular sciencesDecember 9, 2020Campolo M, Filippone A, Biondo C, Mancuso G, Casili G, Lanza M, Cuzzocrea S, Esposito E, Paterniti I.(1:500, Santa Cruz Biotechnology, sc 52480, CA, USA), and anti-CD8+ (1:500, Santa Cruz Biotechnology, sc 7970, CA, USA). Sections were washed with PBS and incubated with secondary antibody. Specific labeling was

(19) Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumorsThe Journal of clinical investigationNovember 2, 2020Wang L, Yang L, Wang C, Zhao W, Ju Z, Zhang W, Shen J, Peng Y, An C, Luu YT, et al.reagents, and plasmids. Anti-Myc (catalog sc-40), -RNF8 (catalog sc-271462) (for IP), and -CD8 (catalog sc-7970) antibodies were purchased from Santa Cruz. Anti-FLAG (catalog F1804) and –β-Actin (catalog A1978) antibodies

(20) CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancerJournal of hematology & oncologyJuly 20, 2020Wang J, Zhang R, Lin Z, Zhang S, Chen Y, Tang J, Hong J, Zhou X, Zong Y, Xu Y, et al.T lymphocytes (CD3, IF, 1:100, Abcam #ab16669), cytotoxic T cells (CD8, 1:100, IF, Santa Cruz Biotechnology #sc-7970), and Nuclei (DAPI). Based on the visual estimation of the proportion of CD3+ or CD8+ cell lymphocytes,

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4/3/2017Mouse Anti-Human CD8 (Clone D-9) Antibody Chris Corkum,Our lab frequently uses flow cytometry to investigate the role of T cell subsets in different disease states. The purpose of this experiment was to identify an antibody against CD8 for use in flow ... Read Review

CD8-α (D-9) Antibody

CD8-α (D-9) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CD8-α (D-9) Antibody from Santa Cruz Biotechnology, Inc.

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