PXR (G-11) Antibody sc-48403 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPXR (G-11) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-48403
Antibody TypePrimary Antibodies
NCBI Gene AliasesPAR, ONR1, PAR1, PXR, BXR, SXR, PAR2, PARq, PRR, SAR
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivityhuman
FormatPurified
Conjugate/TagUnconjugated
Hostmouse
NCBI Full Gene Namenuclear receptor subfamily 1 group I member 2
TargetPXR
Clonalitymonoclonal
CloneG-11
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapseOncogenesisAugust 30, 2025Lucile Bansard, Guillaume Laconde, Vanessa Delfosse, Tiphaine Huet, Margaux Ayeul, Emilie Rigal, Quentin Donati, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Luc Brunel, et al.(sc-515929, 1/500), CYP3A4 (sc-53850, 1/500), Ubiquitin (sc-166553, 1/500) and PXR (sc-48340, 1/500; or sc-48403, 1/500) from Santa Cruz, GSPT1 (ab126090, 1/500) and actin (ab253283, 1/1000) from Abcam and finally

(2) Autophagy and PXR Crosstalk in the Regulation of Cancer Drug Metabolism and Resistance According to Gene Mutational Status in Colorectal CancerGenes (Basel)July 28, 2025Evangelos Koustas, Panagiotis Sarantis, Eleni-Myrto Trifylli, Eleftheria Dikoglou-Tzanetatou, Evangelia Ioakeimidou, Ioanna A. Anastasiou, Michalis V. Karamouzis, Stamatios TheocharisPARP-1 #9542, all obtained from Cell Signaling Technology. Additionally, antibodies against PXR (G-11, sc-48403) and actin (sc-8035) were sourced from Santa Cruz Biotechnology. All antibodies were diluted at a ratio

(3) Combination of Paclitaxel and PXR Antagonist SPA70 Reverses Paclitaxel-Resistant Non-Small Cell Lung CancerCellsOctober 1, 2022Niu X, Wu T, Yin Q, Gu X, Li G, Zhou C, Ma M, Su L, Tang S, Tian Y, et al.anti-cleaved-caspase 3 (#9664, Cell Signaling Technology), P-gp (AF2245, Beyotime Biotechnology), PXR (sc-48403, Santa Cruz Biotechnology, Inc.), Tip60 (#12058, Cell Signaling Technology). Slides were imaged with

(4) High Pregnane X Receptor (PXR) Expression Is Correlated with Poor Prognosis in Invasive Breast CarcinomaDiagnostics (Basel, Switzerland)October 20, 2021Theocharis S, Giaginis C, Gourzi S, Alexandrou P, Tsourouflis G, Sarantis P, Danas E, Michail A, Tsoukalas N, Pergaris A, et al.formalin-fixed, paraffin-embedded tissue sections, using a commercially available mouse monoclonal anti-PXR (G-11, sc-48403) IgG1 primary antibody (Santa Cruz Biochemicals, Santa Cruz, CA, USA). Four μm thick tissue sections

(5) PXR-mediated expression of FABP4 promotes valproate-induced lipid accumulation in HepG2 cellsToxicology lettersAugust 1, 2021Yan L, Yang K, Wang S, Xie Y, Zhang L, Tian X.

(6) Phthalates promote the invasion of hepatocellular carcinoma cells by enhancing the interaction between Pregnane X receptor and E26 transformation specific sequence 1Pharmacological researchJuly 1, 2021Du Y, Shi X, Ma W, Wen P, Yu P, Wang X, Fang P, Chen A, Gao Z, Cui K.

(7) Immunization and Drug Metabolizing Enzymes: Focus on Hepatic Cytochrome P450 3AExpert review of vaccinesMay 1, 2021Jonsson-Schmunk K, Ghose R, Croyle MA.

(8) Rifampin Induces Expression of P-glycoprotein on the THP1 Cell-Derived Macrophages, Causing Decrease Intramacrophage Concentration of ProthionamideJournal of pharmaceutical sciencesSeptember 1, 2019Hasanuzzaman M, Yi M, Cho M, Parvez MM, Lee SJ, Shin JG.

(9) Inhibitory effect of PXR on ammonia-induced hepatocyte autophagy via P53Toxicology lettersOctober 1, 2018Yan L, Chen Z, Wu L, Su Y, Wang X, Tang N.

(10) Pregnane X receptor mediates sorafenib resistance in advanced hepatocellular carcinomaBiochimica et biophysica acta. General subjectsApril 1, 2018Feng F, Jiang Q, Cao S, Cao Y, Li R, Shen L, Zhu H, Wang T, Sun L, Liang E, et al.

(11) The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinomaPloS oneJanuary 1, 2018Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J.

(12) Pregnane X receptor is associated with unfavorable survival and induces chemotherapeutic resistance by transcriptional activating multidrug resistance-related protein 3 in colorectal cancerMolecular cancerMarch 29, 2017Dong Y, Wang Z, Xie GF, Li C, Zuo WW, Meng G, Xu CP, Li JJ.Immunohistochemistry (IHC) was performed using PXR and MRP3 antibodies (both 1:200; both from Santa Cruz Biotechnology; sc-48403 and sc-5774). Tumor cell staining was considered positive when immunoreactivity was greater than or

(13) Role of 14-3-3 sigma in over-expression of P-gp by rifampin and paclitaxel stimulation through interaction with PXRCellular signallingFebruary 1, 2017Kim SW, Md Hasanuzzaman, Cho M, Kim NH, Choi HY, Han JW, Park HJ, Oh JW, Shin JG.

(14) Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X ReceptorFrontiers in pharmacologyJanuary 1, 2017Okada N, Murakami A, Urushizaki S, Matsuda M, Kawazoe K, Ishizawa K.antibody (#4967) was purchased from Cell Signaling Technology (Beverly, MA, USA). Mouse antiPXR antibody (SC-48403) was purchased from Santa Cruz Biotechnology (Dallas, TX, USA). Horseradish peroxidaseconjugated sheep

(15) Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinomaNaunyn-Schmiedeberg's archives of pharmacologyNovember 1, 2015Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, et al.

(16) Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor ExpressionPancreasOctober 1, 2015Koutsounas I, Giaginis C, Alexandrou P, Zizi-Serbetzoglou A, Patsouris E, Kouraklis G, Theocharis S.

(17) Ginsenosides Regulate PXR/NF-κB Signaling and Attenuate Dextran Sulfate Sodium-Induced ColitisDrug metabolism and disposition: the biological fate of chemicalsAugust 1, 2015Zhang J, Cao L, Wang H, Cheng X, Wang L, Zhu L, Yan T, Xie Y, Wu Y, Zhao M, et al.

(18) Casein Kinase 2 (CK2)-mediated Phosphorylation of Hsp90β as a Novel Mechanism of Rifampin-induced MDR1 ExpressionThe Journal of biological chemistryJuly 3, 2015Kim SW, Hasanuzzaman M, Cho M, Heo YR, Ryu MJ, Ha NY, Park HJ, Park HY, Shin JG.

(19) Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXRJournal of immunology researchJanuary 1, 2015Wunsch E, Klak M, Wasik U, Milkiewicz M, Blatkiewicz M, Urasinska E, Barbier O, Bielicki D, Bogdanos DP, Elias E, et al.TBST containing 5% (w/v) milk (Merck) and then probed using the following primary antibodies: PXR (sc-48403; Santa Cruz, 1 : 500), SULT2A1 (sc-8002 Santa Cruz, 1 : 200), and anti-𝛼/𝛽-tubulin (2148, Cell Signaling,

(20) Thiazide-like diuretic drug metolazone activates human pregnane X receptor to induce cytochrome 3A4 and multidrug-resistance protein 1Biochemical pharmacologyNovember 15, 2014Banerjee M, Chen T.

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PXR (G-11) Antibody

PXR (G-11) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PXR (G-11) Antibody from Santa Cruz Biotechnology, Inc.

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